Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study.

by Patrick Linsel-Nitschke, Anika Götz, Jeanette Erdmann, Ingrid Braenne, Peter Braund, Christian Hengstenberg, Klaus Stark, Marcus Fischer, Stefan Schreiber, Nour Eddine El Mokhtari, Arne Schaefer, Jürgen Schrezenmeir, Diana Rubin, Anke Hinney, Thomas Reinehr, Christian Roth, Jan Ortlepp, Peter Hanrath, Alistair S Hall, Massimo Mangino, Wolfgang Lieb, Claudia Lamina, Iris M Heid, Angela Doering, Christian Gieger, Annette Peters, Thomas Meitinger, H-Erich Wichmann, Inke R König, Andreas Ziegler, Florian Kronenberg, Nilesh J Samani, Heribert Schunkert, Wellcome Trust Case Control Consortium (WTCCC), Cardiogenics Consortium
Published 2008-08-01

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

by Eilis Hannon, Emma L Dempster, Georgina Mansell, Joe Burrage, Nick Bass, Marc M Bohlken, Aiden Corvin, Charles J Curtis, David Dempster, Marta Di Forti, Timothy G Dinan, Gary Donohoe, Fiona Gaughran, Michael Gill, Amy Gillespie, Cerisse Gunasinghe, Hilleke E Hulshoff, Christina M Hultman, Viktoria Johansson, René S Kahn, Jaakko Kaprio, Gunter Kenis, Kaarina Kowalec, James MacCabe, Colm McDonald, Andrew McQuillin, Derek W Morris, Kieran C Murphy, Colette J Mustard, Igor Nenadic, Michael C O'Donovan, Diego Quattrone, Alexander L Richards, Bart PF Rutten, David St Clair, Sebastian Therman, Timothea Toulopoulou, Jim Van Os, John L Waddington, Wellcome Trust Case Control Consortium (WTCCC), CRESTAR consortium, Patrick Sullivan, Evangelos Vassos, Gerome Breen, David Andrew Collier, Robin M Murray, Leonard S Schalkwyk, Jonathan Mill
Published 2021-02-01

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study.

by Hernandez-Fuentes, Maria P, Franklin, Christopher, Rebollo-Mesa, Irene, Mollon, Jennifer, Delaney, Florence, Perucha, Esperanza, Stapleton, Caragh, Borrows, Richard, Byrne, Catherine, Cavalleri, Gianpiero, Clarke, Brendan, Clatworthy, Menna, Feehally, John, Fuggle, Susan, Gagliano, Sarah A, Griffin, Sian, Hammad, Abdul, Higgins, Robert, Jardine, Alan, Keogan, Mary, Leach, Timothy, MacPhee, Iain, Mark, Patrick B, Marsh, James, Maxwell, Peter, McKane, William, McLean, Adam, Newstead, Charles, Augustine, Titus, Phelan, Paul, Powis, Steve, Rowe, Peter, Sheerin, Neil, Solomon, Ellen, Stephens, Henry, Thuraisingham, Raj, Trembath, Richard, Topham, Peter, Vaughan, Robert, Sacks, Steven H, Conlon, Peter, Opelz, Gerhard, Soranzo, Nicole, Weale, Michael E, Lord, Graham M, United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3
Published 2018

Parallelization of logic regression analysis on SNP-SNP interactions of a Crohn’s disease dataset model

by Unitsa Sangket, Surakameth Mahasirimongkol, Pichaya Tandayya, Surasak Sangkhathat, Wasun Chantratita, Qi, Liu, Yasui, Yutaka
Published 2017

Rheumatoid arthritis association at 6q23.

by Thomson, W, Barton, A, Ke, X, Eyre, S, Hinks, A, Bowes, J, Donn, R, Symmons, D, Hider, S, Bruce, I, Wilson, A, Marinou, I, Morgan, A, Emery, P, Carter, A, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Strachan, D, Worthington, J
Published 2016

Coanalysis of GWAS with eQTLs reveals disease-tissue associations.

by Kang, Hyunseok Peter, Morgan, Alex A, Chen, Rong, Schadt, Eric E, Butte, Atul J
Published 2012

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

by Todd, J, Walker, N, Cooper, J, Smyth, D, Downes, K, Plagnol, V, Bailey, R, Nejentsev, S, Field, S, Payne, F, Lowe, C, Szeszko, J, Hafler, J, Zeitels, L, Yang, J, Vella, A, Nutland, S, Stevens, H, Schuilenburg, H, Coleman, G, Maisuria, M, Meadows, W, Smink, L, Healy, B, Burren, O
Published 2016

The histone demethylase JARID1A is associated with susceptibility to ankylosing spondylitis.

by Pointon, J, Harvey, D, Karaderi, T, Appleton, L, Farrar, C, Wordsworth, B
Published 2016

The histone demethylase JARID1A is associated with susceptibility to ankylosing spondylitis.

by Pointon, J, Harvey, D, Karaderi, T, Appleton, L, Farrar, C, Wordsworth, B
Published 2016

Human genetic evidence for involvement of CD137 in atherosclerosis.

by Söderström, L, Gertow, K, Folkersen, L, Sabater-Lleal, M, Sundman, E, Sheikine, Y, Goel, A, Baldassarre, D, Humphries, SE, de Faire, U, Watkins, H, Tremoli, E, Veglia, F, Hamsten, A, Hansson, G, Olofsson, P
Published 2016

Genome-wide association scan allowing for epistasis in type 2 diabetes.

by Bell, J, Timpson, N, Rayner, N, Zeggini, E, Frayling, T, Hattersley, A, Morris, A, McCarthy, M
Published 2016

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility.

by Barton, A, Thomson, W, Ke, X, Eyre, S, Hinks, A, Bowes, J, Gibbons, L, Plant, D, Wilson, A, Marinou, I, Morgan, A, Emery, P, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Worthington, J
Published 2016

Bayesian and frequentist methods and analyses of genome-wide association studies

by Vukcevic, D
Published 2016

Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.

by Athanasiadis, G, Sabater-Lleal, M, Buil, A, Souto, J, Borrell, M, Lathrop, M, Watkins, H, Almasy, L, Hamsten, A, Soria, J
Published 2016

Model selection strategies in genome-wide association studies

by Keildson, S
Published 2016

Genetic susceptibility to common mycobacterial diseases

by Wong, H
Published 2016

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.

by Burr, M, Naseem, H, Hinks, A, Eyre, S, Gibbons, L, Bowes, J, Wilson, A, Maxwell, J, Morgan, A, Emery, P, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Thomson, W, Worthington, J, Barton, A
Published 2016

Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach.

by Perry, JR, McCarthy, M, Hattersley, A, Zeggini, E, Weedon, M, Frayling, T
Published 2016

Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease.

by Beckly, J, Hancock, L, Geremia, A, Cummings, JR, Morris, A, Cooney, R, Pathan, S, Guo, C, Jewell, D
Published 2016

Efficient Software for Multi-marker, Region-Based Analysis of GWAS Data.

by Sanjak, Jaleal S, Long, Anthony D, Thornton, Kevin R
Published 2016