A molecular/genetic approach to cerebral small-vessel disease: Beyond aging and hypertension

by Sharyl R Martini, Stephen R Williams, Paolo Moretti, Daniel Woo, Bradford B Worrall
Published 2015-01-01

Epigenome-Wide Analyses Identify Two Novel Associations With Recurrent Stroke in the Vitamin Intervention for Stroke Prevention Clinical Trial

by Nicole M. Davis Armstrong, Wei-Min Chen, Wei-Min Chen, Michael S. Brewer, Stephen R. Williams, Michèle M. Sale, Michèle M. Sale, Bradford B. Worrall, Bradford B. Worrall, Keith L. Keene, Keith L. Keene
Published 2018-09-01

Methods of a Study to Assess the Contribution of Cerebral Small Vessel Disease and Dementia Risk Alleles to Racial Disparities in Vascular Cognitive Impairment and Dementia

by Russell P. Sawyer, Bradford B. Worrall, Virginia J. Howard, Michael G. Crowe, George Howard, Hyacinth I. Hyacinth
Published 2023-09-01

Human vs. Machine Learning Based Detection of Facial Weakness Using Video Analysis

by Chad M. Aldridge, Mark M. McDonald, Mattia Wruble, Yan Zhuang, Omar Uribe, Timothy L. McMurry, Iris Lin, Haydon Pitchford, Brett J. Schneider, William A. Dalrymple, Joseph F. Carrera, Sherita Chapman, Bradford B. Worrall, Bradford B. Worrall, Gustavo K. Rohde, Gustavo K. Rohde, Andrew M. Southerland, Andrew M. Southerland
Published 2022-07-01

Diversity in genetic risk of recurrent stroke: a genome-wide association study meta-analysis

by Chad M. Aldridge, Nicole D. Armstrong, N. Abimbola Sunmonu, Christopher Becker, Deepak Palakshappa, Arne G. Lindgren, Arne G. Lindgren, Annie Pedersen, Annie Pedersen, Tara M. Stanne, Tara M. Stanne, Christina Jern, Christina Jern, Jane Maguire, Fang-Chi Hsu, Fang-Chi Hsu, Keith L. Keene, Keith L. Keene, Michele Sale, Michele Sale, Marguerite R. Irvin, Bradford B. Worrall, Bradford B. Worrall
Published 2024-02-01

DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial.

by Nicole M Davis Armstrong, Wei-Min Chen, Fang-Chi Hsu, Michael S Brewer, Natalia Cullell, Israel Fernández-Cadenas, Stephen R Williams, Michèle M Sale, Bradford B Worrall, Keith L Keene
Published 2021-01-01

Multi-omic analysis of stroke recurrence in African Americans from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial.

by Nicole M Davis Armstrong, Kelsey J Spragley, Wei-Min Chen, Fang-Chi Hsu, Michael S Brewer, Patrick J Horn, Stephen R Williams, Michèle M Sale, Bradford B Worrall, Keith L Keene
Published 2021-01-01

Genetic associations with plasma B12, B6, and folate levels in an ischemic stroke population from the Vitamin Intervention for Stroke Prevention (VISP) trial

by Keith L Keene, Keith L Keene, Wei-Min eChen, Wei-Min eChen, Fang eChen, Stephen Richardson Williams, Stacey D Elkhatib, Fang-Chi eHsu, Josyf C Mychaleckyj, Josyf C Mychaleckyj, Kimberley F Doheny, Elizabeth W Pugh, Hua eLing, Cathy C Laurie, Stephanie M Gogarten, Ebony B Madden, Bradford B Worrall, Bradford B Worrall, Michele M Sale, Michele M Sale, Michele M Sale
Published 2014-08-01

Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis.

by James F Meschia, Andrew Singleton, Michael A Nalls, Stephen S Rich, Pankaj Sharma, Luigi Ferrucci, Mar Matarin, Dena G Hernandez, Kerra Pearce, Thomas G Brott, Robert D Brown, John Hardy, Bradford B Worrall
Published 2011-01-01

