This chapter provides a detailed discussion on various renewable energy sources for desalination, and power system performance analysis by using hybrid systems. Water and energy are two essential components of human life that influence the growth and development of society. Renewable energy is becoming more popular as technology improves. Employing renewable energy sources has a number of drawbacks, the most significant of which is their unpredictability, which can be mitigated by using storage devices or combining them with other renewable energy sources. The prospects of imploring hybrid technologies for desalination is another aspect explored in this chapter. © 2022 John Wiley & Sons, Inc.