Clinical trials of R-(-)-gossypol (AT-101) in newly diagnosed and recurrent glioblastoma: NABTT 0602 and NABTT 0702.

by John B Fiveash, Xiaobu Ye, David M Peerboom, Tom Mikkelsen, Sajeel Chowdhary, Myrna Rosenfeld, Glenn J Lesser, Joy Fisher, Serena Desideri, Stuart Grossman, Lance Leopold, Louis B Nabors
Published 2024-01-01

The effect of an adenosine A2A agonist on intra-tumoral concentrations of temozolomide in patients with recurrent glioblastoma

by Sadhana Jackson, Jon Weingart, Edjah K. Nduom, Thura T. Harfi, Richard T. George, Dorothea McAreavey, Xiaobu Ye, Nicole M. Anders, Cody Peer, William D. Figg, Mark Gilbert, Michelle A. Rudek, Stuart A. Grossman
Published 2018-01-01

Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model.

by Zineb Belcaid, Jillian A Phallen, Jing Zeng, Alfred P See, Dimitrios Mathios, Chelsea Gottschalk, Sarah Nicholas, Meghan Kellett, Jacob Ruzevick, Christopher Jackson, Emilia Albesiano, Nicholas M Durham, Xiaobu Ye, Phuoc T Tran, Betty Tyler, John W Wong, Henry Brem, Drew M Pardoll, Charles G Drake, Michael Lim
Published 2014-01-01

Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system

by Russell Maxwell, Andrew S. Luksik, Tomas Garzon-Muvdi, Alice L. Hung, Eileen S. Kim, Adela Wu, Yuanxuan Xia, Zineb Belcaid, Noah Gorelick, John Choi, Debebe Theodros, Christopher M. Jackson, Dimitrios Mathios, Xiaobu Ye, Phuoc T. Tran, Kristin J. Redmond, Henry Brem, Drew M. Pardoll, Lawrence R. Kleinberg, Michael Lim
Published 2018-12-01

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

by Alice L. Hung, Russell Maxwell, Debebe Theodros, Zineb Belcaid, Dimitrios Mathios, Andrew S. Luksik, Eileen Kim, Adela Wu, Yuanxuan Xia, Tomas Garzon-Muvdi, Christopher Jackson, Xiaobu Ye, Betty Tyler, Mark Selby, Alan Korman, Bryan Barnhart, Su-Myeong Park, Je-In Youn, Tamrin Chowdhury, Chul-Kee Park, Henry Brem, Drew M. Pardoll, Michael Lim
Published 2018-08-01

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

by Christina Jackson, Ada Tam, Sarah Harris-Bookman, Brian Francica, Charles G. Drake, Drew M. Pardoll, Debebe Theodros, Esteban Velarde, Betty Tyler, Xiaobu Ye, Henry Brem, Mark Selby, Dimitrios Mathios, Mira A. Patel, Jennifer E. Kim, Christina M. Kochel, Thomas R. Nirschl, Ali Ghasemzadeh, Christopher C. Jackson, Phuoc T. Tran, Vladimir Coric, Michael Lim
Published 2016-06-01

Efficacy and Biomarker Study of Bevacizumab for Hearing Loss Resulting From Neurofibromatosis Type 2–Associated Vestibular Schwannomas

by Blakeley, Jaishri O., Ye, Xiaobu, Duda, Dan Gabriel, Halpin, Chris F., Bergner, Amanda L., Muzikansky, Alona, Merker, Vanessa, Gerstner, Elizabeth Robins, Fayad, Laura M., Ahlawat, Shivani, Jacobs, Michael A., Jain, Rakesh K., Zalewski, Christopher, Dombi, Eva, Widemann, Brigitte C., Plotkin, Scott Randall
Published 2017