NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

by Heidi M. Britton, Adrian B. Levine, Yaoqing Shen, Karen Mungall, Jonathan Serrano, Matija Snuderl, Erin Pleasance, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Shahrad R. Rassekh, Rebecca Deyell, Stephen Yip, Sylvia Cheng, Chris Dunham
Published 2021-03-01

Slow Off-Rate Modified Aptamer (SOMAmer) Proteomic Analysis of Patient-Derived Malignant Glioma Identifies Distinct Cellular Proteomes

by Thatchawan Thanasupawat, Aleksandra Glogowska, Christopher Pascoe, Sai Nivedita Krishnan, Maliha Munir, Farhana Begum, Jason Beiko, Jerry Krcek, Marc R. Del Bigio, Marshall Pitz, Yaoqing Shen, Victor Spicer, Kevin M. Coombs, John Wilkins, Sabine Hombach-Klonisch, Thomas Klonisch
Published 2021-09-01

O35: Parent-of-origin-aware genomic analysis infers segregation of pathogenic variants in SDHD without parental data*

by Kasmintan Schrader, Vahid Akbari, Vincent Hanlon, Katherine Dixon, Kieran O’Neill, Yaoqing Shen, Alshanee Sharma, Janine Senz, Yanni Wang, Daniel Chan, Alexandra Fok, Quan Hong, Jennifer Nuk, Dean Regier, Alice Virani, Louis Lefebvre, Fabio Feldman, Marco Marra, Sophie Sun, Stephen Yip, Peter Lansdorp, Steven Jones
Published 2023-01-01

Personalized oncogenomics: clinical experience with malignant peritoneal mesothelioma using whole genome sequencing.

by Brandon S Sheffield, Anna V Tinker, Yaoqing Shen, Harry Hwang, Hector H Li-Chang, Erin Pleasance, Carolyn Ch'ng, Amy Lum, Julie Lorette, Yarrow J McConnell, Sophie Sun, Steven J M Jones, Allen M Gown, David G Huntsman, David F Schaeffer, Andrew Churg, Stephen Yip, Janessa Laskin, Marco A Marra
Published 2015-01-01

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.

by Alice L Yuan, Christian B Ricks, Alexandra K Bohm, Xueqing Lun, Lori Maxwell, Shahana Safdar, Shazreh Bukhari, Amanda Gerber, Wajid Sayeed, Elizabeth A Bering, Haley Pedersen, Jennifer A Chan, Yaoqing Shen, Marco Marra, David R Kaplan, Warren Mason, Lindsey D Goodman, Ravesanker Ezhilarasan, Ascher B Kaufmann, Matthew Cabral, Steve M Robbins, Donna L Senger, Daniel P Cahill, Erik P Sulman, J Gregory Cairncross, Michael D Blough
Published 2018-01-01

P658: Detection of variant parent-of-origin in diverse hereditary cancer syndromes using only the proband’s blood sample

by Kasmintan Schrader, Vahid Akbari, Vincent Hanlon, Tiffany Leung, Katherine Dixon, Kieran O’Neill, Alexandra Roston, Lilian Cordova, Karen Wong, Alshanee Sharma, Yaoqing Shen, Janine Senz, Yanni Wang, Daniel Chan, Alexandra Fok, Quan Hong, Jennifer Nuk, Robin Coope, Eric Chuah, Simon Chan, Hyun-Wu Lee, Steve Bilobram, Yongjun Zhao, Miruna Bala, Karen Mungall, Andy Mungall, Richard Moore, Dean Regier, Alice Virani, Louis Lefebvre, Fabio Feldman, Marco Marra, Sophie Sun, Stephen Yip, Peter Lansdorp, Steven Jones
Published 2024-01-01

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma

by Ana Nikolic, Francesca Maule, Anna Bobyn, Katrina Ellestad, Seungil Paik, Sajid A. Marhon, Parinaz Mehdipour, Xueqing Lun, Huey-Miin Chen, Claire Mallard, Alexander J. Hay, Michael J. Johnston, Christopher J. Gafuik, Franz J. Zemp, Yaoqing Shen, Nicoletta Ninkovic, Katalin Osz, Elodie Labit, N. Daniel Berger, Duncan K. Brownsey, John J. Kelly, Jeff Biernaskie, Peter B. Dirks, Darren J. Derksen, Steven J. M. Jones, Donna L. Senger, Jennifer A. Chan, Douglas J. Mahoney, Daniel D. De Carvalho, Marco Gallo
Published 2023-05-01

Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers

by Rebecca J. Deyell, Yaoqing Shen, Emma Titmuss, Katherine Dixon, Laura M. Williamson, Erin Pleasance, Jessica M. T. Nelson, Sanna Abbasi, Martin Krzywinski, Linlea Armstrong, Melika Bonakdar, Carolyn Ch’ng, Eric Chuah, Chris Dunham, Alexandra Fok, Martin Jones, Anna F. Lee, Yussanne Ma, Richard A. Moore, Andrew J. Mungall, Karen L. Mungall, Paul C. Rogers, Kasmintan A. Schrader, Alice Virani, Kathleen Wee, Sean S. Young, Yongjun Zhao, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Shahrad R. Rassekh
Published 2024-05-01

Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

by Astrid De Boeck, Bo Young Ahn, Charlotte D’Mello, Xueqing Lun, Shyam V. Menon, Mana M. Alshehri, Frank Szulzewsky, Yaoqing Shen, Lubaba Khan, Ngoc Ha Dang, Elliott Reichardt, Kimberly-Ann Goring, Jennifer King, Cameron J. Grisdale, Natalie Grinshtein, Dolores Hambardzumyan, Karlyne M. Reilly, Michael D. Blough, J. Gregory Cairncross, V. Wee Yong, Marco A. Marra, Steven J. M. Jones, David R. Kaplan, Kathy D. McCoy, Eric C. Holland, Pinaki Bose, Jennifer A. Chan, Stephen M. Robbins, Donna L. Senger
Published 2020-10-01

The impact of whole genome and transcriptome analysis (WGTA) on predictive biomarker discovery and diagnostic accuracy of advanced malignancies

by Basile Tessier‐Cloutier, Jasleen K Grewal, Martin R Jones, Erin Pleasance, Yaoqing Shen, Ellen Cai, Chris Dunham, Lynn Hoang, Basil Horst, David G Huntsman, Diana Ionescu, Anthony N Karnezis, Anna F Lee, Cheng Han Lee, Tae Hoon Lee, David DW Twa, Andrew J Mungall, Karen Mungall, Julia R Naso, Tony Ng, David F Schaeffer, Brandon S Sheffield, Brian Skinnider, Tyler Smith, Laura Williamson, Ellia Zhong, Dean A Regier, Janessa Laskin, Marco A Marra, C Blake Gilks, Steven JM Jones, Stephen Yip
Published 2022-07-01