195 Overcoming the dose-response prediction limitation from bench to clinic for T-cell engagers: using quantitative systems pharmacology (QSP) modelling in the development of CDR40...

by Fei Hua, Swethajit Biswas, Melissa Vrohlings, Stephanie Jungmichel, Ivana Tosevski, Nadia Sanchez, Leonardo Borras, Drew Marquis, Scott Gruver
Published 2023-11-01

Analysis of Cardiac Amyloidosis Progression Using Model-Based Markers

by Wenguang Li, Alan Lazarus, Hao Gao, Ana Martinez-Naharro, Marianna Fontana, Philip Hawkins, Swethajit Biswas, Robert Janiczek, Jennifer Cox, Colin Berry, Dirk Husmeier, Xiaoyu Luo
Published 2020-04-01

1397 CDR404, an antibody-based bispecific & bivalent T-cell engager targeted against MAGE-A4, for Squamous Non-Small Cell Lung Cancer (SQ-NSCLC)

by Elizabeth Ross, Swethajit Biswas, Gilberto Lopes, Melissa Vrohlings, Stephanie Jungmichel, Ivana Tosevski, Alessio Vantellini, Philip Knobel, Nadia Sanchez, Marian Van Kerckhoven, Giorgia Giacomazzi, Maria Liivrand, Reija Hieta, Nicholas Dupuis, Dieter Rondas, Pamela Swatkowski, Daniel Lenherr-Frey, Leonardo Borras
Published 2023-11-01

Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an...

by Ashutosh Wechalekar, Gunnar Antoni, Wasfi Al Azzam, Mats Bergström, Swethajit Biswas, Chao Chen, Joseph Cheriyan, Matthew Cleveland, Louise Cookson, Paul Galette, Robert L. Janiczek, Raymond Y. Kwong, Mary Ann Lukas, Helen Millns, Duncan Richards, Ian Schneider, Scott D. Solomon, Jens Sörensen, James Storey, Douglas Thompson, Guus van Dongen, Danielle J. Vugts, Anders Wall, Gerhard Wikström, Rodney H. Falk
Published 2022-02-01