Cervical Artery Dissection and Sports

by Stefan T. Engelter, Stefan T. Engelter, Christopher Traenka, Christopher Traenka, Caspar Grond-Ginsbach, Caspar Grond-Ginsbach, Tobias Brandt, Maani Hakimi, Bradford B. Worrall, Stephanie Debette, Stephanie Debette, Alessandro Pezzini, Didier Leys, Turgut Tatlisumak, Christian H. Nolte, Philippe Lyrer
Published 2021-05-01

Novel grading system for CADASIL severity: A multicenter cross-sectional study

by Bhrugun Anisetti, Elena Greco, Eldina Stojadinovic, Eric D. Goldstein, Amra Sakusic, Mohammed K. Badi, Michael D Liu, Michelle P. Lin, Chia-Chun Chiang, Fanny M Elahi, Bradford B Worrall, Derek Petrosian, Owen Ross, James F. Meschia
Published 2023-01-01

NOTCH3 variants and risk of ischemic stroke.

by Owen A Ross, Alexandra I Soto-Ortolaza, Michael G Heckman, Christophe Verbeeck, Daniel J Serie, Sruti Rayaprolu, Stephen S Rich, Michael A Nalls, Andrew Singleton, Rita Guerreiro, Emma Kinsella, Zbigniew K Wszolek, Thomas G Brott, Robert D Brown, Bradford B Worrall, James F Meschia
Published 2013-01-01

Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project[S]

by Daniel Seung Kim, David R. Crosslin, Paul L. Auer, Stephanie M. Suzuki, Judit Marsillach, Amber A. Burt, Adam S. Gordon, James F. Meschia, Mike A. Nalls, Bradford B. Worrall, W.T. Longstreth, Jr., Rebecca F. Gottesman, Clement E. Furlong, Ulrike Peters, Stephen S. Rich, Deborah A. Nickerson, Gail P. Jarvik
Published 2014-06-01

Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples

by Thomas Lillicrap, Thomas Lillicrap, Charithani B. Keragala, Dominik F. Draxler, Dominik F. Draxler, Dominik F. Draxler, Jilly Chan, Heidi Ho, Stevi Harman, Be'eri Niego, Elizabeth Holliday, Elizabeth Holliday, Christopher R. Levi, Christopher R. Levi, Christopher R. Levi, Carlos Garcia-Esperon, Carlos Garcia-Esperon, Neil Spratt, Neil Spratt, Prajwal Gyawali, Prajwal Gyawali, Andrew Bivard, Andrew Bivard, Andrew Bivard, Mark W. Parsons, Joan Montaner, Joan Montaner, Joan Montaner, Alejandro Bustamante, Israel Fernandez Cadenas, Geoffrey Cloud, Geoffrey Cloud, Jane M. Maguire, Lisa Lincz, Lisa Lincz, Lisa Lincz, Timothy Kleinig, Timothy Kleinig, John Attia, John Attia, Simon Koblar, Simon Koblar, Monica Anne Hamilton-Bruce, Monica Anne Hamilton-Bruce, Philip Choi, Philip Choi, Bradford B. Worrall, Bradford B. Worrall, Robert L. Medcalf
Published 2020-11-01

Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.

by Stephen R Williams, Qiong Yang, Fang Chen, Xuan Liu, Keith L Keene, Paul Jacques, Wei-Min Chen, Galit Weinstein, Fang-Chi Hsu, Alexa Beiser, Liewei Wang, Ebony Bookman, Kimberly F Doheny, Philip A Wolf, Michelle Zilka, Jacob Selhub, Sarah Nelson, Stephanie M Gogarten, Bradford B Worrall, Sudha Seshadri, Michèle M Sale, Genomics and Randomized Trials Network, Framingham Heart Study
Published 2014-03-01

