Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus.

by Vincent Pedergnana, Mohamed Abdel-Hamid, Julien Guergnon, Amira Mohsen, Lénaïg Le Fouler, Ioannis Theodorou, Mostafa Kamal Mohamed, Arnaud Fontanet, Sabine Plancoulaine, Laurent Abel
Published 2012-01-01

Combined linkage and association studies show that HLA class II variants control levels of antibodies against Epstein-Barr virus antigens.

by Vincent Pedergnana, Laurène Syx, Aurélie Cobat, Julien Guergnon, Pauline Brice, Christophe Fermé, Patrice Carde, Olivier Hermine, Catherine Le-Pendeven, Corinne Amiel, Yassine Taoufik, Alexandre Alcaïs, Ioannis Theodorou, Caroline Besson, Laurent Abel
Published 2014-01-01

Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure

by David A. Smith, Carlota Fernandez-Antunez, Andrea Magri, Rory Bowden, Nimisha Chaturvedi, Jacques Fellay, John McLauchlan, Graham R. Foster, William L. Irving, STOP-HCV Consortium, Peter Simmonds, Vincent Pedergnana, Santseharay Ramirez, Jens Bukh, Eleanor Barnes, M. Azim Ansari
Published 2021-10-01

Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the...

by Frédégonde About, Tiphaine Oudot-Mellakh, Jonathan Niay, Pascaline Rabiéga, Vincent Pedergnana, Darragh Duffy, Philippe Sultanik, Carole Cagnot, Fabrice Carrat, Patrick Marcellin, Fabien Zoulim, Dominique Larrey, Christophe Hézode, Hélène Fontaine, Jean-Pierre Bronowicki, Stanislas Pol, Matthew L Albert, Ioannis Theodorou, Aurélie Cobat, Laurent Abel, ANRS CO20-CUPIC study group
Published 2015-01-01

Utility of a buccal swab point-of-care test for the IFNL4 genotype in the era of direct acting antivirals for hepatitis C virus.

by Aminata Sy, Leanne McCabe, Emma Hudson, Azim M Ansari, Vincent Pedergnana, Shang-Kuan Lin, S Santana, Marzia Fiorino, Aftab Ala, Ben Stone, M Smith, Mark Nelson, Stephen T Barclay, Stuart McPherson, Stephen D Ryder, Jane Collier, Eleanor Barnes, Ann Sarah Walker, Sarah L Pett, Graham Cooke, STOP-HCV-1 trial team
Published 2023-01-01

Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome

by Michaela Lucas, Pooja Deshpande, Ian James, Andri Rauch, Katja Pfafferott, Elouise Gaylard, Shahzma Merani, Anne Plauzolles, Andrew Lucas, Wyatt McDonnell, Spyros Kalams, Mark Pilkinton, Cody Chastain, Louise Barnett, Amy Prosser, Simon Mallal, Karen Fitzmaurice, Heidi Drummer, M. Azim Ansari, Vincent Pedergnana, Ellie Barnes, Mina John, Dermot Kelleher, Paul Klenerman, Silvana Gaudieri
Published 2018-05-01

Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

by M Azim Ansari, Elihu Aranday-Cortes, Camilla LC Ip, Ana da Silva Filipe, Siu Hin Lau, Connor Bamford, David Bonsall, Amy Trebes, Paolo Piazza, Vattipally Sreenu, Vanessa M Cowton, STOP-HCV Consortium, Emma Hudson, Rory Bowden, Arvind H Patel, Graham R Foster, William L Irving, Kosh Agarwal, Emma C Thomson, Peter Simmonds, Paul Klenerman, Chris Holmes, Eleanor Barnes, Chris CA Spencer, John McLauchlan, Vincent Pedergnana
Published 2019-09-01

The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis

by Hamish Innes, Hans Dieter Nischalke, Indra Neil Guha, Karl Heinz Weiss, Will Irving, Daniel Gotthardt, Eleanor Barnes, Janett Fischer, M. Azim Ansari, Jonas Rosendahl, Shang‐Kuan Lin, Astrid Marot, Vincent Pedergnana, Markus Casper, Jennifer Benselin, Frank Lammert, John McLauchlan, Philip L. Lutz, Victoria Hamill, Sebastian Mueller, Joanne R. Morling, Georg Semmler, Florian Eyer, Johann von Felden, Alexander Link, Arndt Vogel, Jens U. Marquardt, Stefan Sulk, Jonel Trebicka, Luca Valenti, Christian Datz, Thomas Reiberger, Clemens Schafmayer, Thomas Berg, Pierre Deltenre, Jochen Hampe, Felix Stickel, Stephan Buch
Published 2022-05-01