Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma

by Simone Hettmer, Anna C Schinzel, Daria Tchessalova, Michaela Schneider, Christina L Parker, Roderick T Bronson, Nigel GJ Richards, William C Hahn, Amy J Wagers
Published 2015-10-01

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

by So Young Kim, Ian F Dunn, Ron Firestein, Piyush Gupta, Leslie Wardwell, Kara Repich, Anna C Schinzel, Ben Wittner, Serena J Silver, David E Root, Jesse S Boehm, Sridhar Ramaswamy, Eric S Lander, William C Hahn
Published 2010-02-01

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

by Tovah A. Day, Jacob V. Layer, J. Patrick Cleary, Srijoy Guha, Kristen E. Stevenson, Trevor Tivey, Sunhee Kim, Anna C. Schinzel, Francesca Izzo, John Doench, David E. Root, William C. Hahn, Brendan D. Price, David M. Weinstock
Published 2017-04-01

Correction: Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

by Tovah A. Day, Jacob V. Layer, J. Patrick Cleary, Srijoy Guha, Kristen E. Stevenson, Trevor Tivey, Sunhee Kim, Anna C Schinzel, Francesca Izzo, John Doench, David E. Root, William C. Hahn, Brendan D. Price, David M. Weinstock
Published 2017-06-01

Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma

by Hettmer, Simone, Schinzel, Anna C, Tchessalova, Daria, Schneider, Michaela, Parker, Christina L, Bronson, Roderick T, Richards, Nigel GJ, Hahn, William C, Wagers, Amy J
Published 2016

Initial genome sequencing and analysis of multiple myeloma

by Chapman, Michael A., Lawrence, Michael S., Keats, Jonathan J., Cibulskis, Kristian, Sougnez, Carrie, Schinzel, Anna C., Harview, Christina L., Brunet, Jean-Philippe, Ahmann, Gregory J., Adli, Mazhar, Anderson, Kenneth C., Ardlie, Kristin, Auclair, Daniel, Baker, Angela, Bergsagel, P. Leif, Bernstein, Bradley E., Drier, Yotam, Fonseca, Rafael, Gabriel, Stacey B., Lander, Eric Steven
Published 2014

CK1\(\varepsilon\) is Required for Breast Cancers Dependent on \(\beta\)-Catenin Activity

by Firestein, Ron, Gupta, Piyush, Repich, Kara, Silver, Serena J., Boehm, Jesse S., Kim, So Young, Dunn, Ian Frederick, Wardwell, Leslie, Schinzel, Anna, Wittner, Ben, Root, David E., Ramaswamy, Sridhar, Lander, Eric Steven, Hahn, William C.
Published 2013

An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma

by Baratta, Maria Giuseppina, Schinzel, Anna, Zwang, Yaara, Bandopadhayay, Pratiti, Bowman-Colin, Christian, Kutt, Jennifer, Curtis, Jennifer, Piao, Huiying, Wong, Laura, Kung, Andrew, Beroukhim, Rameen, Bradner, James, Drapkin, Ronny, Hahn, William, Liu, Joyce, Livingston, David
Published 2019

Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells

by Scholl, Claudia, Frohling, Stefan, Dunn, Ian F., Schinzel, Anna C., Barbie, David A., Kim, So Young, Silver, Serena J., Tamayo, Pablo, Wadlow, Raymond C., Ramaswamy, Sridhar, Dohner, Konstanze, Bullinger, Lars, Sandy, Peter, Boehm, Jesse S., Root, David E., Hahn, William C., Gilliland, D. Gary, Jacks, Tyler E
Published 2015

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

by Sandy, Peter, Meylan, Etienne, Reiling, Jan H., Hoersch, Sebastian, Barbie, David A., Tamayo, Pablo, Boehm, Jesse S., Kim, So Young, Moody, Susan E., Dunn, Ian F., Schinzel, Anna C., Scholl, Claudia, Frohling, Stefan, Chan, Edmond M., Sos, Martin L., Michel, Kathrin, Mermel, Craig H., Sabatini, David, Lander, Eric Steven, Jacks, Tyler E
Published 2014