A ΔclpB mutant of Francisella tularensis subspecies holarctica strain, FSC200, is a more effective live vaccine than F. tularensis LVS in a mouse respiratory challenge model of tul...

by Igor Golovliov, Susan M Twine, Hua Shen, Anders Sjostedt, Wayne Conlan
Published 2013-01-01

Molecular immune responses to aerosol challenge with Francisella tularensis in mice inoculated with live vaccine candidates of varying efficacy.

by Hua Shen, Gregory Harris, Wangxue Chen, Anders Sjostedt, Patrik Ryden, Wayne Conlan
Published 2010-10-01

Roles for wbtC, wbtI, and kdtA Genes in Lipopolysaccharide Biosynthesis, Protein Glycosylation, Virulence, and Immunogenicity in Francisella tularensis Strain SCHU S4

by Susan M. Twine, Evguenii Vinogradov, Helena Lindgren, Anders Sjostedt, J. Wayne Conlan
Published 2012-09-01

Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model.

by Konstantin Kadzhaev, Carl Zingmark, Igor Golovliov, Mark Bolanowski, Hua Shen, Wayne Conlan, Anders Sjöstedt
Published 2009-01-01

Lymphotoxin-α Plays Only a Minor Role in Host Resistance to Respiratory Infection with Virulent Type A Francisella tularensis in Mice

by Deng Zhang, Rhonda KuoLee, Greg Harris, Qinxian Zhang, J. Wayne Conlan, Wangxue Chen
Published 2008-01-01

An in vitro co-culture mouse model demonstrates efficient vaccine-mediated control of Francisella tularensis SCHU S4 and identifies nitric oxide as a predictor of efficacy

by Igor Golovlev, Helena Lindgren, Kjell Eneslätt, Wayne Conlan, Amandine Mosnier, Thomas Henry, Anders Sjöstedt
Published 2016-11-01

Novel Transcriptional and Translational Biomarkers of Tularemia Vaccine Efficacy in a Mouse Inhalation Model: Proof of Concept

by Qing Yan Liu, Sonia Leclerc, Youlian Pan, Ziying Liu, Felicity Stark, Joseph Wayne Conlan
Published 2021-12-01

Immunoproteomics analysis of the murine antibody response to vaccination with an improved Francisella tularensis live vaccine strain (LVS).

by Susan M Twine, Mireille D Petit, Kelly M Fulton, Robert V House, J Wayne Conlan
Published 2010-04-01

Zika virus crosses an in vitro human blood brain barrier model

by Judie B. Alimonti, Maria Ribecco-Lutkiewicz, Caroline Sodja, Anna Jezierski, Danica B. Stanimirovic, Qing Liu, Arsalan S. Haqqani, Wayne Conlan, Mahmud Bani-Yaghoub
Published 2018-05-01

Modern Development and Production of a New Live Attenuated Bacterial Vaccine, SCHU S4 <em>ΔclpB</em>, to Prevent Tularemia

by J. Wayne Conlan, Anders Sjöstedt, H. Carl Gelhaus, Perry Fleming, Kevan McRae, Ronald R. Cobb, Roberto De Pascalis, Karen L. Elkins
Published 2021-06-01

Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis

by Roberto De Pascalis, Blake Frey, Helen M. Rice, Varunika Bhargava, Terry H. Wu, Ross L. Peterson, J. Wayne Conlan, Anders Sjöstedt, Karen L. Elkins
Published 2022-08-01

Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence.

by Mélanie Rigard, Jeanette E Bröms, Amandine Mosnier, Maggy Hologne, Amandine Martin, Lena Lindgren, Claire Punginelli, Claire Lays, Olivier Walker, Alain Charbit, Philippe Telouk, Wayne Conlan, Laurent Terradot, Anders Sjöstedt, Thomas Henry
Published 2016-09-01