TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing

by Jakub Luptak, Donna L. Mallery, Aminu S. Jahun, Anna Albecka, Dean Clift, Osaid Ather, Greg Slodkowicz, Ian Goodfellow, Leo C. James
Published 2022-07-01

Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.

by Guido Papa, Donna L Mallery, Anna Albecka, Lawrence G Welch, Jérôme Cattin-Ortolá, Jakub Luptak, David Paul, Harvey T McMahon, Ian G Goodfellow, Andrew Carter, Sean Munro, Leo C James
Published 2021-01-01

TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control

by Christopher H. Douse, Iva A. Tchasovnikarova, Richard T. Timms, Anna V. Protasio, Marta Seczynska, Daniil M. Prigozhin, Anna Albecka, Jane Wagstaff, James C. Williamson, Stefan M. V. Freund, Paul J. Lehner, Yorgo Modis
Published 2020-10-01

Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases

by Javier Castillo-Olivares, David A. Wells, David A. Wells, Matteo Ferrari, Matteo Ferrari, Andrew C. Y. Chan, Peter Smith, Angalee Nadesalingam, Minna Paloniemi, George W. Carnell, Luis Ohlendorf, Diego Cantoni, Martin Mayora-Neto, Phil Palmer, Paul Tonks, Nigel J. Temperton, David Peterhoff, Patrick Neckermann, Ralf Wagner, Ralf Wagner, Rainer Doffinger, Sarah Kempster, Ashley D. Otter, Amanda Semper, Tim Brooks, Anna Albecka, Leo C. James, Mark Page, Wilhelm Schwaeble, Helen Baxendale, Jonathan L. Heeney
Published 2021-11-01

Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2

by Katherine U. Gaynor, Marina Vaysburd, Maximilian A. J. Harman, Anna Albecka, Phillip Jeffrey, Paul Beswick, Guido Papa, Liuhong Chen, Donna Mallery, Brian McGuinness, Katerine Van Rietschoten, Steven Stanway, Paul Brear, Aleksei Lulla, Katarzyna Ciazynska, Veronica T. Chang, Jo Sharp, Megan Neary, Helen Box, Jo Herriott, Edyta Kijak, Lee Tatham, Eleanor G. Bentley, Parul Sharma, Adam Kirby, Ximeng Han, James P. Stewart, Andrew Owen, John A. G. Briggs, Marko Hyvönen, Michael J. Skynner, Leo C. James
Published 2023-06-01