Clinical utility of target amplicon sequencing test for rapid diagnosis of drug-resistant Mycobacterium tuberculosis from respiratory specimens

by Kenneth Siu-Sing Leung, Kingsley King-Gee Tam, Timothy Ting-Leung Ng, Hiu-Yin Lao, Raymond Chiu-Man Shek, Oliver Chiu Kit Ma, Shi-Hui Yu, Jing-Xian Chen, Qi Han, Gilman Kit-Hang Siu, Wing-Cheong Yam
Published 2022-09-01

Identification of microbial community in the urban environment: The concordance between conventional culture and nanopore 16S rRNA sequencing

by Annie Wing-Tung Lee, Chloe Toi-Mei Chan, Lily Lok-Yee Wong, Cheuk-Yi Yip, Wing-Tung Lui, Kai-Chun Cheng, Jake Siu-Lun Leung, Lam-Kwong Lee, Ivan Tak-Fai Wong, Timothy Ting-Leung Ng, Hiu-Yin Lao, Gilman Kit-Hang Siu
Published 2023-04-01

Screening Repurposed Antiviral Small Molecules as Antimycobacterial Compounds by a Lux-Based phoP Promoter-Reporter Platform

by Li Zhu, Annie Wing-Tung Lee, Kelvin Ka-Lok Wu, Peng Gao, Kingsley King-Gee Tam, Rahim Rajwani, Galata Chala Chaburte, Timothy Ting-Leung Ng, Chloe Toi-Mei Chan, Hiu Yin Lao, Wing Cheong Yam, Richard Yi-Tsun Kao, Gilman Kit Hang Siu
Published 2022-03-01

Genetic mechanisms of co-emergence of INH-resistant Mycobacterium tuberculosis strains during the standard course of antituberculosis therapy

by Ketema Tafess, Timothy Ting-Leung Ng, Kingsley King-Gee Tam, Kenneth Siu-Sing Leung, Jake Siu-Lun Leung, Lam-Kwong Lee, Hiu Yin Lao, Chloe Toi-Mei Chan, Wing-Cheong Yam, Samson Sai Yin Wong, Terrence Chi-Kwong Lau, Gilman Kit-Hang Siu
Published 2024-04-01

Evaluation of Mycobacterium tuberculosis enrichment in metagenomic samples using ONT adaptive sequencing and amplicon sequencing for identification and variant calling

by Junhao Su, Wui Wang Lui, YanLam Lee, Zhenxian Zheng, Gilman Kit-Hang Siu, Timothy Ting-Leung Ng, Tong Zhang, Tommy Tsan-Yuk Lam, Hiu-Yin Lao, Wing-Cheong Yam, Kingsley King-Gee Tam, Kenneth Siu-Sing Leung, Tak-Wah Lam, Amy Wing-Sze Leung, Ruibang Luo
Published 2023-03-01

A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis

by Rahim Rajwani, Chala Galata, Annie Wing Tung Lee, Pui-Kin So, Kenneth Siu Sing Leung, Kingsley King Gee Tam, Sheeba Shehzad, Timothy Ting Leung Ng, Li Zhu, Hiu Yin Lao, Chloe Toi-Mei Chan, Jake Siu-Lun Leung, Lam-Kwong Lee, Kin Chung Wong, Wing Cheong Yam, Gilman Kit-Hang Siu
Published 2022-12-01

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

by Bobo Wing-Yee Mok, Honglian Liu, Shaofeng Deng, Jiayan Liu, Anna Jinxia Zhang, Siu-Ying Lau, Siwen Liu, Rachel Chun-Yee Tam, Conor J. Cremin, Timothy Ting-Leung Ng, Jake Siu-Lun Leung, Lam-Kwong Lee, Pui Wang, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Hung Chan, Kwok-Yung Yuen, Gilman Kit-Hang Siu, Honglin Chen
Published 2021-09-01

The clinical utility of Nanopore 16S rRNA gene sequencing for direct bacterial identification in normally sterile body fluids

by Hiu-Yin Lao, Lily Lok-Yee Wong, Yan Hui, Timothy Ting-Leung Ng, Chloe Toi-Mei Chan, Hazel Wing-Hei Lo, Miranda Chong-Yee Yau, Eddie Chi-Man Leung, River Chun-Wai Wong, Alex Yat-Man Ho, Kam-Tong Yip, Jimmy Yiu-Wing Lam, Viola Chi-Ying Chow, Kristine Shik Luk, Tak-Lun Que, Franklin Wang Ngai Chow, Gilman Kit-Hang Siu
Published 2024-01-01

Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?

by Gilman Kit-Hang Siu, Lam-Kwong Lee, Kenneth Siu-Sing Leung, Jake Siu-Lun Leung, Timothy Ting-Leung Ng, Chloe Toi-Mei Chan, Kingsley King-Gee Tam, Hiu-Yin Lao, Alan Ka-Lun Wu, Miranda Chong-Yee Yau, Yvette Wai-Man Lai, Kitty Sau-Chun Fung, Sandy Ka-Yee Chau, Barry Kin-Chung Wong, Wing-Kin To, Kristine Luk, Alex Yat-Man Ho, Tak-Lun Que, Kam-Tong Yip, Wing Cheong Yam, David Ho-Keung Shum, Shea Ping Yip
Published 2020-01-01

Probable airborne transmission of Burkholderia pseudomallei causing an urban outbreak of melioidosis during typhoon season in Hong Kong, China

by Wing-Gi Wu, Marcus Ho-Hin Shum, Ivan Tak-Fai Wong, Kelvin Keru Lu, Lam-Kwong Lee, Jake Siu-Lun Leung, Hiu-Yin Lao, Annie Wing-Tung Lee, Pak-Ting Hau, Chloe Toi-Mei Chan, Harmen Fung-Tin Wong, Sharon Ka-Yee Fung, Sally Choi-Ying Wong, Iain Chi-Fung Ng, Timothy Ting-Leung Ng, Ning Chow, Alex Yat-Man Ho, Mei Fan Hung, Franklin Wang-Ngai Chow, Maureen Mo-Lin Wong, Wing-Kin To, Tommy Tsan-Yuk Lam, Kristine Shik Luk, Gilman Kit-Hang Siu
Published 2023-12-01

Territorywide Study of Early Coronavirus Disease Outbreak, Hong Kong, China

by Kenneth Siu-Sing Leung, Timothy Ting-Leung Ng, Alan Ka-Lun Wu, Miranda Chong-Yee Yau, Hiu-Yin Lao, Ming-Pan Choi, Kingsley King-Gee Tam, Lam-Kwong Lee, Barry Kin-Chung Wong, Alex Yat Man Ho, Kam-Tong Yip, Kwok-Cheung Lung, Raymond Wai-To Liu, Eugene Yuk-Keung Tso, Wai-Shing Leung, Man-Chun Chan, Yuk-Yung Ng, Kit-Man Sin, Kitty Sau-Chun Fung, Sandy Ka-Yee Chau, Wing-Kin To, Tak-Lun Que, David Ho-Keung Shum, Shea Ping Yip, Wing Cheong Yam, Gilman Kit-Hang Siu
Published 2021-01-01