Bayesian ¹³C-Metabolic Flux Analysis of Parallel Tracer Experiments in Granulocytes: A Directional Shift within the Non-Oxidative Pentose Phosphate Pathway Supports Phag...

by Melanie Hogg, Eva-Maria Wolfschmitt, Ulrich Wachter, Fabian Zink, Peter Radermacher, Josef Albert Vogt
Published 2023-12-01

Ex Vivo ¹³C-Metabolic Flux Analysis of Porcine Circulating Immune Cells Reveals Cell Type-Specific Metabolic Patterns and Sex Differences in the Pentose Phosphate Pathwa...

by Melanie Hogg, Eva-Maria Wolfschmitt, Ulrich Wachter, Fabian Zink, Peter Radermacher, Josef Albert Vogt
Published 2024-01-01

Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock

by Tamara Merz, Josef A. Vogt, Ulrich Wachter, Enrico Calzia, Csaba Szabo, Rui Wang, Peter Radermacher, Oscar McCook
Published 2017-06-01

Metabolic substrate utilization in stress-induced immune cells

by Xiaomin Zhang, Fabian Zink, Felix Hezel, Josef Vogt, Ulrich Wachter, Martin Wepler, Maurizio Loconte, Christine Kranz, Andreas Hellmann, Boris Mizaikoff, Peter Radermacher, Clair Hartmann
Published 2020-12-01

Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat

by Maja Dziegelewska, Susanne Holtze, Christiane Vole, Ulrich Wachter, Uwe Menzel, Michaela Morhart, Marco Groth, Karol Szafranski, Arne Sahm, Christoph Sponholz, Philip Dammann, Klaus Huse, Thomas Hildebrandt, Matthias Platzer
Published 2016-08-01

Effects of Sodium Thiosulfate During Resuscitation From Trauma-and-Hemorrhage in Cystathionine-γ-Lyase Knockout Mice With Diabetes Type 1

by Michael Gröger, Melanie Hogg, Essam Abdelsalam, Sandra Kress, Andrea Hoffmann, Bettina Stahl, Enrico Calzia, Ulrich Wachter, Josef A. Vogt, Rui Wang, Tamara Merz, Tamara Merz, Peter Radermacher, Oscar McCook
Published 2022-04-01

Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle

by Ulrich Stifel, Eva-Maria Wolfschmitt, Josef Vogt, Ulrich Wachter, Sabine Vettorazzi, Daniel Tews, Melanie Hogg, Fabian Zink, Nora Maria Koll, Sandra Winning, Rémi Mounier, Bénédicte Chazaud, Peter Radermacher, Pamela Fischer-Posovszky, Giorgio Caratti, Jan Tuckermann
Published 2022-03-01

Cigarette smoke exposure reduces hemorrhagic shock induced circulatory dysfunction in mice with attenuated glucocorticoid receptor function

by Martin Wepler, Martin Wepler, Jonathan M. Preuss, Cornelia Tilp, Martina Keck, Jochen Blender, Ulrich Wachter, Tamara Merz, Josef Vogt, Sandra Kress, Michael Gröger, Andrea Hoffmann, Marina Fink, Enrico Calzia, Ute Burret, Peter Radermacher, Jan P. Tuckermann, Sabine Vettorazzi
Published 2022-09-01

Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction

by Martin Wepler, Martin Wepler, Jonathan M. Preuss, Tamara Merz, Clair Hartmann, Clair Hartmann, Ulrich Wachter, Oscar McCook, Josef Vogt, Sandra Kress, Michael Gröger, Marina Fink, Angelika Scheuerle, Peter Möller, Enrico Calzia, Ute Burret, Peter Radermacher, Jan P. Tuckermann, Sabine Vettorazzi
Published 2020-01-01

13C-Metabolic flux analysis detected a hyperoxemia-induced reduction of tricarboxylic acid cycle metabolism in granulocytes during two models of porcine acute subdural hematoma and...

by Eva-Maria Wolfschmitt, Josef Albert Vogt, Melanie Hogg, Ulrich Wachter, Nicole Stadler, Thomas Kapapa, Thomas Datzmann, David Alexander Christian Messerer, David Alexander Christian Messerer, Andrea Hoffmann, Michael Gröger, Franziska Münz, Franziska Münz, René Mathieu, Simon Mayer, Tamara Merz, Tamara Merz, Pierre Asfar, Enrico Calzia, Peter Radermacher, Fabian Zink
Published 2024-01-01

The effect of sodium thiosulfate on immune cell metabolism during porcine hemorrhage and resuscitation

by Eva-Maria Wolfschmitt, Melanie Hogg, Josef Albert Vogt, Fabian Zink, Ulrich Wachter, Felix Hezel, Xiaomin Zhang, Andrea Hoffmann, Michael Gröger, Clair Hartmann, Holger Gässler, Thomas Datzmann, Thomas Datzmann, Tamara Merz, Andreas Hellmann, Christine Kranz, Enrico Calzia, Peter Radermacher, David Alexander Christian Messerer, David Alexander Christian Messerer, David Alexander Christian Messerer
Published 2023-02-01

Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock

by Sandra A. Appiah, Christine L. Foxx, Dominik Langgartner, Annette Palmer, Cristian A. Zambrano, Sonja Braumüller, Evan J. Schaefer, Ulrich Wachter, Brooke L. Elam, Peter Radermacher, Christopher E. Stamper, Jared D. Heinze, Stephanie N. Salazar, Amalia K. Luthens, Andrea L. Arnold, Stefan O. Reber, Markus Huber-Lang, Christopher A. Lowry, Rebecca Halbgebauer
Published 2021-03-01

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

by Rebecca Halbgebauer, Ebru Karasu, Christian K. Braun, Christian K. Braun, Annette Palmer, Sonja Braumüller, Anke Schultze, Fabian Schäfer, Sarah Bückle, Alica Eigner, Ulrich Wachter, Peter Radermacher, Ranillo R. G. Resuello, Joel V. Tuplano, Kristina Nilsson Ekdahl, Kristina Nilsson Ekdahl, Bo Nilsson, Milena Armacki, Alexander Kleger, Thomas Seufferlein, Miriam Kalbitz, Florian Gebhard, John D. Lambris, Martijn van Griensven, Markus Huber-Lang
Published 2020-08-01