Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Nondividing Cells: from Yeast to the Mammalian Brain

by Edoardo Parrella, Valter D. Longo
Published 2010-01-01

Exploring juventology: unlocking the secrets of youthspan and longevity programs

by Sebastian Brandhorst, Valter D. Longo
Published 2024-04-01

Metabolites and Immune Response in Tumor Microenvironments

by Salvatore Cortellino, Valter D. Longo
Published 2023-07-01

Yeast Chronological Lifespan: Longevity Regulatory Genes and Mechanisms

by Mario G. Mirisola, Valter D. Longo
Published 2022-05-01

A fasting-mimicking diet and vitamin C: turning anti-aging strategies against cancer

by Maira Di Tano, Valter D. Longo
Published 2020-09-01

Intermittent and Periodic Fasting, Hormones, and Cancer Prevention

by Giulia Salvadori, Mario Giuseppe Mirisola, Valter D. Longo
Published 2021-09-01

Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.

by Mario G Mirisola, Giusi Taormina, Paola Fabrizio, Min Wei, Jia Hu, Valter D Longo
Published 2014-02-01

Significant and systematic expression differentiation in long-lived yeast strains.

by Chao Cheng, Paola Fabrizio, Huanying Ge, Min Wei, Valter D Longo, Lei M Li
Published 2007-10-01

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9.

by Min Wei, Paola Fabrizio, Jia Hu, Huanying Ge, Chao Cheng, Lei Li, Valter D Longo
Published 2008-01-01

Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension.

by Min Wei, Paola Fabrizio, Federica Madia, Jia Hu, Huanying Ge, Lei M Li, Valter D Longo
Published 2009-05-01

Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.

by Paola Fabrizio, Shawn Hoon, Mehrnaz Shamalnasab, Abdulaye Galbani, Min Wei, Guri Giaever, Corey Nislow, Valter D Longo
Published 2010-07-01

Fasting enhances the response of glioma to chemo- and radiotherapy.

by Fernando Safdie, Sebastian Brandhorst, Min Wei, Weijun Wang, Changhan Lee, Saewon Hwang, Peter S Conti, Thomas C Chen, Valter D Longo
Published 2012-01-01

Fasting-Mimicking Diet Inhibits Autophagy and Synergizes with Chemotherapy to Promote T-Cell-Dependent Leukemia-Free Survival

by Roberta Buono, Jonathan Tucci, Raffaello Cutri, Novella Guidi, Serghei Mangul, Franca Raucci, Matteo Pellegrini, Steven D. Mittelman, Valter D. Longo
Published 2023-12-01

Autophagy in blood cancers: biological role and therapeutic implications

by Alessio Nencioni, Michele Cea, Fabrizio Montecucco, Valter D. Longo, Franco Patrone, Angelo M. Carella, Tessa L. Holyoake, G. Vignir Helgason
Published 2013-09-01

Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers

by Maira Di Tano, Franca Raucci, Claudio Vernieri, Irene Caffa, Roberta Buono, Maura Fanti, Sebastian Brandhorst, Giuseppe Curigliano, Alessio Nencioni, Filippo de Braud, Valter D. Longo
Published 2020-05-01

Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology

by Priya Rangan, Inyoung Choi, Min Wei, Gerardo Navarrete, Esra Guen, Sebastian Brandhorst, Nobel Enyati, Gab Pasia, Daral Maesincee, Vanessa Ocon, Maya Abdulridha, Valter D. Longo
Published 2019-03-01

Six-month periodic fasting does not affect somatosensory nerve function in type 2 diabetes patients

by Zoltan Kender, Zoltan Kender, Ekaterina von Rauchhaupt, Ekaterina von Rauchhaupt, Daniel Schwarz, Dimitrios Tsilingiris, Dimitrios Tsilingiris, Lukas Schimpfle, Lukas Schimpfle, Hannelore Bartl, Valter D. Longo, Valter D. Longo, Martin Bendszus, Stefan Kopf, Stefan Kopf, Stephan Herzig, Stephan Herzig, Stephan Herzig, Stephan Herzig, Sabine Heiland, Julia Szendroedi, Julia Szendroedi, Julia Szendroedi, Alba Sulaj, Alba Sulaj
Published 2023-05-01

Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy.

by Stefano Di Biase, Hong Seok Shim, Kyung Hwa Kim, Manlio Vinciguerra, Francesca Rappa, Min Wei, Sebastian Brandhorst, Francesco Cappello, Hamed Mirzaei, Changhan Lee, Valter D Longo
Published 2017-03-01

Correction: Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy.

by Stefano Di Biase, Hong Seok Shim, Kyung Hwa Kim, Manlio Vinciguerra, Francesca Rappa, Min Wei, Sebastian Brandhorst, Francesco Cappello, Hamed Mirzaei, Changhan Lee, Valter D Longo
Published 2017-05-01

A Comparison of the Impact of Restrictive Diets on the Gastrointestinal Tract of Mice

by András Gregor, Laura Huber, Sandra Auernigg-Haselmaier, Felix Sternberg, Magdalena Billerhart, Andreas Dunkel, Veronika Somoza, Manfred Ogris, Barbara Kofler, Valter D. Longo, Jürgen König, Kalina Duszka
Published 2022-07-01