Personalised analytics for rare disease diagnostics

by Denise Anderson, Gareth Baynam, Jenefer M. Blackwell, Timo Lassmann
Published 2019-11-01

Off-Target Effect of Endogenous siRNA Derived from RMRP in Human Cells

by Yoshiko Maida, Satoru Kyo, Timo Lassmann, Yoshihide Hayashizaki, Kenkichi Masutomi
Published 2013-04-01

CRISPR-Cas9-generated PTCHD1 2489T>G stem cells recapitulate patient phenotype when undergoing neural induction

by Kathryn O. Farley, Catherine A. Forbes, Nicole C. Shaw, Emma Kuzminski, Michelle Ward, Gareth Baynam, Timo Lassmann, Vanessa S. Fear
Published 2024-01-01

CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency

by Vanessa S. Fear, Catherine A. Forbes, Denise Anderson, Sebastian Rauschert, Genevieve Syn, Nicole Shaw, Sarra Jamieson, Michelle Ward, Gareth Baynam, Timo Lassmann
Published 2022-02-01

Ceruloplasmin is a novel adipokine which is overexpressed in adipose tissue of obese subjects and in obesity-associated cancer cells.

by Erik Arner, Alistair R R Forrest, Anna Ehrlund, Niklas Mejhert, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Jurga Laurencikiene, Mikael Rydén, Peter Arner, FANTOM Consortium
Published 2014-01-01

Telomerase Reverse Transcriptase Regulates microRNAs

by Timo Lassmann, Yoshiko Maida, Yasuhiro Tomaru, Mami Yasukawa, Yoshinari Ando, Miki Kojima, Vivi Kasim, Christophe Simon, Carsten O. Daub, Piero Carninci, Yoshihide Hayashizaki, Kenkichi Masutomi
Published 2015-01-01

Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli

by Annalaura Vacca, Masayoshi Itoh, Hideya Kawaji, Erik Arner, Timo Lassmann, Carsten O. Daub, Piero Carninci, Alistair R. R. Forrest, Yoshihide Hayashizaki, Stuart Aitken, Colin A. Semple
Published 2018-08-01

Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows

by Elena Denisenko, Belinda B. Guo, Matthew Jones, Rui Hou, Leanne de Kock, Timo Lassmann, Daniel Poppe, Olivier Clément, Rebecca K. Simmons, Ryan Lister, Alistair R. R. Forrest
Published 2020-06-01

Automated workflow for preparation of cDNA for cap analysis of gene expression on a single molecule sequencer.

by Masayoshi Itoh, Miki Kojima, Sayaka Nagao-Sato, Eri Saijo, Timo Lassmann, Mutsumi Kanamori-Katayama, Ai Kaiho, Marina Lizio, Hideya Kawaji, Piero Carninci, Alistair R R Forrest, Yoshihide Hayashizaki
Published 2012-01-01

Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage.

by Daniel Carbajo, Shigeyuki Magi, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Erik Arner, Alistair R R Forrest, Piero Carninci, Yoshihide Hayashizaki, Carsten O Daub, FANTOM consortium, Mariko Okada-Hatakeyama, Jessica C Mar
Published 2015-01-01

Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

by Vanessa S. Fear, Catherine A. Forbes, Nicole C. Shaw, Kathryn O. Farley, Jessica L. Mantegna, Jasmin P. Htun, Genevieve Syn, Helena Viola, Henrietta Cserne Szappanos, Livia Hool, Michelle Ward, Gareth Baynam, Timo Lassmann
Published 2023-12-01

Correction to: Relatively frequent switching of transcription start sites during cerebellar development

by Peter Zhang, Emmanuel Dimont, Thomas Ha, Douglas J. Swanson, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Carsten O. Daub, Erik Arner, the FANTOM Consortium, Piero Carninci, Yoshihide Hayashizaki, Alistair R. R. Forrest, Winston Hide, Dan Goldowitz
Published 2018-01-01

Systematic analysis of transcription start sites in avian development.

by Marina Lizio, Ruslan Deviatiiarov, Hiroki Nagai, Laura Galan, Erik Arner, Masayoshi Itoh, Timo Lassmann, Takeya Kasukawa, Akira Hasegawa, Marian A Ros, Yoshihide Hayashizaki, Piero Carninci, Alistair R R Forrest, Hideya Kawaji, Oleg Gusev, Guojun Sheng
Published 2017-09-01

Searching for a technology-driven acute rheumatic fever test: the START study protocol

by David Broadhurst, Bo Remenyi, Timothy C Barnett, Jonathan R Carapetis, Jennifer Yan, Anna P Ralph, Glenn Pearson, Mark Mayo, Rachel Webb, Nicole J Moreland, Reuben McGregor, Anthony Bosco, Timo Lassmann, Rym Benothman, Julie Bennett, Nigel Wilson
Published 2021-09-01

Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response.

by Stuart Aitken, Shigeyuki Magi, Ahmad M N Alhendi, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Carsten O Daub, Erik Arner, Piero Carninci, Alistair R R Forrest, Yoshihide Hayashizaki, FANTOM Consortium, Levon M Khachigian, Mariko Okada-Hatakeyama, Colin A Semple
Published 2015-04-01

Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy

by Wee Loong Chin, Rachael M. Zemek, Caitlin M. Tilsed, Alistair R. R. Forrest, Vanessa S. Fear, Catherine Forbes, Louis Boon, Anthony Bosco, Belinda B. Guo, Michael J. Millward, Anna K. Nowak, Richard A. Lake, W. Joost Lesterhuis, Timo Lassmann
Published 2024-05-01

Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

by Joel Kidman, Joel Kidman, Nicola Principe, Nicola Principe, Mark Watson, Timo Lassmann, Robert A. Holt, Anna K. Nowak, Anna K. Nowak, Willem Joost Lesterhuis, Willem Joost Lesterhuis, Willem Joost Lesterhuis, Richard A. Lake, Richard A. Lake, Jonathan Chee, Jonathan Chee
Published 2020-10-01

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages

by Sugata Roy, Sebastian Schmeier, Bogumil Kaczkowski, Erik Arner, Tanvir Alam, Mumin Ozturk, Ousman Tamgue, Suraj P. Parihar, Hideya Kawaji, Masayoshi Itoh, Timo Lassmann, Piero Carninci, Yoshihide Hayashizaki, Alistair R. R. Forrest, Reto Guler, Vladimir B. Bajic, Frank Brombacher, Harukazu Suzuki
Published 2018-04-01

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

by J Kenneth Baillie, Erik Arner, Carsten Daub, Michiel De Hoon, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Piero Carninci, Alistair R R Forrest, Yoshihide Hayashizaki, FANTOM Consortium, Geoffrey J Faulkner, Christine A Wells, Michael Rehli, Paul Pavli, Kim M Summers, David A Hume
Published 2017-03-01

Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice

by Rachael M. Zemek, Wee Loong Chin, Vanessa S. Fear, Ben Wylie, Thomas H. Casey, Cath Forbes, Caitlin M. Tilsed, Louis Boon, Belinda B. Guo, Anthony Bosco, Alistair R. R. Forrest, Michael J. Millward, Anna K. Nowak, Richard A. Lake, Timo Lassmann, W. Joost Lesterhuis
Published 2022-08-01