The Future of Lipid-lowering Therapy

by Willemien van Zwol, Antoine Rimbert, Jan Albert Kuivenhoven
Published 2019-07-01

Generation of a GPR146 knockout human induced pluripotent stem cell line (ITXi001-A-1)

by Lise Bray, Amandine Caillaud, Aurore Girardeau, Murielle Patitucci, Cédric Le May, Bertrand Cariou, Antoine Rimbert
Published 2022-04-01

Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids

by Adriaan van der Graaf, Annique Claringbould, Antoine Rimbert, BIOS Consortium, Harm-Jan Westra, Yang Li, Cisca Wijmenga, Serena Sanna
Published 2020-10-01

Use of plasma metabolomics to analyze phenotype-genotype relationships in young hypercholesterolemic females

by Xiang Zhang, Antoine Rimbert, Willem Balder, Aeilko Having Zwinderman, Jan Albert Kuivenhoven, Geesje Margaretha Dallinga-Thie, Albert Kornelis Groen
Published 2018-11-01

Generation of an induced pluripotent stem cell line (ITXi012-A) from a patient with genetically determined high-lipoprotein(a) plasma levels

by Amandine Caillaud, Lise Bray, Aurore Girardeau, Zoé Begué-Racapé, Lucie Vince, Murielle Patitucci, Cédric Le May, Gilles Lambert, Bertrand Cariou, Antoine Rimbert
Published 2023-10-01

Germline JAK2 E846D Substitution as the Cause of Erythrocytosis?

by Nada Maaziz, Céline Garrec, Fabrice Airaud, Victor Bobée, Nathalie Contentin, Emilie Cayssials, Antoine Rimbert, Bernard Aral, Stéphane Bézieau, Betty Gardie, François Girodon
Published 2023-05-01

Low Detection Rates of Genetic FH in Cohort of Patients With Severe Hypercholesterolemia in the United Arabic Emirates

by Antoine Rimbert, Hinda Daggag, Peter Lansberg, Adam Buckley, Martijn Viel, Roan Kanninga, Lennart Johansson, Robin P. F. Dullaart, Richard Sinke, Alia Al Tikriti, Jan Albert Kuivenhoven, Maha Taysir Barakat
Published 2022-01-01

<em>APOB</em> CRISPR-Cas9 Engineering in Hypobetalipoproteinemia: A Promising Tool for Functional Studies of Novel Variants

by Xavier Vanhoye, Alexandre Janin, Amandine Caillaud, Antoine Rimbert, Fabienne Venet, Morgane Gossez, Wieneke Dijk, Oriane Marmontel, Séverine Nony, Charlotte Chatelain, Christine Durand, Pierre Lindenbaum, Jennifer Rieusset, Bertrand Cariou, Philippe Moulin, Mathilde Di Filippo
Published 2022-04-01

FACS-assisted CRISPR-Cas9 genome editing of human induced pluripotent stem cells

by Amandine Caillaud, Antoine Lévêque, Aurélie Thédrez, Aurore Girardeau, Robin Canac, Lise Bray, Manon Baudic, Julien Barc, Nathalie Gaborit, Guillaume Lamirault, Betty Gardie, Salam Idriss, Antoine Rimbert, Cédric Le May, Bertrand Cariou, Karim Si-Tayeb
Published 2022-12-01

DHCR24 inhibitor SH42 increases desmosterol without preventing atherosclerosis development in mice

by Xiaoke Ge, Bram Slütter, Joost M. Lambooij, Enchen Zhou, Zhixiong Ying, Ceren Agirman, Marieke Heijink, Antoine Rimbert, Bruno Guigas, Johan Kuiper, Christoph Müller, Franz Bracher, Martin Giera, Sander Kooijman, Patrick C.N. Rensen, Yanan Wang, Milena Schönke
Published 2024-06-01

Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans

by Sebastian Hendrix, Jenina Kingma, Roelof Ottenhoff, Masoud Valiloo, Monika Svecla, Lobke F. Zijlstra, Vinay Sachdev, Kristina Kovac, Johannes H. M. Levels, Aldo Jongejan, Jan F. de Boer, Folkert Kuipers, Antoine Rimbert, Giuseppe D. Norata, Anke Loregger, Noam Zelcer
Published 2023-08-01

The Genetic Spectrum of Familial Hypertriglyceridemia in Oman

by Khalid Al-Waili, Khalid Al-Rasadi, Muna Al-Bulushi, Mohammed Habais, Abdullah Al-Mujaini, Saif Al-Yaarubi, Antoine Rimbert, Razan Zadjali, Pegah Moradi Khaniabadi, Hamida Al-Barwani, Sana Hasary, Zayana M. Al-Dahmani, Hala Al-Badi, Almundher Al-Maawali, Fahad Zadjali
Published 2022-05-01

