Metabolic Checkpoints in Differentiation of Helper T Cells in Tissue Inflammation

by Suyasha Roy, Zaigham Abbas Rizvi, Amit Awasthi
Published 2019-01-01

Evidence of CD1d pathway of lipid antigen presentation in mouse primary lung epithelial cells and its up-regulation upon Mycobacterium bovis BCG infection.

by Zaigham Abbas Rizvi, Niti Puri, Rajiv K Saxena
Published 2018-01-01

Evaluation of Ayush-64 (a Polyherbal Formulation) and Its Ingredients in the Syrian Hamster Model for SARS-CoV-2 Infection Reveals the Preventative Potential of <i>Alstonia scholar...

by Zaigham Abbas Rizvi, Upasna Madan, Manas Ranjan Tripathy, Sandeep Goswami, Shailendra Mani, Amit Awasthi, Madhu Dikshit
Published 2023-09-01

Pharmacological potential of Withania somnifera (L.) Dunal and Tinospora cordifolia (Willd.) Miers on the experimental models of COVID-19, T cell differentiation, and neutrophil fu...

by Zaigham Abbas Rizvi, Zaigham Abbas Rizvi, Prabhakar Babele, Upasna Madan, Upasna Madan, Srikanth Sadhu, Srikanth Sadhu, Manas Ranjan Tripathy, Manas Ranjan Tripathy, Sandeep Goswami, Sandeep Goswami, Shailendra Mani, Madhu Dikshit, Madhu Dikshit, Amit Awasthi, Amit Awasthi
Published 2023-03-01

Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis

by Zaigham Abbas Rizvi, Zaigham Abbas Rizvi, Prabhakar Babele, Srikanth Sadhu, Srikanth Sadhu, Upasna Madan, Upasna Madan, Manas Ranjan Tripathy, Manas Ranjan Tripathy, Sandeep Goswami, Sandeep Goswami, Shailendra Mani, Sachin Kumar, Amit Awasthi, Amit Awasthi, Madhu Dikshit, Madhu Dikshit
Published 2022-09-01

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

by Suyasha Roy, Zaigham Abbas Rizvi, Alexander J. Clarke, Felicity Macdonald, Abhaydeep Pandey, Dietmar Martin Werner Zaiss, Anna Kathrina Simon, Amit Awasthi
Published 2021-06-01

DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells

by Aamir Suhail, Zaigham Abbas Rizvi, Prabhakar Mujagond, Syed Azmal Ali, Preksha Gaur, Mukesh Singh, Vineet Ahuja, Amit Awasthi, Chittur Venkateshwaran Srikanth
Published 2019-12-01

Effect of Prophylactic Use of Intranasal Oil Formulations in the Hamster Model of COVID-19

by Zaigham Abbas Rizvi, Manas Ranjan Tripathy, Nishant Sharma, Sandeep Goswami, N Srikanth, J. L. N. Sastry, Shailendra Mani, Milan Surjit, Amit Awasthi, Madhu Dikshit
Published 2021-10-01

IL-9 aggravates SARS-CoV-2 infection and exacerbates associated airway inflammation

by Srikanth Sadhu, Rajdeep Dalal, Jyotsna Dandotiya, Akshay Binayke, Virendra Singh, Manas Ranjan Tripathy, Vinayaka Das, Sandeep Goswami, Shakti Kumar, Zaigham Abbas Rizvi, Amit Awasthi
Published 2023-07-01

Comparative Immunomodulatory Evaluation of the Receptor Binding Domain of the SARS-CoV-2 Spike Protein; a Potential Vaccine Candidate Which Imparts Potent Humoral and Th1 Type Immu...

by Tripti Shrivastava, Balwant Singh, Zaigham Abbas Rizvi, Rohit Verma, Sandeep Goswami, Preeti Vishwakarma, Kamini Jakhar, Sudipta Sonar, Shailendra Mani, Sankar Bhattacharyya, Amit Awasthi, Milan Surjit
Published 2021-05-01

Clinical and experimental evidence suggest omicron variant of SARS-CoV-2 is inherently less pathogenic than delta variant independent of previous immunity

by Ramachandran Thiruvengadam, Zaigham Abbas Rizvi, Sreevatsan Raghavan, Deepika Rathna Murugesan, Mudita Gosain, Jyotsna Dandotiya, Ayushi, Sweety Samal, Anil K. Pandey, Nitya Wadhwa, Shinjini Bhatnagar, Amit Awasthi, Pramod Kumar Garg
Published 2023-10-01

Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Based Novel Epitopes Induce Potent Immune Responses in vivo and Inhibit Viral Replication in vitro

by Preeti Vishwakarma, Naveen Yadav, Zaigham Abbas Rizvi, Naseem Ahmed Khan, Adarsh Kumar Chiranjivi, Shailendra Mani, Manish Bansal, Prabhanjan Dwivedi, Tripti Shrivastava, Rajesh Kumar, Amit Awasthi, Shubbir Ahmed, Sweety Samal
Published 2021-03-01

