The GPIIb-IIIa defect of platelets in Glanzmann thrombasthenia

by Alan T. Nurden
Published 2023-04-01

Personal reflections on the early contributions of Gus Born to platelet research

by Alan T Nurden
Published 2018-11-01

High-throughput sequencing for rapid diagnosis of inherited platelet disorders: a case for a European consensus

by Alan T. Nurden, Paquita Nurden
Published 2018-01-01

Inherited thrombocytopenias: history, advances and perspectives

by Alan T. Nurden, Paquita Nurden
Published 2020-08-01

Is the mysterious platelet receptor GPV an unsuspected major target for platelet autoantibodies?

by Paquita Nurden, Alan T Nurden
Published 2019-06-01

Inherited thrombocytopenias

by Alan T. Nurden, Paquita Nurden
Published 2007-09-01

ITGA2B and ITGB3 gene mutations associated with Glanzmann thrombasthenia

by Alan T. Nurden, Xavier Pillois
Published 2018-01-01

Inherited platelet diseases with normal platelet count: phenotypes, genotypes and diagnostic strategy

by Paquita Nurden, Simon Stritt, Remi Favier, Alan T. Nurden
Published 2020-11-01

Platelet morphological changes in 2 patients with von Willebrand disease type 3 caused by large homozygous deletions of the von Willebrand factor gene

by Paquita Nurden, Alan T Nurden, Silvia La Marca, Margherita Punzo, Luciano Baronciani, Augusto B. Federici
Published 2009-11-01

Molecular dynamics analysis of a novel β3 Pro189Ser mutation in a patient with glanzmann thrombasthenia differentially affecting αIIbβ3 and αvβ3 expression.

by Michel Laguerre, Essa Sabi, Martina Daly, Jacqueline Stockley, Paquita Nurden, Xavier Pillois, Alan T Nurden
Published 2013-01-01

A novel variant Glanzmann thrombasthenia due to co-inheritance of a loss- and a gain-of-function mutation of ITGB3: evidence of a dominant effect of gain-of-function mutations

by Loredana Bury, Eva Zetterberg, Eva B. Leinøe, Emanuela Falcinelli, Alessandro Marturano, Giorgia Manni, Alan T. Nurden, Paolo Gresele
Published 2018-06-01

Marked bleeding diathesis in patients with platelet dysfunction due to a novel mutation in RASGRP2, encoding CalDAG-GEFI (p.Gly305Asp)

by Emilse Bermejo, Maria F. Alberto, David S. Paul, Aaron A. Cook, Paquita Nurden, Analia Sanchez Luceros, Alan T. Nurden, Wolfgang Bergmeier
Published 2018-01-01

APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis

by Simon Stritt, Paquita Nurden, Alan T. Nurden, Jean-François Schved, Jean-Claude Bordet, Maguelonne Roux, Marie-Christine Alessi, David-Alexandre Trégouët, Taija Mäkinen, Muriel Giansily-Blaizot
Published 2022-05-01

Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg2+ homeostasis and cytoskeletal architecture

by Simon Stritt, Paquita Nurden, Remi Favier, Marie Favier, Silvia Ferioli, Sanjeev K. Gotru, Judith M M. van Eeuwijk, Harald Schulze, Alan T. Nurden, Michele P. Lambert, Ernest Turro, Stephanie Burger-Stritt, Masayuki Matsushita, Lorenz Mittermeier, Paola Ballerini, Susanna Zierler, Michael A. Laffan, Vladimir Chubanov, Thomas Gudermann, Bernhard Nieswandt, Attila Braun
Published 2016-03-01

Germline variants in ETV6 underlie reduced platelet formation, platelet dysfunction and increased levels of circulating CD34+ progenitors

by Marjorie Poggi, Matthias Canault, Marie Favier, Ernest Turro, Paul Saultier, Dorsaf Ghalloussi, Veronique Baccini, Lea Vidal, Anna Mezzapesa, Nadjim Chelghoum, Badreddine Mohand-Oumoussa, Céline Falaise, Rémi Favier, Willem H. Ouwehand, Mathieu Fiore, Franck Peiretti, Pierre Emmanuel Morange, Noémie Saut, Denis Bernot, Andreas Greinacher, NIHR BioResource, Alan T. Nurden, Paquita Nurden, Kathleen Freson, David-Alexandre Trégouët, Hana Raslova, Marie-Christine Alessi
Published 2017-02-01

