Modeling Inherited Cardiomyopathies in Adult Zebrafish for Precision Medicine

by Yonghe Ding, Yonghe Ding, Haisong Bu, Haisong Bu, Haisong Bu, Xiaolei Xu, Xiaolei Xu
Published 2020-11-01

Editorial: Model organisms and experimental models: opportunities and challenges in clinical and translational physiology

by Jaromir Myslivecek, Chi-Wen Lung, Tania Martins-Marques, Samuel T. Orange, Samuel T. Orange, Mikio Hiura, Yonghe Ding, Yonghe Ding
Published 2023-09-01

TMT-based quantitative proteomics analysis reveals the role of Notch signaling in FAdV-4-infected LMH cell

by Yujuan Niu, Zhiyang Liu, Mengyu Wang, Ke Du, Kaihui Chang, Yonghe Ding
Published 2022-09-01

Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy

by Yonghe Ding, Mingmin Wang, Haisong Bu, Jiarong Li, Xueying Lin, Xiaolei Xu
Published 2023-05-01

New-onset QT prolongation is a novel predictor of mortality in critically ill patients

by Yonghe Ding, Ryounghoon Jeon, Linyu Ran, Wenzhi Pan, Feilong Wang, Qiang Li
Published 2019-06-01

Using Zebrafish Animal Model to Study the Genetic Underpinning and Mechanism of Arrhythmogenic Cardiomyopathy

by Yujuan Niu, Yuanchao Sun, Yuting Liu, Ke Du, Xiaolei Xu, Yonghe Ding
Published 2023-02-01

Genome-wide investigation and expression profiling of LOR gene family in rapeseed under salinity and ABA stress

by Su Yang, Su Yang, Jialuo Chen, Yonghe Ding, Qian Huang, Guangna Chen, Zaid Ulhassan, Ji’an Wei, Jian Wang
Published 2023-05-01

Inhibition of mTOR or MAPK ameliorates vmhcl/myh7 cardiomyopathy in zebrafish

by Haisong Bu, Yonghe Ding, Jiarong Li, Ping Zhu, Yu-Huan Shih, Mingmin Wang, Yuji Zhang, Xueying Lin, Xiaolei Xu
Published 2021-12-01

TFEB Overexpression, Not mTOR Inhibition, Ameliorates RagC^S75Y Cardiomyopathy

by Maengjo Kim, Linghui Lu, Alexey V. Dvornikov, Xiao Ma, Yonghe Ding, Ping Zhu, Timothy M. Olson, Xueying Lin, Xiaolei Xu
Published 2021-05-01

Aging-associated sinus arrest and sick sinus syndrome in adult zebrafish.

by Jianhua Yan, Hongsong Li, Haisong Bu, Kunli Jiao, Alex X Zhang, Tai Le, Hung Cao, Yigang Li, Yonghe Ding, Xiaolei Xu
Published 2020-01-01

Lapatinib combined with doxorubicin causes dose-dependent cardiotoxicity partially through activating the p38MAPK signaling pathway in zebrafish embryos

by Ke Du, Yuting Liu, Lu Zhang, Lixia Peng, Wenjing Dong, Yajie Jiang, Mingming Niu, Yuanchao Sun, Chuanhong Wu, Yujuan Niu, Yonghe Ding
Published 2024-06-01

Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish.

by Xiaojing Sun, Tiffany Hoage, Ping Bai, Yonghe Ding, Zhenyue Chen, Ruilin Zhang, Wei Huang, Ashad Jahangir, Barry Paw, Yi-Gang Li, Xiaolei Xu
Published 2009-08-01

Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

by Yonghe Ding, Alexey V. Dvornikov, Xiao Ma, Hong Zhang, Yong Wang, Matthew Lowerison, Rene R. Packard, Lei Wang, Jun Chen, Yuji Zhang, Tzung Hsiai, Xueying Lin, Xiaolei Xu
Published 2019-10-01

Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy

by Yonghe Ding, Jingchun Yang, Peng Chen, Tong Lu, Kunli Jiao, David J. Tester, John R. Giudicessi, Kai Jiang, Michael J. Ackerman, Yigang Li, Dao Wu Wang, HoN‐chi Lee, Dao Wen Wang, Xiaolei Xu
Published 2020-09-01

Automated Segmentation of Light-Sheet Fluorescent Imaging to Characterize Experimental Doxorubicin-Induced Cardiac Injury and Repair

by René R. Sevag Packard, Kyung In Baek, Tyler Beebe, Nelson Jen, Yichen Ding, Feng Shi, Peng Fei, Bong Jin Kang, Po-Heng Chen, Jonathan Gau, Michael Chen, Jonathan Y. Tang, Yu-Huan Shih, Yonghe Ding, Debiao Li, Xiaolei Xu, Tzung K. Hsiai
Published 2017-08-01

A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene

by Yonghe Ding, Di Lang, Jianhua Yan, Haisong Bu, Hongsong Li, Kunli Jiao, Jingchun Yang, Haibo Ni, Stefano Morotti, Tai Le, Karl J Clark, Jenna Port, Stephen C Ekker, Hung Cao, Yuji Zhang, Jun Wang, Eleonora Grandi, Zhiqiang Li, Yongyong Shi, Yigang Li, Alexey V Glukhov, Xiaolei Xu
Published 2022-10-01

A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish

by Ankit Sabharwal, Jarryd M. Campbell, Tanya L. Schwab, Zachary WareJoncas, Mark D. Wishman, Hirotaka Ata, Wiebin Liu, Noriko Ichino, Danielle E. Hunter, Jake D. Bergren, Mark D. Urban, Rhianna M. Urban, Shannon R. Holmberg, Bibekananda Kar, Alex Cook, Yonghe Ding, Xiaolei Xu, Karl J. Clark, Stephen C. Ekker
Published 2022-07-01

Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality

by Ankit Sabharwal, Mark D Wishman, Roberto Lopez Cervera, MaKayla R Serres, Jennifer L Anderson, Shannon R Holmberg, Bibekananda Kar, Anthony J Treichel, Noriko Ichino, Weibin Liu, Jingchun Yang, Yonghe Ding, Yun Deng, Jean M Lacey, William J Laxen, Perry R Loken, Devin Oglesbee, Steven A Farber, Karl J Clark, Xiaolei Xu, Stephen C Ekker
Published 2022-11-01

Building the vertebrate codex using the gene breaking protein trap library

by Noriko Ichino, MaKayla R Serres, Rhianna M Urban, Mark D Urban, Anthony J Treichel, Kyle J Schaefbauer, Lauren E Tallant, Gaurav K Varshney, Kimberly J Skuster, Melissa S McNulty, Camden L Daby, Ying Wang, Hsin-kai Liao, Suzan El-Rass, Yonghe Ding, Weibin Liu, Jennifer L Anderson, Mark D Wishman, Ankit Sabharwal, Lisa A Schimmenti, Sridhar Sivasubbu, Darius Balciunas, Matthias Hammerschmidt, Steven Arthur Farber, Xiao-Yan Wen, Xiaolei Xu, Maura McGrail, Jeffrey J Essner, Shawn M Burgess, Karl J Clark, Stephen C Ekker
Published 2020-08-01

Cardiac Hypertrophy Involves both Myocyte Hypertrophy and Hyperplasia in Anemic Zebrafish

by Sun, Xiaojing, Hoage, Tiffany, Ding, Yonghe, Chen, Zhenyue, Zhang, Ruilin, Jahangir, Ashad, Xu, Xiaolei, Paw, Barry Htin, Bai, Ping, Huang, Wei, Li, Yi-Gang
Published 2013