A common gene variant in glucokinase regulatory protein interacts with glucose metabolism on diabetic dyslipidaemia: the combined CODAM and Hoorn studies

by Simons, N., Dekker, J.M., Greevenbroek, M.M.J. van, Nijpels, G., Hart, L.M. 't, Kallen, C.J.H. van der, Schalkwijk, C.G., Schaper, N.C., Stehouwer, C.D.A., Brouwers, M.C.G.
Published 2016

A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies

by Simons, N., Dekker, J.M., Greevenbroek, M.M.J. van, Nijpels, G., Hart, L.M. 't, Kallen, C.J.H. van der, Schalkwijk, C.G., Schaper, N.C., Stehouwer, C.D.A., Brouwers, M.C.G.J.
Published 2016

BclI glucocorticoid receptor polymorphism in relation to cardiovascular variables: the Hoorn and CODAM studies

by Moorsel, D. van, Greevenbroek, M.M.J. van, Schaper, N.C., Henry, R.M.A., Geelen, C.C., Rossum, E.F.C. van, Nijpels, G., Hart, L.M. 't, Schalkwijk, C.G., Kallen, C.J.H. van der, Sauerwein, H.P., Dekker, J.M., Stehouwer, C.D.A., Havekes, B.
Published 2015

Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes

by Hart, L.M. 't, Vogelzangs, N., Mook-Kanamori, D.O., Brahimaj, A., Nano, J., Heijden, A.A.W.A. van der, Dijk, K.W. van, Slieker, R.C., Steyerberg, E.W., Ikram, M.A., Beekman, M., Boomsma, D.I., Duijn, C.M. van, Slagboom, P.E., Stehouwer, C.D.A., Schalkwijk, C.G., Arts, I.C.W., Dekker, J.M., Dehghan, A., Muka, T., Kallen, C.J.H. van der, Nijpels, G., Greevenbroek, M.M.J. van
Published 2018

Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms

by Slieker, R.C., Iterson, M. van, Luijk, R., Beekman, M., Zhernakova, D.V., Moed, M.H., Mei, H.L., Galen, M. van, Deelen, P., Bonder, M.J., Zhernakova, A., Uitterlinden, A.G., Tigchelaar, E.F., Stehouwer, C.D.A., Schalkwijk, C.G., Kallen, C.J.H. van der, Hofman, A., Heemst, D. van, Geus, E.J. de, Dongen, J. van, Deelen, J., Berg, L.H. van den, Meurs, J. van, Jansen, R., Hoen, P.A.C. 't, Franke, L., Wijmenga, C., Veldink, J.H., Swertz, M.A., Greevenbroek, M.M.J. van, Duijn, C.M. van, Boomsma, D.I., Slagboom, P.E., Heijmans, B.T., BIOS Consortium
Published 2016

Blood lipids influence DNA methylation in circulating cells

by Dekkers, K.F., Iterson, M. van, Slieker, R.C., Moed, M.H., Bonder, M.J., Galen, M. van, Mei, H.L., Zhernakova, D.V., Berg, L.H. van den, Deelen, J., Dongen, J. van, Heemst, D. van, Hofman, A., Hottenga, J.J., Kallen, C.J.H. van der, Schalkwijk, C.G., Stehouwer, C.D.A., Tigchelaar, E.F., Uitterlinden, A.G., Willemsen, G., Zhernakova, A., Franke, L., Hoen, P.A.C. 't, Jansen, R., Meurs, J. van, Boomsma, D.I., Duijn, C.M. van, Greevenbroek, M.M.J. van, Veldink, J.H., Wijmenga, C., Zwet, E.W. van, Slagboom, P.E., Jukema, J.W., Heijmans, B.T., BIOS Consortium
Published 2016

