An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells.

by Yingyun Cai, Shuiqing Yu, Xiaoli Chi, Sheli R Radoshitzky, Jens H Kuhn, Edward A Berger
Published 2021-01-01

Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro

by Yu-Jin Kim, Beatrice Cubitt, Yingyun Cai, Jens H. Kuhn, Daniel Vitt, Hella Kohlhof, Juan C. de la Torre
Published 2020-07-01

Correction: Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host...

by Masaharu Iwasaki, Petra Minder, Yíngyún Caì, Jens H Kuhn, John R Yates, Bruce E Torbett, Juan C de la Torre
Published 2020-01-01

Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factor...

by Masaharu Iwasaki, Petra Minder, Yíngyún Caì, Jens H Kuhn, John R Yates, Bruce E Torbett, Juan C de la Torre
Published 2018-02-01

EPS8 Facilitates Uncoating of Influenza A Virus

by Gloria P. Larson, Vy Tran, Shuǐqìng Yú, Yíngyún Caì, Christina A. Higgins, Danielle M. Smith, Steven F. Baker, Sheli R. Radoshitzky, Jens H. Kuhn, Andrew Mehle
Published 2019-11-01

A Novel Ebola Virus VP40 Matrix Protein-Based Screening for Identification of Novel Candidate Medical Countermeasures

by Ryan P. Bennett, Courtney L. Finch, Elena N. Postnikova, Ryan A. Stewart, Yingyun Cai, Shuiqing Yu, Janie Liang, Julie Dyall, Jason D. Salter, Harold C. Smith, Jens H. Kuhn
Published 2020-12-01

Scalable, Micro-Neutralization Assay for Assessment of SARS-CoV-2 (COVID-19) Virus-Neutralizing Antibodies in Human Clinical Samples

by Richard S. Bennett, Elena N. Postnikova, Janie Liang, Robin Gross, Steven Mazur, Saurabh Dixit, Gregory Kocher, Shuiqing Yu, Shalamar Georgia-Clark, Dawn Gerhardt, Yingyun Cai, Lindsay Marron, Vladimir V. Lukin, Michael R. Holbrook
Published 2021-05-01

Sangivamycin is highly effective against SARS-CoV-2 in vitro and has favorable drug properties

by Ryan P. Bennett, Elena N. Postnikova, Brett P. Eaton, Yingyun Cai, Shuiqing Yu, Charles O. Smith, Janie Liang, Huanying Zhou, Gregory A. Kocher, Michael J. Murphy, Harold C. Smith, Jens H. Kuhn
Published 2022-01-01

CD26/DPP4 cell-surface expression in bat cells correlates with bat cell susceptibility to Middle East respiratory syndrome coronavirus (MERS-CoV) infection and evolution of persist...

by Yíngyún Caì, Shu Qìng Yú, Elena N Postnikova, Steven Mazur, John G Bernbaum, Robin Burk, Téngfēi Zhāng, Sheli R Radoshitzky, Marcel A Müller, Ingo Jordan, Laura Bollinger, Lisa E Hensley, Peter B Jahrling, Jens H Kuhn
Published 2014-01-01

Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays

by Yíngyún Caì, Masaharu Iwasaki, Brett F. Beitzel, Shuīqìng Yú, Elena N. Postnikova, Beatrice Cubitt, Lisa Evans DeWald, Sheli R. Radoshitzky, Laura Bollinger, Peter B. Jahrling, Gustavo F. Palacios, Juan C. de la Torre, Jens H. Kuhn
Published 2018-11-01

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

by Aaron E. Lin, William E. Diehl, Yingyun Cai, Courtney L. Finch, Chidiebere Akusobi, Robert N. Kirchdoerfer, Laura Bollinger, Stephen F. Schaffner, Elizabeth A. Brown, Erica Ollmann Saphire, Kristian G. Andersen, Jens H. Kuhn, Jeremy Luban, Pardis C. Sabeti
Published 2020-01-01

Scalable, semi-automated fluorescence reduction neutralization assay for qualitative assessment of Ebola virus-neutralizing antibodies in human clinical samples.

by Elena N Postnikova, James Pettitt, Collin J Van Ryn, Michael R Holbrook, Laura Bollinger, Shuǐqìng Yú, Yíngyún Caì, Janie Liang, Michael C Sneller, Peter B Jahrling, Lisa E Hensley, Jens H Kuhn, Mosoka P Fallah, Richard S Bennett, Cavan Reilly
Published 2019-01-01

