PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response

by Zdenek Andrysik, Kelly D. Sullivan, Jeffrey S. Kieft, Joaquin M. Espinosa
Published 2022-12-01

Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response

by Zdenek Andrysik, Heather Bender, Matthew D. Galbraith, Joaquin M. Espinosa
Published 2021-03-01

A Genetic Screen Identifies TCF3/E2A and TRIAP1 as Pathway-Specific Regulators of the Cellular Response to p53 Activation

by Zdenek Andrysik, Jihye Kim, Aik Choon Tan, Joaquín M. Espinosa
Published 2013-05-01

Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor that Induces CYP1A1 in Hepatic and Intestinal Cells

by Barbora Vyhlídalová, Kristýna Krasulová, Petra Pečinková, Karolína Poulíková, Radim Vrzal, Zdeněk Andrysík, Aneesh Chandran, Sridhar Mani, Zdenek Dvorak
Published 2020-04-01

Autophagy Controls the Kinetics and Extent of Mitochondrial Apoptosis by Regulating PUMA Levels

by Jacqueline Thorburn, Zdenek Andrysik, Leah Staskiewicz, Jacob Gump, Paola Maycotte, Andrew Oberst, Douglas R. Green, Joaquín M. Espinosa, Andrew Thorburn
Published 2014-04-01

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas

by Christopher G. Abraham, Michael P. Ludwig, Zdenek Andrysik, Ahwan Pandey, Molishree Joshi, Matthew D. Galbraith, Kelly D. Sullivan, Joaquin M. Espinosa
Published 2018-09-01

CDK8 Kinase Activity Promotes Glycolysis

by Matthew D. Galbraith, Zdenek Andrysik, Ahwan Pandey, Maria Hoh, Elizabeth A. Bonner, Amanda A. Hill, Kelly D. Sullivan, Joaquín M. Espinosa
Published 2017-11-01

Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells

by Martina Karasová, Jiřina Procházková, Zuzana Tylichová, Radek Fedr, Miroslav Ciganek, Miroslav Machala, Zdeněk Dvořák, Barbora Vyhlídalová, Iveta Zůvalová, Jiří Ehrmann, Jan Bouchal, Zdeněk Andrysík, Jan Vondráček
Published 2022-08-01

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

by Mary Ann Allen, Zdenek Andrysik, Veronica L Dengler, Hestia S Mellert, Anna Guarnieri, Justin A Freeman, Kelly D Sullivan, Matthew D Galbraith, Xin Luo, W Lee Kraus, Robin D Dowell, Joaquin M Espinosa
Published 2014-05-01

FAM193A is a positive regulator of p53 activity

by Maria M. Szwarc, Anna L. Guarnieri, Molishree Joshi, Huy N. Duc, Madison C. Laird, Ahwan Pandey, Santosh Khanal, Emily Dohm, Aimee K. Bui, Kelly D. Sullivan, Matthew D. Galbraith, Zdenek Andrysik, Joaquin M. Espinosa
Published 2023-03-01

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

by Kathryn D. Tuttle, Katherine A. Waugh, Paula Araya, Ross Minter, David J. Orlicky, Michael Ludwig, Zdenek Andrysik, Matthew A. Burchill, Beth A.J. Tamburini, Colin Sempeck, Keith Smith, Ross Granrath, Dayna Tracy, Jessica Baxter, Joaquin M. Espinosa, Kelly D. Sullivan
Published 2020-11-01