A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis

by Cristy R.C. Verzijl, Federico Oldoni, Natalia Loaiza, Justina C. Wolters, Antoine Rimbert, E. Tian, Weiming Yang, Dicky Struik, Marieke Smit, Niels J. Kloosterhuis, Amy J. Fernandez, Nadine L. Samara, Kelly G. Ten Hagen, Kruti Dalal, Aliona Chernish, Peggy McCluggage, Lawrence A. Tabak, Johan W. Jonker, Jan Albert Kuivenhoven
Published 2022-06-01

Comprehensive <i>in silico</i> and functional studies for classification of <i>EPAS1/HIF2A</i> genetic variants identified in patients with erythrocytosis

by Valéna Karaghiannis, Darko Maric, Céline Garrec, Nada Maaziz, Alexandre Buffet, Loïc Schmitt, Vincent Antunes, Fabrice Airaud, Bernard Aral, Amandine Le Roy, Sébastien Corbineau, Lamisse Mansour-Hendili, Valentine Lesieur, Antoine Rimbert, Fabien Laporte, Marine Delamare, Minke Rab, Stéphane Bézieau, Bruno Cassinat, Frédéric Galacteros, Anne-Paule Gimenez-Roqueplo, Nelly Burnichon, Holger Cario, Richard van Wijk, Celeste Bento, François Girodon, David Hoogewijs, Betty Gardie
Published 2023-01-01

Characterization of genetic variants in the <i>EGLN1/PHD2</i> gene identified in a European collection of patients with erythrocytosis

by Marine Delamare, Amandine Le Roy, Mathilde Pacault, Loïc Schmitt, Céline Garrec, Nada Maaziz, Matti Myllykoski, Antoine Rimbert, Valéna Karaghiannis, Bernard Aral, Mark Catherwood, Fabrice Airaud, Lamisse Mansour-Hendili, David Hoogewijs, Edoardo Peroni, Salam Idriss, Valentine Lesieur, Amandine Caillaud, Karim Si-Tayeb, Caroline Chariau, Anne Gaignerie, Minke Rab, Torsten Haferlach, Manja Meggendorfer, Stéphane Bézieau, Andrea Benetti, Nicole Casadevall, Pierre Hirsch, Christian Rose, Mathieu Wemeau, Frédéric Galacteros, Bruno Cassinat, Beatriz Bellosillo, Celeste Bento, Richard van Wijk, Petro E. Petrides, Maria Luigia Randi, Mary Frances McMullin, Peppi Koivunen, François Girodon, Betty Gardie, ECYT consortium
Published 2023-06-01

Intracranial Aneurysm Classifier Using Phenotypic Factors: An International Pooled Analysis

by Sandrine Morel, Isabel C. Hostettler, Georg R. Spinner, Romain Bourcier, Joanna Pera, Torstein R. Meling, Varinder S. Alg, Henry Houlden, Mark K. Bakker, Femke van’t Hof, Gabriel J. E. Rinkel, Tatiana Foroud, Dongbing Lai, Charles J. Moomaw, Bradford B. Worrall, Jildaz Caroff, Pacôme Constant-dits-Beaufils, Matilde Karakachoff, Antoine Rimbert, Aymeric Rouchaud, Emilia I. Gaal-Paavola, Hanna Kaukovalta, Riku Kivisaari, Aki Laakso, Behnam Rezai Jahromi, Riikka Tulamo, Christoph M. Friedrich, Jerome Dauvillier, Sven Hirsch, Nathalie Isidor, Zolt Kulcsàr, Karl O. Lövblad, Olivier Martin, Paolo Machi, Vitor Mendes Pereira, Daniel Rüfenacht, Karl Schaller, Sabine Schilling, Agnieszka Slowik, Juha E. Jaaskelainen, Mikael von und zu Fraunberg, Jordi Jiménez-Conde, Elisa Cuadrado-Godia, Carolina Soriano-Tárraga, Iona Y. Millwood, Robin G. Walters, The @neurIST project, The ICAN Study Group, Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study Investigators, International Stroke Genetics Consortium (ISGC), Helen Kim, Richard Redon, Nerissa U. Ko, Guy A. Rouleau, Antti Lindgren, Mika Niemelä, Hubert Desal, Daniel Woo, Joseph P. Broderick, David J. Werring, Ynte M. Ruigrok, Philippe Bijlenga
Published 2022-08-01