(2,6-Dimethylphenyl)arsonic Acid Induces Apoptosis through the Mitochondrial Pathway, Downregulates XIAP, and Overcomes Multidrug Resistance to Cytostatic Drugs in Leukemia and Lym...

by Nathalie Wilke, Corazon Frias, Albrecht Berkessel, Aram Prokop
Published 2024-04-01

Ruthenium Complex HB324 Induces Apoptosis via Mitochondrial Pathway with an Upregulation of Harakiri and Overcomes Cisplatin Resistance in Neuroblastoma Cells In Vitro

by Nicola L. Wilke, Hilke Burmeister, Corazon Frias, Ingo Ott, Aram Prokop
Published 2023-01-01

Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytosta...

by Jennifer Baas, Sebastian Bieringer, Corazon Frias, Jerico Frias, Carolina Soehnchen, Corinna Urmann, Steffi Ritter, Herbert Riepl, Aram Prokop
Published 2022-08-01

Novel gold(I) complexes induce apoptosis in leukemia cells via the ROS-induced mitochondrial pathway with an upregulation of Harakiri and overcome multi drug resistances in leukemi...

by Marie-C. Ahrweiler-Sawaryn, Animesh Biswas, Corazon Frias, Jerico Frias, Nicola L. Wilke, Nathalie Wilke, Albrecht Berkessel, Aram Prokop
Published 2023-05-01

The gallium complex KP46 sensitizes resistant leukemia cells and overcomes Bcl-2-induced multidrug resistance in lymphoma cells via upregulation of Harakiri and downregulation of X...

by Nicola L. Wilke, Liliane Onambele Abodo, Corazon Frias, Jerico Frias, Jennifer Baas, Michael A. Jakupec, Bernhard K. Keppler, Aram Prokop
Published 2022-12-01

B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner

by Andreas Stein, Persefoni Hilken née Thomopoulou, Corazon Frias, Sina M. Hopff, Paloma Varela, Nicola Wilke, Arul Mariappan, Jörg-Martin Neudörfl, Alexey Yu Fedorov, Jay Gopalakrishnan, Benoît Gigant, Aram Prokop, Hans-Günther Schmalz
Published 2022-01-01