Deep profiling of multiple ischemic lesions in a large, multi-center cohort: Frequency, spatial distribution, and associations to clinical characteristics

by Anna K. Bonkhoff, Teresa Ullberg, Teresa Ullberg, Martin Bretzner, Martin Bretzner, Sungmin Hong, Markus D. Schirmer, Robert W. Regenhardt, Kathleen L. Donahue, Marco J. Nardin, Adrian V. Dalca, Adrian V. Dalca, Anne-Katrin Giese, Mark R. Etherton, Brandon L. Hancock, Steven J. T. Mocking, Elissa C. McIntosh, John Attia, John Attia, John W. Cole, Amanda Donatti, Christoph J. Griessenauer, Christoph J. Griessenauer, Laura Heitsch, Laura Heitsch, Lukas Holmegaard, Lukas Holmegaard, Katarina Jood, Katarina Jood, Jordi Jimenez-Conde, Jordi Jimenez-Conde, Steven J. Kittner, Robin Lemmens, Robin Lemmens, Christopher R. Levi, Christopher R. Levi, Caitrin W. McDonough, James F. Meschia, Chia-Ling Phuah, Stefan Ropele, Jonathan Rosand, Jonathan Rosand, Jonathan Rosand, Jaume Roquer, Jaume Roquer, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Pankaj Sharma, Agnieszka Slowik, Alessandro Sousa, Tara M. Stanne, Daniel Strbian, Turgut Tatlisumak, Turgut Tatlisumak, Vincent Thijs, Vincent Thijs, Achala Vagal, Daniel Woo, Ramin Zand, Patrick F. McArdle, Bradford B. Worrall, Bradford B. Worrall, Christina Jern, Christina Jern, Arne G. Lindgren, Arne G. Lindgren, Jane Maguire, Ona Wu, Petrea Frid, Natalia S. Rost, Johan Wasselius, Johan Wasselius
Published 2022-08-01

White matter hyperintensity quantification in large-scale clinical acute ischemic stroke cohorts – The MRI-GENIE study

by Markus D. Schirmer, Adrian V. Dalca, Ramesh Sridharan, Anne-Katrin Giese, Kathleen L. Donahue, Marco J. Nardin, Steven J.T. Mocking, Elissa C. McIntosh, Petrea Frid, Johan Wasselius, John W. Cole, Lukas Holmegaard, Christina Jern, Jordi Jimenez-Conde, Robin Lemmens, Arne G. Lindgren, James F. Meschia, Jaume Roquer, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Pankaj Sharma, Agnieszka Slowik, Vincent Thijs, Daniel Woo, Achala Vagal, Huichun Xu, Steven J. Kittner, Patrick F. McArdle, Braxton D. Mitchell, Jonathan Rosand, Bradford B. Worrall, Ona Wu, Polina Golland, Natalia S. Rost
Published 2019-01-01

Diffusion-Weighted Imaging, MR Angiography, and Baseline Data in a Systematic Multicenter Analysis of 3,301 MRI Scans of Ischemic Stroke Patients—Neuroradiological Review Within th...

by Mattias Drake, Mattias Drake, Petrea Frid, Petrea Frid, Björn M. Hansen, Björn M. Hansen, Ona Wu, Anne-Katrin Giese, Anne-Katrin Giese, Markus D. Schirmer, Markus D. Schirmer, Kathleen Donahue, Lisa Cloonan, Robert E. Irie, Mark J. R. J. Bouts, Elissa C. McIntosh, Steven J. T. Mocking, Adrian V. Dalca, Adrian V. Dalca, Ramesh Sridharan, Huichun Xu, Eva Giralt-Steinhauer, Lukas Holmegaard, Katarina Jood, Jaume Roquer, John W. Cole, Patrick F. McArdle, Joseph P. Broderick, Jordi Jiménez-Conde, Christina Jern, Brett M. Kissela, Dawn O. Kleindorfer, Robin Lemmens, Robin Lemmens, James F. Meschia, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Pankaj Sharma, Pankaj Sharma, Agnieszka Slowik, Vincent Thijs, Vincent Thijs, Daniel Woo, Bradford B. Worrall, Steven J. Kittner, Braxton D. Mitchell, Braxton D. Mitchell, Jonathan Rosand, Jonathan Rosand, Jonathan Rosand, Polina Golland, Arne Lindgren, Arne Lindgren, Natalia S. Rost, Johan Wassélius, Johan Wassélius
Published 2020-06-01

