Development of Multiple Cloning Site cis-Vectors for Recombinant Adeno-Associated Virus Production

by Yongping Yue, Dongsheng Duan
Published 2002-09-01

Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice.

by Dejia Li, Yongping Yue, Dongsheng Duan
Published 2010-12-01

100-fold but not 50-fold dystrophin overexpression aggravates electrocardiographic defects in the mdx model of Duchenne muscular dystrophy

by Yongping Yue, Nalinda B Wasala, Brian Bostick, Dongsheng Duan
Published 2016-01-01

Dystrophin R16/17-syntrophin PDZ fusion protein restores sarcolemmal nNOSμ

by Aman Patel, Junling Zhao, Yongping Yue, Keqing Zhang, Dongsheng Duan, Yi Lai
Published 2018-11-01

Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice.

by Dejia Li, Yi Lai, Yongping Yue, Peter S Rabinovitch, Chady Hakim, Dongsheng Duan
Published 2009-08-01

Dystrophin R16/17 protein therapy restores sarcolemmal nNOS in trans and improves muscle perfusion and function

by Junling Zhao, Hsiao Tung Yang, Lakmini Wasala, Keqing Zhang, Yongping Yue, Dongsheng Duan, Yi Lai
Published 2019-07-01

High-Resolution Histological Landscape of AAV DNA Distribution in Cellular Compartments and Tissues following Local and Systemic Injection

by Junling Zhao, Yongping Yue, Aman Patel, Lakmini Wasala, Jacob F. Karp, Keqing Zhang, Dongsheng Duan, Yi Lai
Published 2020-09-01

Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot.

by Kasun Kodippili, Lauren Vince, Jin-Hong Shin, Yongping Yue, Glenn E Morris, Mark A McIntosh, Dongsheng Duan
Published 2014-01-01

Systemic gene transfer reveals distinctive muscle transduction profile of tyrosine mutant AAV-1, -6, and -9 in neonatal dogs

by Chady H Hakim, Yongping Yue, Jin-Hong Shin, Regina R Williams, Keqing Zhang, Bruce F Smith, Dongsheng Duan
Published 2014-01-01

A novel genetic model provides a unique perspective on the relationship between postexercise glycogen concentration and increases in the abundance of key metabolic proteins after a...

by Seong Eun Kwak, Amy Zheng, Edward B Arias, Haiyan Wang, Xiufang Pan, Yongping Yue, Dongsheng Duan, Gregory D Cartee
Published 2024-01-01

SERCA2a overexpression improves muscle function in a canine Duchenne muscular dystrophy model

by Kasun Kodippili, Chady H. Hakim, Matthew J. Burke, Yongping Yue, James A. Teixeira, Keqing Zhang, Gang Yao, Gopal J. Babu, Roland W. Herzog, Dongsheng Duan
Published 2024-06-01

Dwarf Open Reading Frame (DWORF) Gene Therapy Ameliorated Duchenne Muscular Dystrophy Cardiomyopathy in Aged mdx Mice

by Emily D. Morales, Yongping Yue, Thais B. Watkins, Jin Han, Xiufang Pan, Aaron M. Gibson, Bryan Hu, Omar Brito‐Estrada, Gang Yao, Catherine A. Makarewich, Gopal J. Babu, Dongsheng Duan
Published 2023-02-01

A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy

by Chady H. Hakim, Nalinda B. Wasala, Xiufang Pan, Kasun Kodippili, Yongping Yue, Keqing Zhang, Gang Yao, Brittney Haffner, Sean X. Duan, Julian Ramos, Joel S. Schneider, N. Nora Yang, Jeffrey S. Chamberlain, Dongsheng Duan
Published 2017-09-01

Micro-dystrophin AAV Vectors Made by Transient Transfection and Herpesvirus System Are Equally Potent in Treating mdx Mouse Muscle Disease

by Chady H. Hakim, Nathalie Clément, Lakmini P. Wasala, Hsiao T. Yang, Yongping Yue, Keqing Zhang, Kasun Kodippili, Laura Adamson-Small, Xiufang Pan, Joel S. Schneider, N. Nora Yang, Jeffrey S. Chamberlain, Barry J. Byrne, Dongsheng Duan
Published 2020-09-01

Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice

by Ying Ann Chiao, Huiliang Zhang, Mariya Sweetwyne, Jeremy Whitson, Ying Sonia Ting, Nathan Basisty, Lindsay K Pino, Ellen Quarles, Ngoc-Han Nguyen, Matthew D Campbell, Tong Zhang, Matthew J Gaffrey, Gennifer Merrihew, Lu Wang, Yongping Yue, Dongsheng Duan, Henk L Granzier, Hazel H Szeto, Wei-Jun Qian, David Marcinek, Michael J MacCoss, Peter Rabinovitch
Published 2020-07-01

Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models

by Chady H. Hakim, Sandeep R. P. Kumar, Dennis O. Pérez-López, Nalinda B. Wasala, Dong Zhang, Yongping Yue, James Teixeira, Xiufang Pan, Keqing Zhang, Emily D. Million, Christopher E. Nelson, Samantha Metzger, Jin Han, Jacqueline A. Louderman, Florian Schmidt, Feng Feng, Dirk Grimm, Bruce F. Smith, Gang Yao, N. Nora Yang, Charles A. Gersbach, Shi-jie Chen, Roland W. Herzog, Dongsheng Duan
Published 2021-11-01