FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro

by Hwee Hui Lau, Nur Shabrina Amirruddin, Larry Sai Weng Loo, Jun Wei Chan, Elhadi Iich, Vidhya Gomathi Krishnan, Shawn Hoon, Adrian Kee Keong Teo
Published 2023-08-01

TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae

by Mohammad Alfatah, Jin Huei Wong, Vidhya Gomathi Krishnan, Yong Cheow Lee, Quan Feng Sin, Corinna Jie Hui Goh, Kiat Whye Kong, Wei Ting Lee, Jacqueline Lewis, Shawn Hoon, Prakash Arumugam
Published 2021-05-01

HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells

by Natasha Hui Jin Ng, Joanita Binte Jasmen, Chang Siang Lim, Hwee Hui Lau, Vidhya Gomathi Krishnan, Juned Kadiwala, Rohit N. Kulkarni, Helge Ræder, Ludovic Vallier, Shawn Hoon, Adrian Kee Keong Teo
Published 2019-06-01

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells

by Blaise Su Jun Low, Chang Siang Lim, Shirley Suet Lee Ding, Yaw Sing Tan, Natasha Hui Jin Ng, Vidhya Gomathi Krishnan, Su Fen Ang, Claire Wen Ying Neo, Chandra S. Verma, Shawn Hoon, Su Chi Lim, E. Shyong Tai, Adrian Kee Keong Teo
Published 2021-05-01