Cerebral Malaria in Mouse and Man

by Nazanin Ghazanfari, Nazanin Ghazanfari, Scott N. Mueller, Scott N. Mueller, William R. Heath, William R. Heath
Published 2018-09-01

Resident Memory T Cells and Their Role within the Liver

by Sonia Ghilas, Ana-Maria Valencia-Hernandez, Matthias H. Enders, William R. Heath, Daniel Fernandez-Ruiz
Published 2020-11-01

Multiple dendritic cell populations activate CD4+ T cells after viral stimulation.

by Adele M Mount, Christopher M Smith, Fiona Kupresanin, Kristina Stoermer, William R Heath, Gabrielle T Belz
Published 2008-02-01

Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity

by Angela D. Pack, Patrick V. Schwartzhoff, Zeb R. Zacharias, Daniel Fernandez-Ruiz, William R. Heath, Prajwal Gurung, Kevin L. Legge, Chris J. Janse, Noah S. Butler
Published 2021-08-01

High expression of CD38 and MHC class II on CD8+ T cells during severe influenza disease reflects bystander activation and trogocytosis

by Xiaoxiao Jia, Brendon Y Chua, Liyen Loh, Marios Koutsakos, Lukasz Kedzierski, Moshe Olshansky, William R Heath, So Young Chang, Jianqing Xu, Zhongfang Wang, Katherine Kedzierska
Published 2021-01-01

Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1.

by Bethany L Macleod, Sammy Bedoui, Jyh Liang Hor, Scott N Mueller, Tiffany A Russell, Natasha A Hollett, William R Heath, David C Tscharke, Andrew G Brooks, Thomas Gebhardt
Published 2014-08-01

IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection.

by Catherine Q Nie, Nicholas J Bernard, M Ursula Norman, Fiona H Amante, Rachel J Lundie, Brendan S Crabb, William R Heath, Christian R Engwerda, Michael J Hickey, Louis Schofield, Diana S Hansen
Published 2009-04-01

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

by Nicholas Collins, Xiaodong Jiang, Ali Zaid, Bethany L. Macleod, Jane Li, Chang Ook Park, Ashraful Haque, Sammy Bedoui, William R. Heath, Scott N. Mueller, Thomas S. Kupper, Thomas Gebhardt, Francis R. Carbone
Published 2016-05-01

T Cell Help Amplifies Innate Signals in CD8+ DCs for Optimal CD8+ T Cell Priming

by Marie Greyer, Paul G. Whitney, Angus T. Stock, Gayle M. Davey, Christina Tebartz, Annabell Bachem, Justine D. Mintern, Richard A. Strugnell, Stephen J. Turner, Thomas Gebhardt, Meredith O’Keeffe, William R. Heath, Sammy Bedoui
Published 2016-01-01

A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs

by Kieran English, Rain Kwan, Lauren E. Holz, Claire McGuffog, Jelte M. M. Krol, Daryan Kempe, Tsuneyasu Kaisho, William R. Heath, Leszek Lisowski, Maté Biro, Geoffrey W. McCaughan, David G. Bowen, Patrick Bertolino
Published 2024-02-01

Infection Programs Sustained Lymphoid Stromal Cell Responses and Shapes Lymph Node Remodeling upon Secondary Challenge

by Julia L. Gregory, Anne Walter, Yannick O. Alexandre, Jyh Liang Hor, Ruijie Liu, Joel Z. Ma, Sapna Devi, Nobuko Tokuda, Yuji Owada, Laura K. Mackay, Gordon K. Smyth, William R. Heath, Scott N. Mueller
Published 2017-01-01

Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity.

by Fionna A Surette, Jenna J Guthmiller, Lei Li, Alexandria J Sturtz, Rahul Vijay, Rosemary L Pope, Brandon L McClellan, Angela D Pack, Ryan A Zander, Peng Shao, Linda Yu-Ling Lan, Daniel Fernandez-Ruiz, William R Heath, Patrick C Wilson, Noah S Butler
Published 2021-02-01

Differential location of NKT and MAIT cells within lymphoid tissue

by Darryl N. Johnson, Zheng Ruan, Emma V. Petley, Sapna Devi, Lauren E. Holz, Adam P. Uldrich, Jeffrey Y. W. Mak, Jyh Liang Hor, Scott N. Mueller, James McCluskey, David P. Fairlie, Phillip K. Darcy, Paul A. Beavis, William R. Heath, Dale I. Godfrey
Published 2022-03-01

Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression

by Mitra Ashayeripanah, Javier Vega-Ramos, Daniel Fernandez-Ruiz, Shirin Valikhani, Aaron T.L. Lun, Jason T. White, Louise J. Young, Atefeh Yaftiyan, Yifan Zhan, Linda Wakim, Irina Caminschi, Mireille H. Lahoud, Andrew M. Lew, Ken Shortman, Gordon K. Smyth, William R. Heath, Justine D. Mintern, Antoine Roquilly, Jose A. Villadangos
Published 2024-02-01

Caenorhabditis elegans processes sensory information to choose between freeloading and self-defense strategies

by Jodie A Schiffer, Francesco A Servello, William R Heath, Francis Raj Gandhi Amrit, Stephanie V Stumbur, Matthias Eder, Olivier MF Martin, Sean B Johnsen, Julian A Stanley, Hannah Tam, Sarah J Brennan, Natalie G McGowan, Abigail L Vogelaar, Yuyan Xu, William T Serkin, Arjumand Ghazi, Nicholas Stroustrup, Javier Apfeld
Published 2020-05-01

CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

by Lauren E. Holz, Julia E. Prier, David Freestone, Thiago M. Steiner, Kieran English, Darryl N. Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M. Davey, Dale I. Godfrey, Katsuyuki Yui, Laura K. Mackay, Mireille H. Lahoud, Irina Caminschi, Geoffrey I. McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz, William R. Heath
Published 2018-10-01

Plasmodium berghei Hsp90 contains a natural immunogenic I-Ab-restricted antigen common to rodent and human Plasmodium species

by Matthias H. Enders, Ganchimeg Bayarsaikhan, Sonia Ghilas, Yu Cheng Chua, Rose May, Maria N. de Menezes, Zhengyu Ge, Peck Szee Tan, Anton Cozijnsen, Vanessa Mollard, Katsuyuki Yui, Geoffrey I. McFadden, Mireille H. Lahoud, Irina Caminschi, Anthony W. Purcell, Ralf B. Schittenhelm, Lynette Beattie, William R. Heath, Daniel Fernandez-Ruiz
Published 2021-01-01

Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells

by Anna H. Mooney, Sarah L. Draper, Olivia K. Burn, Regan J. Anderson, Benjamin J. Compton, Chingwen Tang, Kathryn J. Farrand, Pietro Di Lucia, Micol Ravà, Valeria Fumagalli, Leonardo Giustini, Elisa Bono, Dale I. Godfrey, William R. Heath, Weiming Yuan, Francis V. Chisari, Luca G. Guidotti, Matteo Iannacone, John Sidney, Alessandro Sette, Shivali A. Gulab, Gavin F. Painter, Ian F. Hermans
Published 2024-05-01

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria.

by Lei Shong Lau, Daniel Fernandez-Ruiz, Vanessa Mollard, Angelika Sturm, Michelle A Neller, Anton Cozijnsen, Julia L Gregory, Gayle M Davey, Claerwen M Jones, Yi-Hsuan Lin, Ashraful Haque, Christian R Engwerda, Catherine Q Nie, Diana S Hansen, Kenneth M Murphy, Anthony T Papenfuss, John J Miles, Scott R Burrows, Tania de Koning-Ward, Geoffrey I McFadden, Francis R Carbone, Brendan S Crabb, William R Heath
Published 2014-05-01

Human Nasal Epithelium Organoids for Assessing Neutralizing Antibodies to a Protective SARS-CoV-2 Virus-like Particle Vaccine

by Julio Carrera Montoya, Simon Collett, Daniel Fernandez Ruiz, Linda Earnest, Melissa A. Edeling, Ashley Huey Yiing Yap, Chinn Yi Wong, James P. Cooney, Kathryn C. Davidson, Jason Roberts, Steven Rockman, Bang M. Tran, Julie L. McAuley, Georgia Deliyannis, Samantha L. Grimley, Damian F. J. Purcell, Shafagh A. Waters, Dale I. Godfrey, Dhiraj Hans, Marc Pellegrini, Jason M. Mackenzie, Elizabeth Vincan, William R. Heath, Joseph Torresi
Published 2024-02-01