Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis

by Tiago L. Duarte, Carolina Caldas, Ana G. Santos, Sandro Silva-Gomes, Andreia Santos-Gonçalves, Maria João Martins, Graça Porto, José Manuel Lopes
Published 2017-04-01

Ferritin Increase in Hemochromatosis Subjects After Discontinuing Their Regular Maintenance Treatment: A Longitudinal Analysis Performed During the COVID-19 Imposed Hospital Lockdo...

by Maria P. Coutinho, Maria José Teles, Graça Melo, Marta Lopes, Delfim Duarte, Tiago L. Duarte, Júlia Reis, Ana Cláudia Martins, José Carlos Oliveira, Graça Porto
Published 2022-09-01

Cellular iron governs the host response to malaria.

by Sarah K Wideman, Joe N Frost, Felix C Richter, Caitlin Naylor, José M Lopes, Nicole Viveiros, Megan R Teh, Alexandra E Preston, Natasha White, Shamsideen Yusuf, Simon J Draper, Andrew E Armitage, Tiago L Duarte, Hal Drakesmith
Published 2023-10-01

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

by Sant-Rayn Pasricha, Pei Jin Lim, Tiago L. Duarte, Carla Casu, Dorenda Oosterhuis, Katarzyna Mleczko-Sanecka, Maria Suciu, Ana Rita Da Silva, Kinda Al-Hourani, João Arezes, Kirsty McHugh, Sarah Gooding, Joe N. Frost, Katherine Wray, Ana Santos, Graça Porto, Emmanouela Repapi, Nicki Gray, Simon J. Draper, Neil Ashley, Elizabeth Soilleux, Peter Olinga, Martina U. Muckenthaler, Jim R. Hughes, Stefano Rivella, Thomas A. Milne, Andrew E. Armitage, Hal Drakesmith
Published 2017-09-01