Natural Syringyl Mediators Accelerate Laccase-Catalyzed β‑O‑4 Cleavage and Cα-Oxidation of a Guaiacyl Model Substrate via an Aggregation Mechanism

by Xu Chen, Xingyu Ouyang, Jiayi Li, Yi-Lei Zhao
Published 2021-08-01

A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments

by Xiao-Ling Li, Min-Juan Xu, Yi-Lei Zhao, Jun Xu
Published 2010-12-01

Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis

by Yuanqi Wang, Changsheng Zhang, Yi-Lei Zhao, Rosalinda Zhao, Kendall N. Houk
Published 2020-05-01

Insight into Structural Characteristics of Protein-Substrate Interaction in Pimaricin Thioesterase

by Shuobing Fan, Rufan Wang, Chen Li, Linquan Bai, Yi-Lei Zhao, Ting Shi
Published 2019-02-01

Examining asymmetric pairwise pre-reaction and transition states in enzymatic catalysis by molecular dynamics simulation and quantum mechanics/molecular mechanics calculation

by Shenggan Luo, Chu-Jun Lyu, Yong Mao, Yihan Liu, Ting Shi, Yi-Lei Zhao
Published 2023-06-01

Author Correction: Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity

by Qiang Huang, Ruohan Li, Tao Yi, Fengsong Cong, Dayong Wang, Zixin Deng, Yi-Lei Zhao
Published 2021-12-01

Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity

by Qiang Huang, Ruohan Li, Tao Yi, Fengsong Cong, Dayong Wang, Zixin Deng, Yi-Lei Zhao
Published 2021-11-01

Structure-guided insights into heterocyclic ring-cleavage catalysis of the non-heme Fe (II) dioxygenase NicX

by Gongquan Liu, Yi-Lei Zhao, Fangyuan He, Peng Zhang, Xingyu Ouyang, Hongzhi Tang, Ping Xu
Published 2021-02-01

Exploring the Interaction between Vancomycin/Teicoplanin and Receptor Binding Domain (RBD) of SARS-CoV-2

by Wen-Tao Tao, Qian Yu, Ya-Li Li, Mei Ge, Yi-Lei Zhao, Ting Shi
Published 2021-01-01

Reconstruction of kidney renal clear cell carcinoma evolution across pathological stages

by Shichao Pang, Yidi Sun, Leilei Wu, Liguang Yang, Yi-Lei Zhao, Zhen Wang, Yixue Li
Published 2018-02-01

Elucidation of Enzymatic Mechanism of Phenazine Biosynthetic Protein PhzF Using QM/MM and MD Simulations.

by Fei Liu, Yi-Lei Zhao, Xiaolei Wang, Hongbo Hu, Huasong Peng, Wei Wang, Jing-Fang Wang, Xuehong Zhang
Published 2015-01-01

Origin of the Unexpected Enantioselectivity in the Enzymatic Reductions of 5-Membered-Ring Heterocyclic Ketones Catalyzed by <i>Candida parapsilosis</i> Carbonyl Reductases

by Byu Ri Sim, Jie Gu, Yvette Ley, Shenggan Luo, Yihan Liu, Qin Chen, Yao Nie, Yi-Lei Zhao
Published 2022-09-01

Evolutionary coupling-inspired engineering of alcohol dehydrogenase reveals the influence of distant sites on its catalytic efficiency for stereospecific synthesis of chiral alcoho...

by Jie Gu, Byu Ri Sim, Jiarui Li, Yangqing Yu, Lei Qin, Lunjie Wu, Yu Shen, Yao Nie, Yi-Lei Zhao, Yan Xu
Published 2021-01-01

Structural basis for the recognition of sulfur in phosphorothioated DNA

by Guang Liu, Wencheng Fu, Zhenyi Zhang, Yao He, Hao Yu, Yuli Wang, Xiaolei Wang, Yi-Lei Zhao, Zixin Deng, Geng Wu, Xinyi He
Published 2018-11-01

Bilateral Posterior Uveitis and Retinal Detachment During Immunotherapy: A Case Report and Literature Review

by Ling Peng, Ling Peng, Qi-Qi Mao, Bo Jiang, Jin Zhang, Yi-Lei Zhao, Xiao-Dong Teng, Jin-Song Yang, Yang Xia, Shi-Qing Chen, Justin Stebbing, Hai Jiang
Published 2020-11-01

Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis

by Jun Xu, Song-Lin Yang, Zhi-Gang Zhang, Ping Ao, Wen-Han Lin, Dong Liu, Zhen-Hao Xu, Xiao-Meng Lang, Yi-Lei Zhao, Min-Juan Xu, Xiao-Jin Liu
Published 2012-03-01

Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics

by Wan-Hong Wen, Yue Zhang, Ying-Ying Zhang, Qian Yu, Chu-Chu Jiang, Man-Cheng Tang, Jin-Yue Pu, Lian Wu, Yi-Lei Zhao, Ting Shi, Jiahai Zhou, Gong-Li Tang
Published 2021-12-01

HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells

by Wen-Fang Wang, Li Yan, Zhao Liu, Lan-Xuan Liu, Jian Lin, Zhi-Yin Liu, Xiong-Ping Chen, Wu Zhang, Zi-Zhen Xu, Ting Shi, Jun-Min Li, Yi-Lei Zhao, Guoyu Meng, Yi Xia, Jian-Yong Li, Jiang Zhu
Published 2017-08-01

Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis.

by Wang, Yuanqi, Zhang, Changsheng, Zhao, Yi-Lei, Zhao, Rosalinda, Houk, Kendall N
Published 2020