Outcome after acute ischemic stroke is linked to sex-specific lesion patterns

by Anna K. Bonkhoff, Markus D. Schirmer, Martin Bretzner, Sungmin Hong, Robert W. Regenhardt, Mikael Brudfors, Kathleen L. Donahue, Marco J. Nardin, Adrian V. Dalca, Anne-Katrin Giese, Mark R. Etherton, Brandon L. Hancock, Steven J. T. Mocking, Elissa C. McIntosh, John Attia, Oscar R. Benavente, Stephen Bevan, John W. Cole, Amanda Donatti, Christoph J. Griessenauer, Laura Heitsch, Lukas Holmegaard, Katarina Jood, Jordi Jimenez-Conde, Steven J. Kittner, Robin Lemmens, Christopher R. Levi, Caitrin W. McDonough, James F. Meschia, Chia-Ling Phuah, Arndt Rolfs, Stefan Ropele, Jonathan Rosand, Jaume Roquer, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Pankaj Sharma, Agnieszka Slowik, Martin Söderholm, Alessandro Sousa, Tara M. Stanne, Daniel Strbian, Turgut Tatlisumak, Vincent Thijs, Achala Vagal, Johan Wasselius, Daniel Woo, Ramin Zand, Patrick F. McArdle, Bradford B. Worrall, Christina Jern, Arne G. Lindgren, Jane Maguire, Danilo Bzdok, Ona Wu, MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, Natalia S. Rost
Published 2021-06-01

Intracranial Aneurysm Classifier Using Phenotypic Factors: An International Pooled Analysis

by Sandrine Morel, Isabel C. Hostettler, Georg R. Spinner, Romain Bourcier, Joanna Pera, Torstein R. Meling, Varinder S. Alg, Henry Houlden, Mark K. Bakker, Femke van’t Hof, Gabriel J. E. Rinkel, Tatiana Foroud, Dongbing Lai, Charles J. Moomaw, Bradford B. Worrall, Jildaz Caroff, Pacôme Constant-dits-Beaufils, Matilde Karakachoff, Antoine Rimbert, Aymeric Rouchaud, Emilia I. Gaal-Paavola, Hanna Kaukovalta, Riku Kivisaari, Aki Laakso, Behnam Rezai Jahromi, Riikka Tulamo, Christoph M. Friedrich, Jerome Dauvillier, Sven Hirsch, Nathalie Isidor, Zolt Kulcsàr, Karl O. Lövblad, Olivier Martin, Paolo Machi, Vitor Mendes Pereira, Daniel Rüfenacht, Karl Schaller, Sabine Schilling, Agnieszka Slowik, Juha E. Jaaskelainen, Mikael von und zu Fraunberg, Jordi Jiménez-Conde, Elisa Cuadrado-Godia, Carolina Soriano-Tárraga, Iona Y. Millwood, Robin G. Walters, The @neurIST project, The ICAN Study Group, Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study Investigators, International Stroke Genetics Consortium (ISGC), Helen Kim, Richard Redon, Nerissa U. Ko, Guy A. Rouleau, Antti Lindgren, Mika Niemelä, Hubert Desal, Daniel Woo, Joseph P. Broderick, David J. Werring, Ynte M. Ruigrok, Philippe Bijlenga
Published 2022-08-01