Nabila, F.H. and Islam, R. and Shimul, I.M. and Moniruzzaman, M. and Wakabayashi, R. and Kamiya, N. and Goto, M. (2024) Ionic liquid-mediated ethosome for transdermal delivery of insulin. Chemical Communications, 60 (30). pp. 4036-4039. ISSN 13597345
Full text not available from this repository.Abstract
Herein, we report ethosome (ET) formulations composed of a safe amount of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC)-based ionic liquid with various concentrations of ethanol as a carrier for the transdermal delivery of a high molecular weight drug, insulin. The Insulin-loaded ET vesicles exhibited long-term stability compared to conventional DMPC ETs, showing significantly higher drug encapsulation efficiency and increased skin permeation ability. © 2024 The Royal Society of Chemistry.
Item Type: | Article |
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Additional Information: | cited By 0 |
Uncontrolled Keywords: | Controlled drug delivery; Ionic liquids; Targeted drug delivery, Dimyristoyl; Drug encapsulation efficiency; Ethosomes; High molecular weight; Long term stability; Phosphatidyl choline; Skin permeation; Transdermal delivery, Insulin, 1,2 dimyristoyl sn glycero 3 phosphatidylcholine; ethosome; insulin; ionic liquid; liposome; macrogol; nanoparticle; phosphatidylcholine; phospholipid; unclassified drug; dimyristoylphosphatidylcholine; drug; insulin, Article; cell viability; circular dichroism; confocal laser scanning microscopy; dispersity; drug delivery system; emulsion; encapsulation; molecular dynamics; molecular weight; particle size; phospholipid vesicle; photon correlation spectroscopy; spectrofluorometry; transmission electron microscopy; volatilization; X ray diffraction; zeta potential; cutaneous drug administration; skin, Administration, Cutaneous; Dimyristoylphosphatidylcholine; Insulin; Ionic Liquids; Liposomes; Pharmaceutical Preparations; Skin |
Depositing User: | Mr Ahmad Suhairi UTP |
Date Deposited: | 04 Jun 2024 14:19 |
Last Modified: | 04 Jun 2024 14:19 |
URI: | https://khub.utp.edu.my/scholars/id/eprint/19815 |