Genetic variation in <it>TIMP1 </it>but not <it>MMPs </it>predict excess FEV₁decline in two general population-based cohorts

by Blokstra A, Siedlinski M, Postma DS, van Diemen CC, Smit HA, Boezen HM
Published 2011-04-01

Vaccine-based clinical trials in ovarian cancer

by Leffers, N., Daemen, T., Boezen, H.M., Melief, K.J.M., Nijman, H.W.
Published 2011

Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease

by Budulac, S.E., Boezen, H.M., Hiemstra, P.S., Lapperre, T.S., Vonk, J.M., Timens, W., Postma, D.S., GLUCOLD Study Grp
Published 2012

Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial

by Snoeck-Stroband, J.B., Lapperre, T.S., Sterk, P.J., Hiemstra, P.S., Thiadens, H.A., Boezen, H.M., Hacken, N.H.T. ten, Kerstjens, H.A.M., Postma, D.S., Timens, W., Sont, J.K., GLUCOLD Study Grp
Published 2015

Prediction of long-term benefits of inhaled steroids by phenotypic markers in moderateto-severe COPD: A randomized controlled trial

by Snoeck-Stroband J.B., Lapperre T.S., Sterk P.J., Hiemstra P.S., Thiadens H.A., Boezen H.M., Ten Hacken N.H.T., Kerstjens H.A.M., Postma D.S., Timens W., Sont J.K.
Published 2020

Multidrug resistance-associated protein 1 and lung function decline with or without long-term corticosteroids treatment in COPD

by Budulac, S.E., Postma, D.S., Hiemstra, P.S., Lapperre, T.S., Kunz, L.I.Z., Vonk, J.M., Boezen, H.M., Timens, W., GLUCOLD Study Grp
Published 2012

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

by Romanos, J., Rosen, A., Kumar, V., Trynka, G., Franke, L., Szperl, A., Gutierrez-Achury, J., Diemen, C.C. van, Kanninga, R., Jankipersadsing, S.A., Steck, A., Eisenbarth, G., Heel, D.A. van, Cukrowska, B., Bruno, V., Mazzilli, M.C., Nunez, C., Bilbao, J.R., Mearin, M.L., Barisani, D., Rewers, M., Norris, J.M., Ivarsson, A., Boezen, H.M., Liu, E., Wijmenga, C., PreventCD Grp
Published 2014

Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD

by Dijkstra, A.E., Boezen, H.M., Berge, M. van den, Vonk, J.M., Hiemstra, P.S., Barr, R.G., Burkart, K.M., Manichaikul, A., Pottinger, T.D., Silverman, E.K., Cho, M.H., Crapo, J.D., Beaty, T.H., Bakke, P., Gulsvik, A., Lomas, D.A., Bosse, Y., Nickle, D.C., Pare, P.D., Koning, H.J. de, Lammers, J.W., Zanen, P., Smolonska, J., Wijmenga, C., Brandsma, C.A., Groen, H.J.M., Postma, D.S., Life Lines Cohort Study Grp
Published 2015

Novel Genes for Airway Wall Thickness Identified with Combined Genome-Wide Association and Expression Analyses

by Dijkstra, A.E., Postma, D.S., Ginneken, B. van, Wielputz, M.O., Schmidt, M., Becker, N., Owsijewitsch, M., Kauczor, H.U., Koning, H.J. de, Lammers, J.W., Oudkerk, M., Brandsma, C.A., Bosse, Y., Nickle, D.C., Sin, D.D., Hiemstra, P.S., Wijmenga, C., Smolonska, J., Zanen, P., Vonk, J.M., Berge, M. van den, Boezen, H.M., Groen, H.J.M.
Published 2015

Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease

by Hansel, N.N., Pare, P.D., Rafaels, N., Sin, D.D., Sandford, A., Daley, D., Vergara, C., Huang, L.L., Elliott, W.M., Pascoe, C.D., Arsenault, B.A., Postma, D.S., Boezen, H.M., Bosse, Y., Berge, M. van den, Hiemstra, P.S., Cho, M.H., Litonjua, A.A., Sparrow, D., Ober, C., Wise, R.A., Connett, J., Neptune, E.R., Beaty, T.H., Ruczinski, I., Mathias, R.A., Barnes, K.C., Lung Hlth Study
Published 2015

Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease

by Budulac S.E., Boezen H.M., Hiemstra P.S., Lapperre T.S., Vonk J.M., Timens W., Postma D.S., Kauffman H.F., de Reus D., Jansen D.F., Barentsen M.D.W., Zeinstra-Smit M., Luteijn A.J., van der Molen T., ter Veen G., Gosman M.M.E., ten Hacken N.H.T., Kerstjens H.A.M., van Maaren M.S., Veltman C.A., Verbokkem A., Verhage I., Vink-Klooster H.K., Snoeck-Stroband J.B., Thiadens H., Sont J.K., Bajema I., Gast-Strookman J., Janssen K., Rabe K.F., van Schadewijk A., Smit-Bakker J., Stolk J., Tire' A.C.J.A., van der Veen H., Wijffels M.M.E., Willems L.N.A., Sterk P.J., Mauad T.
Published 2020

Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp

by Vliet-Ostaptchouk, J.V. van, Haeften, T.W. van, Landman, G.W.D., Reiling, E., Kleefstra, N., Bilo, H.J.G., Klungel, O.H., Boer, A. de, Diemen, C.C. van, Wijmenga, C., Boezen, H.M., Dekker, J.M., Riet, E. van 't, Nijpels, G., Welschen, L.M.C., Zavrelova, H., Bruin, E.J., Elbers, C.C., Bauer, F., Onland-Moret, N.C., Schouw, Y.T. van der, Grobbee, D.E., Spijkerman, A.M.W., , D.L. van der a, Simonis-Bik, A.M., Eekhoff, E.M.W., Diamant, M., Kramer, M.H.H., Boomsma, D.I., Geus, E.J. de, Willemsen, G., Slagboom, P.E., Hofker, M.H., Hart, L.M. 't
Published 2012

Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study

by Dijkstra, A.E., Smolonska, J., Berge, M. van den, Wijmenga, C., Zanen, P., Luinge, M.A., Platteel, M., Lammers, J.W., Dahlback, M., Tosh, K., Hiemstra, P.S., Sterk, P.J., Spira, A., Vestbo, J., Nordestgaard, B.G., Benn, M., Nielsen, S.F., Dahl, M., Verschuren, W.M., Picavet, H.S.J., Smit, H.A., Owsijewitsch, M., Kauczor, H.U., Koning, H.J. de, Nizankowska-Mogilnicka, E., Mejza, F., Nastalek, P., Diemen, C.C. van, Cho, M.H., Silverman, E.K., Crapo, J.D., Beaty, T.H., Lomas, D.A., Bakke, P., Gulsvik, A., Bosse, Y., Obeidat, M.A., Loth, D.W., Lahousse, L., Rivadeneira, F., Uitterlinden, A.G., Hofman, A., Stricker, B.H., Brusselle, G.G., Duijn, C. van, Brouwer, U., Koppelman, G.H., Vonk, J.M., Nawijn, M.C., Groen, H.J.M., Timens, W., Boezen, H.M., Postma, D.S., LifeLines Cohort Study
Published 2014

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression

by Plaat, D. van der, Vonk, J.M., Terzikhan, N., Jong, K. de, Vries, M. de, Bastide-van Gemert, S. la, Diemen, C.C. van, Lahousse, L., Brusselle, G., Nedeljkovic, I., Amin, N., Kromhout, H., Vermeulen, R.C.H., Postma, D.S., Duijn, C.M. van, Boezen, H.M., Heijmans, B.T., Hoen, P.A.C.T., Meurs, J. van, Isaacs, A., Jansen, R., Franke, L., Boomsma, D.I., Pool, R., Dongen, J. van, Hottenga, J.J., Greevenbroek, M.M.J. van, Stehouwer, C.D.A., Kallen, C.J.H. van der, Schalkwijk, C.G., Wijmenga, C., Zhernakova, S., Tigchelaar, E.E., Slagboom, P.E., Beekman, M., Deelen, J., Heemst, D. van, Veldink, J.H., Berg, L.H. van den, Hofman, B.A., Uitterlinden, A.G., Jhamai, P.M., Verbiest, M., Suchiman, H.E.D., Verkerk, M., Breggen, R. van der, Rooij, J. van, Lakenberg, N., Mei, H., Iterson, M. van, Galen, M. van, Bot, J., Zhernakova, D.V., Hof, P.V., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Luijk, R., Bonder, M.J., Dijk, F. van, Arindrarto, W., Kielbasa, S.M., Swertz, M.A., Zwet, E.W. van, Hoen, P.B. 't, BIOS Consortium
Published 2019

Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD

by Budulac, S.E., Postma, D.S., Hiemstra, P.S., Kunz, L.I.Z., Siedlinski, M., Smit, H.A., Vonk, J.M., Rutgers, B., Timens, W., Boezen, H.M., Groningen Leiden Univ Corticostero
Published 2010

Real-world effects of antibiotic treatment on acute COPD exacerbations in outpatients: a cohort study under the PharmLines initiative

by Wang, Y.Y., Pera, V., Boezen, H.M., Alffenaar, J.W.C., Wilffert, B., Groenwold, R.H.H., Hak, E.
Published 2022

Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk

by Festen, E.A.M., Stokkers, P.C.F., Diemen, C.C. van, Bodegraven, A.A. van, Boezen, H.M., Crusius, B.J.A., Hommes, D.W., Woude, J.C. van der, Balschun, T., Verspaget, H.W., Schreiber, S., Jong, D.J. de, Franke, A., Dijkstra, G., Wijmenga, C., Weersma, R.K.
Published 2010

Association of PAI-1 Gene Polymorphism With Survival and Chemotherapy-Related Vascular Toxicity in Testicular Cancer

by Haas, E.C. de, Zwart, N., Meijer, C., Suurmeijer, A.J.H., Meijer, K., Guchelaar, H.J., Hoekstra, H.J., Leeuwen, F.E. van, Sleijfer, D.T., Boezen, H.M., Gietema, J.A.
Published 2010

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

by Wyss, A.B., Sofer, T., Lee, M.K., Terzikhan, N., Nguyen, J.N., Lahousse, L., Latourelle, J.C., Smith, A.V., Bartz, T.M., Feitosa, M.F., Gao, W., Ahluwalia, T.S., Tang, W.B., Oldmeadow, C., Duan, Q., Jong, K. de, Wojczynski, M.K., Wang, X.Q., Noordam, R., Hartwig, F.P., Jackson, V.E., Wang, T.Y., Obeidat, M., Hobbs, B.D., Huan, T.X., Gui, H.S., Parker, M.M., Hu, D.L., Mogil, L.S., Kichaev, G., Jin, J.P., Graff, M., Harris, T.B., Kalhan, R., Heckbert, S.R., Paternoster, L., Burkart, K.M., Liu, Y.M., Holliday, E.G., Wilson, J.G., Vonk, J.M., Sanders, J.L., Barr, R.G., Mutsert, R. de, Menezes, A.M.B., Adams, H.H.H., Berge, M. van den, Joehanes, R., Levin, A.M., Liberto, J., Launer, L.J., Morrison, A.C., Sitlani, C.M., Celedon, J.C., Kritchevsky, S.B., Scott, R.J., Christensen, K., Rotter, J.I., Bonten, T.N., Wehrmeister, F.C., Bosse, Y., Xiao, S.J., Oh, S., Franceschini, N., Brody, J.A., Kaplan, R.C., Lohman, K., McEvoy, M., Province, M.A., Rosendaal, F.R., Taylor, K.D., Nickle, D.C., Williams, L.K., Burchard, E.G., Wheeler, H.E., Sin, D.D., Gudnason, V., North, K.E., Fornage, M., Psaty, B.M., Myers, R.H., O'Connor, G., Hansen, T., Laurie, C.C., Cassano, P.A., Sung, J., Kim, W.J., Attia, J.R., Lange, L., Boezen, H.M., Thyagarajan, B., Rich, S.S., Mook-Kanamori, D.O., Horta, B.L., Uitterlinden, A.G., , H.K. im, Cho, M.H., Brusselle, G.G., Gharib, S.A., Dupuis, J., Manichaikul, A., London, S.J.
Published 2018

Antigen-specific active immunotherapy for ovarian cancer

by Leffers, N., Daemen, T., Helfrich, W., Boezen, H.M., Cohlen, B.J., Melief, K., Nijman, H.W.
Published 2010