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

by Onderwater, G.L.J., Ligthart, L., Bot, M., Demirkan, A., Fu, J.Y., Kallen, C.J.H. van der, Vijfhuizen, L.S., Pool, R., Liu, J., Vanmolkot, F.H.M., Beekman, M., Wen, K.X., Amin, N., Thesing, C.S., Pijpers, J.A., Kies, D.A., Zielman, R., Boer, I. de, Greevenbroek, M.M.J. van, Arts, I.C.W., Milaneschi, Y., Schram, M.T., Dagnelie, P.C., Franke, L., Ikram, M.A., Ferrari, M.D., Goeman, J.J., Slagboom, P.E., Wijmenga, C., Stehouwer, C.D.A., Boomsma, D.I., Duijn, C.M. van, Penninx, B.W., Hoen, P.A.C. 't, Terwindt, G.M., Maagdenberg, A.M.J.M. van den, BBMRI Metabolomics Consortium
Published 2019

Identification of context-dependent expression quantitative trait loci in whole blood

by Zhernakova, D.V., Deelen, P., Vermaat, M., Iterson, M. van, Galen, M. van, Arindrarto, W., Hof, P. van 't, Mei, H.L., Dijk, F. van, Westra, H.J., Bonder, M.J., Rooij, J. van, Verkerk, M., Jhamai, P.M., Moed, M., Kielbasa, S.M., Bot, J., Nooren, I., Pool, R., Dongen, J. van, Hottenga, J.J., Stehouwer, C.D.A., Kallen, C.J.H. van der, Schalkwijk, C.G., Zhernakova, A., Li, Y., Tigchelaar, E.F., Klein, N. de, Beekman, M., Deelen, J., Heemst, D. van, Berg, L.H. van den, Hofman, A., Uitterlinden, A.G., Greevenbroek, M.M.J. van, Veldink, J.H., Boomsma, D.I., Duijn, C.M. van, Wijmenga, C., Slagboom, P.E., Swertz, M.A., Isaacs, A., Meurs, J.B.J. van, Jansen, R., Heijmans, B.T., Hoen, P.A.C. 't, Franke, L.
Published 2017

Disease variants alter transcription factor levels and methylation of their binding sites

by Bonder, M.J., Luijk, R., Zhernakova, D.V., Moed, M., Deelen, P., Vermaat, M., Iterson, M. van, Dijk, F. van, Galen, M. van, Bot, J., Slieker, R.C., Jhamai, P.M., Verbiest, M., Suchiman, H.E.D., Verkerk, M., Breggen, R. van der, Rooij, J. van, Lakenberg, N., Arindrarto, W., Kielbasa, S.M., Jonkers, I., Hof, P. van 't, Nooren, I., Beekman, M., Deelen, J., Heemst, D. van, Zhernakova, A., Tigchelaar, E.F., Swertz, M.A., Hofman, A., Uitterlinden, A.G., Pool, R., Dongen, J. van, Hottenga, J.J., Stehouwer, C.D.A., Kallen, C.J.H. van der, Schalkwijk, C.G., Berg, L.H. van den, Zwet, E.W. van, Mei, H.L., Li, Y., Lemire, M., Hudson, T.J., Slagboom, P.E., Wijmenga, C., Veldink, J.H., Greevenbroek, M.M.J. van, Duijn, C.M. van, Boomsma, D.I., Isaacs, A., Jansen, R., Meurs, J.B.J. van, Hoen, P.A.C. 't, Franke, L., Heijmans, B.T., BIOS Consortium
Published 2017

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

by Mandaviya, P.R., Joehanes, R., Brody, J., Castillo-Fernandez, J.E., Dekkers, K.F., , A.N. do, Graff, M., Hanninen, I.K., Tanaka, T., Jonge, E.A.L. de, Kiefte-de Jong, J.C., Absher, D.M., Aslibekyan, S., Rijke, Y.B. de, Fornage, M., Hernandez, D.G., Hurme, M.A., Ikram, M.A., Jacques, P.F., Justice, A.E., Kiel, D.P., Lemaitre, R.N., Mendelson, M.M., Mikkila, V., Moore, A.Z., Pallister, T., Raitakari, O.T., Schalkwijk, C.G., Sha, J., Slagboom, E.P.E., Smith, C.E., Stehouwer, C.D.A., Tsai, P.C., Uitterlinden, A.G., Kallen, C.J.H. van der, Heemst, D. van, Arnett, D.K., Bandinelli, S., Bell, J.T., Heijmans, B.T., Lehtimaki, T., Levy, D., North, K.E., Sotoodehnia, N., Greevenbroek, M.M.J. van, Meurs, J.B.J. van, Heil, S.G., BIOS Consortium, CHARGE Consortium Epigenetics, CHARGE Consortium Nutr Working Grp
Published 2019

