The fluidized bed coating system is a conventional process of particles coating in various industries. In this work, an experimental investigation was conducted using Response Surface Methodology (RSM) to optimize the coating mass of particles in a top-spray fluidized bed coating. The design of experiments (DOEs) is a useful tool for controlling and optimization of products in industry. Thus, DOE was conducted using MINITAB software, version 16. This process used a sodium silicate solution for coating the sodium percarbonate particles. The effect of the fluidization air flow rate, atomization air flow rate and liquid flow rate on the coating mass in the top-spray fluidized bed coating was investigated. The experimental results indicated that the coating mass of particles is directly proportional to the liquid flow rate of the coating solution and inversely proportional to the air flow rate. It was demonstrated that the flow rate of the coating solution had the greatest influence on the coating efficiency. © 2017 Elsevier B.V.