Real-Time Million-Synapse Simulation of Rat Barrel Cortex

by Thomas eSharp, Thomas eSharp, Rasmus S Petersen, Steve B Furber
Published 2014-05-01

Stem Cell Therapy and Breast Cancer Treatment: review of stem cell research and potential therapeutic impact against cardiotoxicities due to breast cancer treatment

by Thomas E. Sharp, Jon C. George, Jon C. George
Published 2014-11-01

Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure

by Chelsea L. Organ, Zhen Li, Thomas E. Sharp, David J. Polhemus, Nilaksh Gupta, Traci T. Goodchild, W. H. Wilson Tang, Stanley L. Hazen, David J. Lefer
Published 2020-05-01

Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

by Huijing Xia, Zhen Li, Thomas E. Sharp, David J. Polhemus, Jean Carnal, Karl H. Moles, Ya‐Xiong Tao, John Elrod, Josef Pfeilschifter, Karl‐Friedrich Beck, David J. Lefer
Published 2020-10-01

Common Heart Failure With Preserved Ejection Fraction Animal Models Yield Disparate Myofibril Mechanics

by Axel J. Fenwick, Vivek P. Jani, D. Brian Foster, Thomas E. Sharp, Traci T. Goodchild, Kyle LaPenna, Jake E. Doiron, David J. Lefer, Joseph A. Hill, David A. Kass, Anthony Cammarato
Published 2024-01-01

Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a “2‐Hit” Murine Model

by Kyle B. LaPenna, Zhen Li, Jake E. Doiron, Thomas E. Sharp, Huijing Xia, Karl Moles, Kashyap Koul, John S. Wang, David J. Polhemus, Traci T. Goodchild, Ravi B. Patel, Sanjiv J. Shah, David J. Lefer
Published 2023-02-01

Early Renal Denervation Attenuates Cardiac Dysfunction in Heart Failure With Preserved Ejection Fraction

by Jake E. Doiron, Zhen Li, Xiaoman Yu, Kyle B. LaPenna, Heather Quiriarte, Timothy D. Allerton, Kashyap Koul, Andrew Malek, Sanjiv J. Shah, Thomas E. Sharp, Traci T. Goodchild, Daniel R. Kapusta, David J. Lefer
Published 2024-02-01

Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure

by Zhen Li, BS, Chelsea L. Organ, PhD, Jianming Kang, PhD, David J. Polhemus, PhD, Rishi K. Trivedi, PhD, Thomas E. Sharp, III, PhD, Jack S. Jenkins, Ya-xiong Tao, PhD, Ming Xian, PhD, David J. Lefer, PhD
Published 2018-12-01

Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction

by Thomas E. Sharp, III, BA, Hajime Kubo, PhD, Remus M. Berretta, BS, Timothy Starosta, BS, Markus Wallner, MD, PhD, Giana J. Schena, BS, Alexander R. Hobby, BS, Daohai Yu, PhD, Danielle M. Trappanese, PhD, Jon C. George, MD, Jeffery D. Molkentin, PhD, Steven R. Houser, PhD
Published 2017-12-01