HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened[S]

by Mustafa Yalcinkaya, Anja Kerksiek, Katrin Gebert, Wijtske Annema, Rahel Sibler, Silvija Radosavljevic, Dieter Lütjohann, Lucia Rohrer, Arnold von Eckardstein
Published 2020-04-01

Plant sterols and cholesterol metabolism are associated with five-year cognitive decline in the elderly population

by Christopher Clark, Mehdi Gholam, Leonardo Zullo, Anja Kerksiek, Enrique Castelao, Armin von Gunten, Martin Preisig, Dieter Lütjohann, Julius Popp
Published 2023-06-01

Cholesterol-metabolism, plant sterols, and long-term cognitive decline in older people – Effects of sex and APOEe4

by Matteo Spinedi, Christopher Clark, Leonardo Zullo, Anja Kerksiek, Giorgio Pistis, Enrique Castelao, Armin von Gunten, Martin Preisig, Dieter Lütjohann, Julius Popp
Published 2024-02-01

Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function

by Marietta Fabiano, Naoto Oikawa, Anja Kerksiek, Jun-ichi Furukawa, Hirokazu Yagi, Koichi Kato, Ulrich Schweizer, Wim Annaert, Jongkyun Kang, Jie Shen, Dieter Lütjohann, Jochen Walter
Published 2024-05-01

Dietary intake of plant sterols stably increases plant sterol levels in the murine brain

by Tim Vanmierlo, Oliver Weingärtner, Susanne van der Pol, Constanze Husche, Anja Kerksiek, Silvia Friedrichs, Eric Sijbrands, Harry Steinbusch, Marcus Grimm, Tobias Hartmann, Ulrich Laufs, Michael Böhm, Helga E. de Vries, Monique Mulder, Dieter Lütjohann
Published 2012-04-01

24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease

by Nikita Martens, Melissa Schepers, Na Zhan, Frank Leijten, Gardi Voortman, Assia Tiane, Ben Rombaut, Janne Poisquet, Nienke van de Sande, Anja Kerksiek, Folkert Kuipers, Johan W. Jonker, Hongbing Liu, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder
Published 2021-03-01

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

by Júlia Canet-Pons, Nesli-Ece Sen, Aleksandar Arsović, Luis-Enrique Almaguer-Mederos, Melanie V. Halbach, Jana Key, Claudia Döring, Anja Kerksiek, Gina Picchiarelli, Raphaelle Cassel, Frédérique René, Stéphane Dieterlé, Nina V. Fuchs, Renate König, Luc Dupuis, Dieter Lütjohann, Suzana Gispert, Georg Auburger
Published 2021-05-01