The lithofacies characteristics, geochemical signals, and the trends of weathering indices of the Barremian-Danian strata of the Cauvery Basin, South India, record a synchronicity between relative sea level fluctuations as enforced by climatic cycles of varying durations, and the alternations of calcareous-siliciclastic deposition in tune with weathering in the source area. Occurrences of all the six third-order global sea level peaks, higher order cycles within these third-order cycles, absence of tectonic influence over depositional pattern except during Santonian, are all observed in this basin. Analyses of the stratigraphic variations of elemental concentrations and the trends of stable isotope, weathering indices, and other elemental ratios have revealed the prevalence of the coldest climate during Campanian and the warmest climate during Albian and Maastrichtian. Influence of alternating warm and cold climatic conditions over the weathering pattern in the provenance region and the influx of sediments to the depositional sites were also inferred from these data. However, aberrations and absence of perfect coupling between these alternations are also observed that owe allegiance to tectonic and other causes too. These inferences suggest that caution has to be exercised while interpreting chemostratigraphic signals from the long-duration strata. © 2015 Elsevier Inc. All rights reserved.