Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony

by Che-Wei Chang, Mark D. Evans, Xinxing Yu, Gui-Qiu Yu, Lennart Mucke
Published 2021-10-01

Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models

by Melanie Das, Wenjie Mao, Eric Shao, Soniya Tamhankar, Gui-Qiu Yu, Xinxing Yu, Kaitlyn Ho, Xin Wang, Jiaming Wang, Lennart Mucke
Published 2021-11-01

Neuronal levels and sequence of tau modulate the power of brain rhythms

by Melanie Das, Sumihiro Maeda, Bozhong Hu, Gui-Qiu Yu, Weikun Guo, Isabel Lopez, Xinxing Yu, Chao Tai, Xin Wang, Lennart Mucke
Published 2018-09-01

Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models

by Melanie Das, Wenjie Mao, Yuliya Voskobiynyk, Deanna Necula, Irene Lew, Cathrine Petersen, Allie Zahn, Gui-Qiu Yu, Xinxing Yu, Nicholas Smith, Faten A. Sayed, Li Gan, Jeanne T. Paz, Lennart Mucke
Published 2023-10-01

Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer’s disease mutations but not by...

by Erik C. B. Johnson, Kaitlyn Ho, Gui-Qiu Yu, Melanie Das, Pascal E. Sanchez, Biljana Djukic, Isabel Lopez, Xinxing Yu, Michael Gill, Weiping Zhang, Jeanne T. Paz, Jorge J. Palop, Lennart Mucke
Published 2020-09-01

Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony.

by Chang, Che-Wei, Evans, Mark, Yu, Xinxing, Yu, Gui-Qiu, Mucke, Lennart
Published 2021

Spring-Like Pseudoelectroelasticity of Monocrystalline Cu2S Nanowire.

by Zhang, Qiubo, Shi, Zhe, Yin, Kuibo, Dong, Hui, Xu, Feng, Peng, Xinxing, Yu, Kaihao, Zhang, Hongtao, Chen, Chia-Chin, Valov, Ilia, Zheng, Haimei, Sun, Litao
Published 2018