The use of Blockchain is becoming a matter of increasing importance, yet the software development industry has not given Blockchain adoption enough consideration. As a result of their inability to modify their software process within the project life cycle, many software development companies struggle to adopt Blockchain technology. This is because Blockchain Oriented Software (BOS) and its projects have distinctive characteristics that are distinct from traditional software and projects. The constructs and their items to adopt Blockchain in Software development industry have not been identified or investigated. This study aimed to identify technological, organizational, and environmental constructs and their items to adopt Blockchain. Utilizing a quantitative validation approach, 10 interviews and 25 assessment questionnaires were analyzed. The results reveal the identified technological, organizational, and environmental constructs and their items to adopt Blockchain. Experts unanimously agreed with Content Validity Ratio (CVR) results. According to most evaluation questionnaire forms and interview transcripts, the top technological construct was �Trialability� and the top organizational construct was �Cost� while the top environmental construct was �Market Dynamics.� All other constructs and their items were applicable, as indicated by most evaluation questionnaire forms and interview transcripts. This research gives a comprehensive list of technological, organizational, and environmental constructs and their items that demand the attention of Blockchain adoption researchers and industry players in the software development sector. © 2022 by the authors.