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

by Dongen, J. van, Zilhao, N.R., Sugden, K., Hannon, E.J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D.L., Moffitt, T.E., Poulton, R., Franke, B., Boomsma, D.I., Heijmans, B.T., t'Hoen, P.A.G., Meurs, J. van, Isaacs, A., Jansen, R., Franke, L., Pool, R., Hottenga, J.J., Greevenbroek, M.M.J. van, Stehouwer, C.D.A., Kallen, C.J.H. van der, Schalkwijk, C.G., Wijmenga, C., Zhernakova, S., Tigchelaar, E.F., Slagboom, P.E., Beekman, M., Deelen, J., Heemst, D. van, Veldink, J.H., Berg, L.H. van den, Duijn, C.M. van, Hofman, B.A., Uitterlinden, A.G., Jhamai, P.M., Verbiest, M., Suchiman, H.E.D., Verkerk, M., Breggen, R. van der, Rooij, J. van, Lakenberg, N., Mei, H.L., Iterson, M. van, Galen, M. van, Bot, J., Zhernakova, D.V., t'Hof, P. van, Deelen, P., Nooren, I., Moed, M., Vermaat, M., Luijk, R., Bonder, M.J., Dijk, F. van, Arindrarto, W., Kielbasa, S.M., Swertz, M.A., Zwet, E.W. van, t'Hoen, P.B., BIOS Consortium
Published 2019

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression

by Plaat, D. van der, Vonk, J.M., Terzikhan, N., Jong, K. de, Vries, M. de, Bastide-van Gemert, S. la, Diemen, C.C. van, Lahousse, L., Brusselle, G., Nedeljkovic, I., Amin, N., Kromhout, H., Vermeulen, R.C.H., Postma, D.S., Duijn, C.M. van, Boezen, H.M., Heijmans, B.T., Hoen, P.A.C.T., Meurs, J. van, Isaacs, A., Jansen, R., Franke, L., Boomsma, D.I., Pool, R., Dongen, J. van, Hottenga, J.J., Greevenbroek, M.M.J. van, Stehouwer, C.D.A., Kallen, C.J.H. van der, Schalkwijk, C.G., Wijmenga, C., Zhernakova, S., Tigchelaar, E.E., Slagboom, P.E., Beekman, M., Deelen, J., Heemst, D. van, Veldink, J.H., Berg, L.H. van den, Hofman, B.A., Uitterlinden, A.G., Jhamai, P.M., Verbiest, M., Suchiman, H.E.D., Verkerk, M., Breggen, R. van der, Rooij, J. van, Lakenberg, N., Mei, H., Iterson, M. van, Galen, M. van, Bot, J., Zhernakova, D.V., Hof, P.V., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Luijk, R., Bonder, M.J., Dijk, F. van, Arindrarto, W., Kielbasa, S.M., Swertz, M.A., Zwet, E.W. van, Hoen, P.B. 't, BIOS Consortium
Published 2019

Sex differences in the risk of vascular disease associated with diabetes

by Ritter , R. de, Jong , M. de, Vos, R.C., Kallen, C.J.H. van der, Sep, S.J.S., Woodward, M., Stehouwer, C.D.A., Bots, M.L., Peters, S.A.E.
Published 2020