Specific Detection of Two Divergent Simian Arteriviruses Using RNAscope In Situ Hybridization.

by Shu Qìng Yú, Yíngyún Caì, Cassandra Lyons, Reed F Johnson, Elena Postnikova, Steven Mazur, Joshua C Johnson, Sheli R Radoshitzky, Adam L Bailey, Michael Lauck, Tony L Goldberg, David H O'Connor, Peter B Jahrling, Thomas C Friedrich, Jens H Kuhn
Published 2016-01-01

A Lassa Virus Live-Attenuated Vaccine Candidate Based on Rearrangement of the Intergenic Region

by Yingyun Cai, Masaharu Iwasaki, Daisuke Motooka, David X. Liu, Shuiqing Yu, Kurt Cooper, Randy Hart, Ricky Adams, Tracey Burdette, Elena N. Postnikova, Jonathan Kurtz, Marisa St. Claire, Chengjin Ye, Jens H. Kuhn, Luis Martínez-Sobrido, Juan Carlos de la Torre
Published 2020-04-01

A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene

by Yingyun Cai, Chengjin Ye, Benson Cheng, Aitor Nogales, Masaharu Iwasaki, Shuiqing Yu, Kurt Cooper, David X. Liu, Randy Hart, Ricky Adams, Tyler Brady, Elena N. Postnikova, Jonathan Kurtz, Marisa St Claire, Jens H. Kuhn, Juan Carlos de la Torre, Luis Martínez-Sobrido
Published 2020-02-01

Testing therapeutics in cell-based assays: Factors that influence the apparent potency of drugs.

by Elena Postnikova, Yu Cong, Lisa Evans DeWald, Julie Dyall, Shuiqing Yu, Brit J Hart, Huanying Zhou, Robin Gross, James Logue, Yingyun Cai, Nicole Deiuliis, Julia Michelotti, Anna N Honko, Richard S Bennett, Michael R Holbrook, Gene G Olinger, Lisa E Hensley, Peter B Jahrling
Published 2018-01-01

Development and Characterization of a cDNA-Launch Recombinant Simian Hemorrhagic Fever Virus Expressing Enhanced Green Fluorescent Protein: ORF 2b’ Is Not Required for In Vitro Vir...

by Yingyun Cai, Shuiqing Yu, Ying Fang, Laura Bollinger, Yanhua Li, Michael Lauck, Elena N. Postnikova, Steven Mazur, Reed F. Johnson, Courtney L. Finch, Sheli R. Radoshitzky, Gustavo Palacios, Thomas C. Friedrich, Tony L. Goldberg, David H. O’Connor, Peter B. Jahrling, Jens H. Kuhn
Published 2021-04-01

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry

by Yíngyún Caì, Shuǐqìng Yú, Rohit K. Jangra, Elena N. Postnikova, Jiro Wada, Robert B. Tesh, Sean P. J. Whelan, Michael Lauck, Michael R. Wiley, Courtney L. Finch, Sheli R. Radoshitzky, David H. O’Connor, Gustavo Palacios, Kartik Chandran, Charles Y. Chiu, Jens H. Kuhn
Published 2019-04-01

siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection.

by Sheli R Radoshitzky, Gianluca Pegoraro, Xi Olì Chī, Lián D Ng, Chih-Yuan Chiang, Lucas Jozwick, Jeremiah C Clester, Christopher L Cooper, Duane Courier, David P Langan, Knashka Underwood, Kathleen A Kuehl, Mei G Sun, Yíngyún Caì, Shu Qìng Yú, Robin Burk, Rouzbeh Zamani, Krishna Kota, Jens H Kuhn, Sina Bavari
Published 2016-03-01

Divergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques

by Victoria Wahl-Jensen, Joshua C. Johnson, Michael Lauck, Jason T. Weinfurter, Louise H. Moncla, Andrea M. Weiler, Olivia Charlier, Oscar Rojas, Russell Byrum, Dan R. Ragland, Louis Huzella, Erika Zommer, Melanie Cohen, John G. Bernbaum, Yíngyún Caì, Hannah B. Sanford, Steven Mazur, Reed F. Johnson, Jing Qin, Gustavo F. Palacios, Adam L. Bailey, Peter B. Jahrling, Tony L. Goldberg, David H. O’Connor, Thomas C. Friedrich, Jens H. Kuhn
Published 2016-03-01