Hydrotalcite is a double layered lamellar clay and is used as a catalyst precursor due to its structural properties. Hydrotalcite derived catalysts for hydrogen production through different processes have been reviewed. Recent developments of catalysts for hydrogen production are discussed accordingly. A brief introduction to structure and different synthesis routes of hydrotalcite based catalysts is also included. Article is focused on hydrotalcite derived catalysts consisting of different metals like Fe, Ni, Cu, Pt etc. and their performances in hydrogen production at different conditions. Use of such catalysts in hydrogen production process like steam reforming, sorption enhanced based generation, and various other applications is reviewed critically. Pros and cons of catalysts are discussed in detail. The scope and challenges in development of the hydrogen production process have been detailed out focusing modified hydrotalcite derived catalyst and process conditions. © 2017 Hydrogen Energy Publications LLC