In this paper, a novel structure of multilayer organic photovoltaic cell has been designed and simulated. The integration of Poly(3-hexylthiophene-2,5-diyl) (P3HT) buffer layer and Poly(9,9-bis(3'-(N,N-dimethyl) N- ethylammoinium propyl-2,7-fluorene)-alt-2,7-(9,9 dioctyl fluorene)) dibromide (PFN:BR) electron transport layer (ETL) in the proposed solar cell has improved the performance significantly. The various performance measuring parameters like power conversion efficiency (PCE), short circuit current (Jsc), open circuit voltage (Voc), fill factor (FF), quantum efficiency (QE) have improved significantly. Furthermore, the effect of different layer thickness, the density of traps Nt and temperature on the proposed solar cell has been studied and the optimum value has been obtained. It has been observed that after optimizing the different parameters of the proposed structure, the performance measuring parameters shows an improvement of 14, 33.3, 200 and 300 in Voc FF, Jsc and PCE respectively over the reported organic solar cells. Further, a QE of about 90 is achieved in the proposed structure. © 2013 IEEE.