In this study, titanium dioxide nanoparticles were synthesized for possible application in enhanced oil recovery. Sol-gel method was employed with titanium(IV) isopropoxide as the precursor. The prepared materials were characterized using Powder X-Ray Diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM), High-Resolution Transmission electron microscopy (HRTEM) and Brunauer�Emmet�Teller (BET) techniques. Reaction parameter such as calcination temperature was varied during the preparation to obtain the uniform TiO2 nanoparticles with the smallest particle size and high surface area. The results of study revealed that 400C is the optimum calcination temperature in preparing TiO2 nanoparticles producing the smallest crystallite and particle sizes. XRD results indicated that the nanoparticles have formed anatase phase at 400C and achieved low crystallite size of 7.27 nm with the smallest average particle size of 19.53 nm through FESEM and HRTEM observations. BET analysis had achieved the highest surface area 103.64 m2/g. © 2019 Trans Tech Publications, Switzerland