Rescue of Recombinant Adenoviruses by CRISPR/Cas-Mediated in vivo Terminal Resolution

by André Riedl, Julian Fischer, Hans-Gerhard Burgert, Zsolt Ruzsics
Published 2022-03-01

Dominant-Negative Proteins in Herpesviruses – From Assigning Gene Function to Intracellular Immunization

by Zsolt Ruzsics, Ulrich H. Koszinowski, Hermine Mühlbach, Christian A. Mohr
Published 2009-10-01

Cytomegaloviruses and Macrophages—Friends and Foes From Early on?

by Sebastian Baasch, Sebastian Baasch, Zsolt Ruzsics, Philipp Henneke, Philipp Henneke
Published 2020-05-01

Expanding the Scope of Adenoviral Vectors by Utilizing Novel Tools for Recombination and Vector Rescue

by Julian Fischer, Ariana Fedotova, Clara Bühler, Laura Darriba, Sabrina Schreiner, Zsolt Ruzsics
Published 2024-04-01

A modified screening system for loss-of-function and dominant negative alleles of essential MCMV genes.

by Madlen Pogoda, Jens B Bosse, Karl-Klaus Conzelmann, Ulrich H Koszinowski, Zsolt Ruzsics
Published 2014-01-01

A Novel, Broad-Acting Peptide Inhibitor of Double-Stranded DNA Virus Gene Expression and Replication

by Zsolt Ruzsics, Zsolt Ruzsics, Zsolt Ruzsics, Katja Hoffmann, Katja Hoffmann, André Riedl, André Riedl, Adalbert Krawczyk, Adalbert Krawczyk, Marek Widera, Marek Widera, Helene Sertznig, Leonie Schipper, Valeria Kapper-Falcone, Valeria Kapper-Falcone, Valeria Kapper-Falcone, Monika Debreczeny, Wolfgang Ernst, Reingard Grabherr, Hartmut Hengel, Hartmut Hengel, Hartmut Hengel, Hanna Harant
Published 2020-11-01

Combining CRISPR-Cas-mediated terminal resolution with a novel genetic workflow to achieve high-diversity adenoviral libraries

by Julian Fischer, Ariana Fedotova, Lena Jaki, Erwan Sallard, Anja Erhardt, Jonas Fuchs, Zsolt Ruzsics
Published 2024-06-01

Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts.

by Linda Ebermann, Zsolt Ruzsics, Carlos A Guzmán, Nico van Rooijen, Rosaely Casalegno-Garduño, Ulrich Koszinowski, Luka Čičin-Šain
Published 2012-01-01

Nuclear Herpesvirus Capsid Motility Is Not Dependent on F-Actin

by Jens B. Bosse, Stina Virding, Stephan Y. Thiberge, Julian Scherer, Harald Wodrich, Zsolt Ruzsics, Ulrich H. Koszinowski, Lynn W. Enquist
Published 2014-10-01

A capsid-encoded PPxY-motif facilitates adenovirus entry.

by Harald Wodrich, Daniel Henaff, Baptist Jammart, Carolina Segura-Morales, Sigrid Seelmeir, Olivier Coux, Zsolt Ruzsics, Christopher M Wiethoff, Eric J Kremer
Published 2010-03-01

Membraneless Compartmentalization of Nuclear Assembly Sites during Murine Cytomegalovirus Infection

by Hana Mahmutefendić Lučin, Silvija Lukanović Jurić, Marina Marcelić, Igor Štimac, Ivona Viduka, Gordana Blagojević Zagorac, Berislav Lisnić, Zsolt Ruzsics, Pero Lučin
Published 2023-03-01

Cytomegalovirus downregulates IRE1 to repress the unfolded protein response.

by Sebastian Stahl, Julia M Burkhart, Florian Hinte, Boaz Tirosh, Hermine Mohr, René P Zahedi, Albert Sickmann, Zsolt Ruzsics, Matthias Budt, Wolfram Brune
Published 2013-01-01

Shedding light on the elusive role of endothelial cells in cytomegalovirus dissemination.

by Torsten Sacher, Joachim Andrassy, Aivars Kalnins, Lars Dölken, Stefan Jordan, Jürgen Podlech, Zsolt Ruzsics, Karl-Walter Jauch, Matthias J Reddehase, Ulrich H Koszinowski
Published 2011-11-01

Natural killer cells promote early CD8 T cell responses against cytomegalovirus.

by Scott H Robbins, Gilles Bessou, Amélie Cornillon, Nicolas Zucchini, Brigitte Rupp, Zsolt Ruzsics, Torsten Sacher, Elena Tomasello, Eric Vivier, Ulrich H Koszinowski, Marc Dalod
Published 2007-08-01

Transcriptional activation of the adenoviral genome is mediated by capsid protein VI.

by Sabrina Schreiner, Ruben Martinez, Peter Groitl, Fabienne Rayne, Remi Vaillant, Peter Wimmer, Guillaume Bossis, Thomas Sternsdorf, Lisa Marcinowski, Zsolt Ruzsics, Thomas Dobner, Harald Wodrich
Published 2012-02-01

Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo.

by Hermine Mohr, Christian A Mohr, Marlon R Schneider, Laura Scrivano, Barbara Adler, Simone Kraner-Schreiber, Angelika Schnieke, Maik Dahlhoff, Eckhard Wolf, Ulrich H Koszinowski, Zsolt Ruzsics
Published 2012-01-01

Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures

by Aleksei A. Stepanenko, Anastasiia O. Sosnovtseva, Marat P. Valikhov, Anastasia A. Chernysheva, Sergey A. Cherepanov, Gaukhar M. Yusubalieva, Zsolt Ruzsics, Anastasiia V. Lipatova, Vladimir P. Chekhonin
Published 2022-03-01

Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo.

by György Fejer, Lisa Drechsel, Jan Liese, Ulrike Schleicher, Zsolt Ruzsics, Nicola Imelli, Urs F Greber, Simone Keck, Bernd Hildenbrand, Anne Krug, Christian Bogdan, Marina A Freudenberg
Published 2008-11-01

Cytomegalovirus microRNAs facilitate persistent virus infection in salivary glands.

by Lars Dölken, Astrid Krmpotic, Sheila Kothe, Lee Tuddenham, Mélanie Tanguy, Lisa Marcinowski, Zsolt Ruzsics, Naama Elefant, Yael Altuvia, Hanah Margalit, Ulrich H Koszinowski, Stipan Jonjic, Sébastien Pfeffer
Published 2010-10-01

STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus

by Pia-Katharina Tegtmeyer, Julia Spanier, Katharina Borst, Jennifer Becker, André Riedl, Christoph Hirche, Luca Ghita, Jennifer Skerra, Kira Baumann, Stefan Lienenklaus, Marius Doering, Zsolt Ruzsics, Ulrich Kalinke
Published 2019-06-01