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

by Liu, J., Lahousse, L., Nivard, M.G., Bot, M., Chen, L.M., Klinken, J.B. van, Thesing, C.S., Beekman, M., Akker, E.B. van den, Slieker, R.C., Waterham, E., Kallen, C.J.H. van der, Boer, I. de, Li-Gao, R.F., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L.J.M., Murad, S.D., Uitterlinden, A.G., Willemsen, G., Pool, R., Milaneschi, Y., Heemst, D. van, Suchiman, H.E.D., Rutters, F., Elders, P.J.M., Beulens, J.W.J., Heijden, A.A.W.A. van der, Greevenbroek, M.M.J. van, Arts, I.C.W., Onderwater, G.L.J., Maagdenberg, A.M.J.M. van den, Mook-Kanamori, D.O., Hankemeier, T., Terwindt, G.M., Stehouwer, C.D.A., Geleijnse, J.M., Hart, L.M. 't, Slagboom, P.E., Dijk, K.W. van, Zhernakova, A., Fu, J.Y., Penninx, B.W.J.H., Boomsma, D.I., Demirkan, A., Stricker, B.H.C., Duijn, C.M. van
Published 2020

The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease

by Simons, N., Bijnen, M., Wouters, K.A.M., Rensen, S.S., Beulens, J.W.J., Greevenbroek, M.M.J. van, Hart, L.M. 't, Greve, J.W.M., Kallen, C.J.H. van der, Schaper, N.C., Schalkwijk, C.G., Stehouwer, C.D.A., Brouwers, M.C.G.J.
Published 2020

Metabolic age based on the BBMRI-NL H-1-NMR metabolomics repository as biomarker of age-related disease

by Akker, E.B. van den, Trompet, S., Wolf, J.J.H.B., Beekman, M., Suchiman, H.E.D., Deelen, J., Asselbergs, F.W., Boersma, E., Cats, D., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Kloppenburg, M., Mei, H., Meulenbelt, I., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Slofstra, M., Stehouwer, C.D.A., Swertz, M.A., Teunissen, C.E., Terwindt, G.M., Hart, L.M. 't, Maagdenberg, A.M.J.M. van den, Harst, P. van der, Horst, I.C.C. van der, Kallen, C.J.H. van der, Greevenbroek, M.M.J. van, Spil, W.E. van, Wijmenga, C., Zhernakova, A., Zwinderman, A.H., Sattar, N., Jukema, J.W., Duijn, C.M. van, Boomsma, D.I., Reinders, M.J.T., Slagboom, P.E.
Published 2020

Correction to: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies (vol 11, 39, 2020)

by Hagenbeek, F.A., Pool, R., Dongen, J. van, Draisma, H.M., Hottenga, J.J., Willemsen, G., Abdellaoui, A., Fedko, I.O., Braber, A. den, Visser, P.J., Geus, E.J.C.N. de, Duijn, C.M. van, Harms, A.C., Bartels, M., Nivard, M.G., Boomsma, D.I., Hankemeier, T., Beulens, J.W., Rutters, F., Flier, W.M. van der, Hart, L.M., Bom, J.A. van der, Kloppenburg, M., Harst, P. van der, Bomer, N., Hilten, J.A. van, So-Osman, C., Meessen, J.M.T.A., Fu, J., Wijmenga, C., Zhernikova, A., Slofstra, M., Swertz, M., Onderwater, G.L.J., Terwindt, G.M., Heijden, A.A.W.A. van der, Asselbergs, F.W., Boersma, E., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Stehouwer, C.D.A., Kallen, C.J.H. van der, Greevenbroek, M.M.J. van, Teunissen, C.E., Maagdenberg, A.M.J.M. van den, Horst I.C.C. van der, Spil, W.E. van, Zwinderman, A.H., Jukema, J.W., Mei, H., Akker, E.B. van den, Reinders M.J.T., Deelen, J., Abdel Abdellaoui
Published 2020

