Human health is important for many reasons, both at the individual and societal levels. It can affect the quality of life, productivity, education, healthcare costs, disease prevention and community well-being. To prevent the increasing fatalities caused by diabetes disease, early detection is needed. Ternary hybrid material is a promising material used as an active sensing material in metal oxide sensor (MOX). In this article, the ternary materials used are iron oxide, polyaniline (PANI) and reduced graphene oxide (RGO). In-situ method was used to hybridize these materials. The properties of the materials were characterized using thermogravimetry analysis (TGA), Fourier Transform Infrared analysis (FTIR), Field Emission Scanning Electron Microscopy (FESEM), High resolution Transmission Electron Microscopy (HRTEM) and gas sensing analysis for a humidity range of 50 to 90. TGA and FTIR show the characterization of all the singles' materials in the hybrid nanocomposite. FESEM and HRTEM reveal the microstructural of PANI embedded in iron oxide and RGO sheet. The gas sensing characterization shows the performance of the hybrid materials towards 1ppm of acetone at room temperature where the fastest response and recovery time were 29.42s and 19.93s at 60RH. © 2023 IEEE.