An effort has been made to simulation a compression ignition engine using hydrogen-diesel, hydrogen-diethyl ether, hydrogen-n-butanol and base diesel fuel as alternatives. The engine measured for the simulation is a single cylinder, four stroke, direct injection, diesel engine. During the simulation the injection timing and engine speed are kept constant at 23°bTDC and 1500 rpm. Diesel-RK, a piece of commercial software employed for this project, can forecast an engine emission, performance and combustion characteristics. The examination of the anticipated outcomes reveals that adding hydrogen to diesel leads in a small increase in efficiency and fuel consumption. With the usage of hydrogen-blend fuels, the majority of dangerous pollutants in exhaust are greatly decreased. The shortest ignition delay was consistently given by 5H295DEE. The lowest CO2 (578.61 g/kWh) was given by 5H295nB at CR 19.5. Hydrogen blends increase NOx emissions more than base diesel fuel. In the case of smoke and particulate matter emission, the reduce tendency was seen. © 2022 Hydrogen Energy Publications LLC