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

by Sebastian Dütting, Frederique Gaits-Iacovoni, David Stegner, Michael Popp, Adrien Antkowiak, Judith M.M. van Eeuwijk, Paquita Nurden, Simon Stritt, Tobias Heib, Katja Aurbach, Oguzhan Angay, Deya Cherpokova, Niels Heinz, Ayesha A. Baig, Maximilian G. Gorelashvili, Frank Gerner, Katrin G. Heinze, Jerry Ware, Georg Krohne, Zaverio M. Ruggeri, Alan T. Nurden, Harald Schulze, Ute Modlich, Irina Pleines, Cord Brakebusch, Bernhard Nieswandt
Published 2017-06-01

Germline variants in ETV6 underlie reduced platelet formation, platelet dysfunction and increased levels of circulating CD34+ progenitors.

by Poggi, Marjorie, Canault, Matthias, Favier, Marie, Turro, Ernest, Saultier, Paul, Ghalloussi, Dorsaf, Baccini, Veronique, Vidal, Lea, Mezzapesa, Anna, Chelghoum, Nadjim, Mohand-Oumoussa, Badreddine, Falaise, Céline, Favier, Rémi, Ouwehand, Willem H, Fiore, Mathieu, Peiretti, Franck, Morange, Pierre Emmanuel, Saut, Noémie, Bernot, Denis, Greinacher, Andreas, BioResource, Nihr, Nurden, Alan T, Nurden, Paquita, Freson, Kathleen, Trégouët, David-Alexandre, Raslova, Hana, Alessi, Marie-Christine
Published 2018

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.

by Simeoni, Ilenia, Stephens, Jonathan C, Hu, Fengyuan, Deevi, Sri VV, Megy, Karyn, Bariana, Tadbir K, Lentaigne, Claire, Schulman, Sol, Sivapalaratnam, Suthesh, Vries, Minka JA, Westbury, Sarah K, Greene, Daniel, Papadia, Sofia, Alessi, Marie-Christine, Attwood, Antony P, Ballmaier, Matthias, Baynam, Gareth, Bermejo, Emilse, Bertoli, Marta, Bray, Paul F, Bury, Loredana, Cattaneo, Marco, Collins, Peter, Daugherty, Louise C, Favier, Rémi, French, Deborah L, Furie, Bruce, Gattens, Michael, Germeshausen, Manuela, Ghevaert, Cedric, Goodeve, Anne C, Guerrero, Jose A, Hampshire, Daniel J, Hart, Daniel P, Heemskerk, Johan WM, Henskens, Yvonne MC, Hill, Marian, Hogg, Nancy, Jolley, Jennifer D, Kahr, Walter H, Kelly, Anne M, Kerr, Ron, Kostadima, Myrto, Kunishima, Shinji, Lambert, Michele P, Liesner, Ri, López, José A, Mapeta, Rutendo P, Mathias, Mary, Millar, Carolyn M, Nathwani, Amit, Neerman-Arbez, Marguerite, Nurden, Alan T, Nurden, Paquita, Othman, Maha, Peerlinck, Kathelijne, Perry, David J, Poudel, Pawan, Reitsma, Pieter, Rondina, Matthew T, Smethurst, Peter A, Stevenson, William, Szkotak, Artur, Tuna, Salih, van Geet, Christel, Whitehorn, Deborah, Wilcox, David A, Zhang, Bin, Revel-Vilk, Shoshana, Gresele, Paolo, Bellissimo, Daniel B, Penkett, Christopher J, Laffan, Michael A, Mumford, Andrew D, Rendon, Augusto, Gomez, Keith, Freson, Kathleen, Ouwehand, Willem H, Turro, Ernest
Published 2016