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

by Liu, J., Lahousse, L., Nivard, M.G., Bot, M., Chen, L.M., Klinken, J.B. van, Thesing, C.S., Beekman, M., Akker, E.B. van den, Slieker, R.C., Waterham, E., Kallen, C.J.H. van der, Boer, I. de, Li-Gao, R.F., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L.J.M., Murad, S.D., Uitterlinden, A.G., Willemsen, G., Pool, R., Milaneschi, Y., Heemst, D. van, Suchiman, H.E.D., Rutters, F., Elders, P.J.M., Beulens, J.W.J., Heijden, A.A.W.A. van der, Greevenbroek, M.M.J. van, Arts, I.C.W., Onderwater, G.L.J., Maagdenberg, A.M.J.M. van den, Mook-Kanamori, D.O., Hankemeier, T., Terwindt, G.M., Stehouwer, C.D.A., Geleijnse, J.M., 't Hart, L.M., Slagboom, P.E., Dijk, K.W. van, Zhernakova, A., Fu, J.Y., Penninx, B.W.J.H., Boomsma, D.I., Demirkan, A., Stricker, B.H.C., Duijn, C.M. van
Published 2020

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

by Porcu, E., Rueger, S., Lepik, K., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Bonder, M.J., Boomsma, D., Christiansen, M., Claringbould, A., Deelen, P., Esko, T., Fave, M.J., Franke, L., Frayling, T., Gharib, S.A., Gibson, G., Heijmans, B.T., Hemani, G., Jansen, R., Kahonen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Kovacs, P., Krohn, K., Kronberg-Guzman, J., Kukushkina, V., Lee, B., Lehtimaki, T., Loeffler, M., Marigorta, U.M., Mei, H.L., Milani, L., Montgomery, G.W., Muller-Nurasyid, M., Nauck, M., Nivard, M., Penninx, B., Perola, M., Pervjakova, N., Pierce, B.L., Powell, J., Prokisch, H., Psaty, B.M., Raitakari, O.T., Ripatti, S., Rotzschke, O., Saha, A., Scholz, M., Schramm, K., Seppala, I., Slagboom, E.P., Stehouwer, C.D.A., Stumvoll, M., Sullivan, P., Hoen, P.A.C. 't, Teumer, A., Thiery, J., Tong, L., Tonjes, A., Dongen, J. van, Iterson, M. van, Meurs, J. van, Veldink, J.H., Verlouw, J., Visscher, P.M., Volker, U., Vosa, U., Westra, H.J., Wijmenga, C., Yaghootkar, H., Yang, J., Zeng, B., Zhang, F.T., Beekman, M., Boomsma, D.I., Bot, J., Deelen, J., Hofman, B.A., Hottenga, J.J., Isaacs, A., Jhamai, P.M., Kielbasa, S.M., Lakenberg, N., Luijk, R., Mei, H., Moed, M., Nooren, I., Pool, R., Schalkwijk, C.G., Slagboom, P.E., Suchiman, H.E.D., Swertz, M.A., Tigchelaar, E.F., Uitterlinden, A.G., Berg, L.H. van den, Breggen, R. van der, Kallen, C.J.H. van der, Dijk, F. van, Duijn, C.M. van, Galen, M. van, Greevenbroek, M.M.J. van, Heemst, D. van, Rooij, J. van, Van't Hof, P., Zwet, E.W. van, Vermaat, M., Verbiest, M., Verkerk, M., Zhernakova, D.V., Zhernakova, S., Santoni, F.A., Reymond, A., Kutalik, Z., eQTLGen Consortium, BIOS Consortium
Published 2019

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

by Onderwater, G.L.J., Ligthart, L., Bot, M., Demirkan, A., Fu, J.Y., Kallen, C.J.H. van der, Vijfhuizen, L.S., Pool, R., Liu, J., Vanmolkot, F.H.M., Beekman, M., Wen, K.X., Amin, N., Thesing, C.S., Pijpers, J.A., Kies, D.A., Zielman, R., Boer, I. de, Greevenbroek, M.M.J. van, Arts, I.C.W., Milaneschi, Y., Schram, M.T., Dagnelie, P.C., Franke, L., Ikram, M.A., Ferrari, M.D., Goeman, J.J., Slagboom, P.E., Wijmenga, C., Stehouwer, C.D.A., Boomsma, D.I., Duijn, C.M. van, Penninx, B.W., Hoen, P.A.C. 't, Terwindt, G.M., Maagdenberg, A.M.J.M. van den, BBMRI Metabolomics Consortium
Published 2019