Gefitinib Results in Robust Host-Directed Immunity Against Salmonella Infection Through Proteo-Metabolomic Reprogramming

by Srikanth Sadhu, Zaigham Abbas Rizvi, Ramendra Pati Pandey, Rajdeep Dalal, Deepak Kumar Rathore, Bhoj Kumar, Manitosh Pandey, Yashwant Kumar, Renu Goel, Tushar K. Maiti, Atul Kumar Johri, Ashutosh Tiwari, Amit Kumar Pandey, Amit Awasthi
Published 2021-03-01

A Localized Chimeric Hydrogel Therapy Combats Tumor Progression through Alteration of Sphingolipid Metabolism

by Sanjay Pal, Nihal Medatwal, Sandeep Kumar, Animesh Kar, Varsha Komalla, Prabhu Srinivas Yavvari, Deepakkumar Mishra, Zaigham Abbas Rizvi, Shiv Nandan, Dipankar Malakar, Manoj Pillai, Amit Awasthi, Prasenjit Das, Ravi Datta Sharma, Aasheesh Srivastava, Sagar Sengupta, Ujjaini Dasgupta, Avinash Bajaj
Published 2019-10-01

Golden Syrian hamster as a model to study cardiovascular complications associated with SARS-CoV-2 infection

by Zaigham Abbas Rizvi, Rajdeep Dalal, Srikanth Sadhu, Akshay Binayke, Jyotsna Dandotiya, Yashwant Kumar, Tripti Shrivastava, Sonu Kumar Gupta, Suruchi Aggarwal, Manas Ranjan Tripathy, Deepak Kumar Rathore, Amit Kumar Yadav, Guruprasad R Medigeshi, Amit Kumar Pandey, Sweety Samal, Shailendra Asthana, Amit Awasthi
Published 2022-01-01

Omicron sub-lineage BA.5 infection results in attenuated pathology in hACE2 transgenic mice

by Zaigham Abbas Rizvi, Jyotsna Dandotiya, Srikanth Sadhu, Ritika Khatri, Janmejay Singh, Virendra Singh, Neeta Adhikari, Kritika Sharma, Vinayake Das, Amit Kumar Pandey, Bhabatosh Das, Guruprasad Medigeshi, Shalendra Mani, Shinjini Bhatnagar, Sweety Samal, Anil Kumar Pandey, Pramod Kumar Garg, Amit Awasthi
Published 2023-09-01

G4-binding drugs, chlorpromazine and prochlorperazine, repurposed against COVID-19 infection in hamsters

by Shuvra Shekhar Roy, Shuvra Shekhar Roy, Shalu Sharma, Shalu Sharma, Zaigham Abbas Rizvi, Dipanjali Sinha, Dipanjali Sinha, Divya Gupta, Mercy Rophina, Mercy Rophina, Paras Sehgal, Paras Sehgal, Srikanth Sadhu, Manas Ranjan Tripathy, Sweety Samal, Souvik Maiti, Souvik Maiti, Souvik Maiti, Vinod Scaria, Vinod Scaria, Sridhar Sivasubbu, Sridhar Sivasubbu, Amit Awasthi, Krishnan H. Harshan, Krishnan H. Harshan, Sanjeev Jain, Shantanu Chowdhury, Shantanu Chowdhury
Published 2023-03-01

A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 Delta variant.

by Nitin Hingankar, Suprit Deshpande, Payel Das, Zaigham Abbas Rizvi, Constantinos Kurt Wibmer, Poppy Mashilo, Mohammed Yousuf Ansari, Alison Burns, Shawn Barman, Fangzhu Zhao, Sohini Mukherjee, Jonathan L Torres, Souvick Chattopadhyay, Farha Mehdi, Jyoti Sutar, Deepak Kumar Rathore, Kamal Pargai, Janmejay Singh, Sudipta Sonar, Kamini Jakhar, Jyotsna Dandotiya, Sankar Bhattacharyya, Shailendra Mani, Sweety Samal, Savita Singh, Pallavi Kshetrapal, Ramachandran Thiruvengadam, Gaurav Batra, Guruprasad Medigeshi, Andrew B Ward, Shinjini Bhatnagar, Amit Awasthi, Devin Sok, Jayanta Bhattacharya
Published 2022-04-01

A broadly neutralizing monoclonal antibody overcomes the mutational landscape of emerging SARS-CoV-2 variants of concern.

by Hilal Ahmad Parray, Naveen Narayanan, Sonal Garg, Zaigham Abbas Rizvi, Tripti Shrivastava, Sachin Kushwaha, Janmejay Singh, Praveenkumar Murugavelu, Anbalagan Anantharaj, Farha Mehdi, Nisha Raj, Shivam Singh, Jyotsna Dandotiya, Asha Lukose, Deepti Jamwal, Sandeep Kumar, Adarsh K Chiranjivi, Samridhi Dhyani, Nitesh Mishra, Sanjeev Kumar, Kamini Jakhar, Sudipta Sonar, Anil Kumar Panchal, Manas Ranjan Tripathy, Shirlie Roy Chowdhury, Shubbir Ahmed, Sweety Samal, Shailendra Mani, Sankar Bhattacharyya, Supratik Das, Subrata Sinha, Kalpana Luthra, Gaurav Batra, Devinder Sehgal, Guruprasad R Medigeshi, Chandresh Sharma, Amit Awasthi, Pramod Kumar Garg, Deepak T Nair, Rajesh Kumar
Published 2022-12-01