Surface plasmon resonance (SPR) sensors are the best optical sensors. They are very sensitive to a slight change in refractive index/dielectric constant at the interface of metal/dielectric materials. Gold and silver are the commonly used plasmonic materials. However, the materials show reasonable losses at some spectral range of interest. This paper presents the modeling and simulation of an SPR breathe acetone sensor based on tunable doped polyaniline-doped graphene composite at mid infrared range. Graphene has shown the capability of shrinking 3000nm wavelength of light to 54.7 nm with very negligible imaginary dielectric constant (0.43). The high negative effective dielectric constant of the polyaniline/graphene composite (-33.5) is very promising for developing SPR based sensing devices. The composite based SPR curve shows a promising SPR shift (almost 10°) due absorption of acetone vapour/exhale breathe acetone. It also shows better SPR curve features mid infrared spectral range compared to that of the gold and silver at visible range (Their optimum range). Therefore, this SPR sensor can realize the non-invasive, sensitive and selective detection of exhale breathe acetone for screening for diabetes at mid infrared range. © Published under licence by IOP Publishing Ltd.