Ionic liquid-mediated ethosome for transdermal delivery of insulin

Nabila, F.H. and Islam, R. and Shimul, I.M. and Moniruzzaman, M. and Wakabayashi, R. and Kamiya, N. and Goto, M. (2024) Ionic liquid-mediated ethosome for transdermal delivery of insulin. Chemical Communications, 60 (30). pp. 4036-4039. ISSN 13597345

Full text not available from this repository.
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Herein, we report ethosome (ET) formulations composed of a safe amount of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC)-based ionic liquid with various concentrations of ethanol as a carrier for the transdermal delivery of a high molecular weight drug, insulin. The Insulin-loaded ET vesicles exhibited long-term stability compared to conventional DMPC ETs, showing significantly higher drug encapsulation efficiency and increased skin permeation ability. © 2024 The Royal Society of Chemistry.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: Controlled drug delivery; Ionic liquids; Targeted drug delivery, Dimyristoyl; Drug encapsulation efficiency; Ethosomes; High molecular weight; Long term stability; Phosphatidyl choline; Skin permeation; Transdermal delivery, Insulin, 1,2 dimyristoyl sn glycero 3 phosphatidylcholine; ethosome; insulin; ionic liquid; liposome; macrogol; nanoparticle; phosphatidylcholine; phospholipid; unclassified drug; dimyristoylphosphatidylcholine; drug; insulin, Article; cell viability; circular dichroism; confocal laser scanning microscopy; dispersity; drug delivery system; emulsion; encapsulation; molecular dynamics; molecular weight; particle size; phospholipid vesicle; photon correlation spectroscopy; spectrofluorometry; transmission electron microscopy; volatilization; X ray diffraction; zeta potential; cutaneous drug administration; skin, Administration, Cutaneous; Dimyristoylphosphatidylcholine; Insulin; Ionic Liquids; Liposomes; Pharmaceutical Preparations; Skin
Depositing User: Mr Ahmad Suhairi UTP
Date Deposited: 04 Jun 2024 14:19
Last Modified: 04 Jun 2024 14:19
URI: https://khub.utp.edu.my/scholars/id/eprint/19815

Actions (login required)

View Item
View Item