Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor

by Steven A. Kliewer, Timothy M. Willson
Published 2002-03-01

Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor.

by Bethany T Nelson, Xunshan Ding, Jamie Boney-Montoya, Robert D Gerard, Steven A Kliewer, Matthew T Andrews
Published 2013-01-01

FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption

by Diana Jung, Takeshi Inagaki, Robert D. Gerard, Paul A. Dawson, Steven A. Kliewer, David J. Mangelsdorf, Antonio Moschetta
Published 2007-12-01

The Schistosoma mansoni nuclear receptor FTZ-F1 maintains esophageal gland function via transcriptional regulation of meg-8.3.

by Aracely A Romero, Sarah A Cobb, Julie N R Collins, Steven A Kliewer, David J Mangelsdorf, James J Collins
Published 2021-12-01

Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine

by Insook Kim, Sung-Hoon Ahn, Takeshi Inagaki, Mihwa Choi, Shinji Ito, Grace L. Guo, Steven A. Kliewer, Frank J. Gonzalez
Published 2007-12-01

Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation

by Katherine Omueti Ayoade, Faith R. Carranza, Woong Hee Cho, Zhu Wang, Steven A. Kliewer, David J. Mangelsdorf, Jonathan D. C. Stoltzfus
Published 2020-04-01

The nuclear receptor DAF-12 regulates nutrient metabolism and reproductive growth in nematodes.

by Zhu Wang, Jonathan Stoltzfus, Young-Jai You, Najju Ranjit, Hao Tang, Yang Xie, James B Lok, David J Mangelsdorf, Steven A Kliewer
Published 2015-03-01

Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid.

by Mennatallah M Y Albarqi, Jonathan D Stoltzfus, Adeiye A Pilgrim, Thomas J Nolan, Zhu Wang, Steven A Kliewer, David J Mangelsdorf, James B Lok
Published 2016-01-01

Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis

by Zhu Wang, Mi Cheong Cheong, Jet Tsien, Heping Deng, Tian Qin, Jonathan DC Stoltzfus, Tegegn G Jaleta, Xinshe Li, James B Lok, Steven A Kliewer, David J Mangelsdorf
Published 2021-12-01

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

by Yuan Zhang, Yang Xie, Eric D Berglund, Katie Colbert Coate, Tian Teng He, Takeshi Katafuchi, Guanghua Xiao, Matthew J Potthoff, Wei Wei, Yihong Wan, Ruth T Yu, Ronald M Evans, Steven A Kliewer, David J Mangelsdorf
Published 2012-10-01

Effects of fenofibrate on lipid parameters in obese rhesus monkeys

by Deborah A. Winegar, Peter J. Brown, William O. Wilkison, Michael C. Lewis, Ronda J. Ott, W.Q. Tong, H. Roger Brown, Jurgen M. Lehmann, Steven A. Kliewer, Kelli D. Plunket, James M. Way, Noni L. Bodkin, Barbara C. Hansen
Published 2001-10-01

FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes

by Mohammad Abu-Odeh, Yuan Zhang, Shannon M. Reilly, Nima Ebadat, Omer Keinan, Joseph M. Valentine, Maziar Hafezi-Bakhtiari, Hadeel Ashayer, Lana Mamoun, Xin Zhou, Jin Zhang, Ruth T. Yu, Yang Dai, Christopher Liddle, Michael Downes, Ronald M. Evans, Steven A. Kliewer, David J. Mangelsdorf, Alan R. Saltiel
Published 2021-06-01

Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers

by Kenneth E. Huffman, Kenneth E. Huffman, Long Shan Li, Long Shan Li, Ryan Carstens, Ryan Carstens, Hyunsil Park, Hyunsil Park, Luc Girard, Luc Girard, Kimberley Avila, Kimberley Avila, Shuguang Wei, Rahul Kollipara, Brenda Timmons, Brenda Timmons, Jessica Sudderth, Nawal Bendris, Jiyeon Kim, Jiyeon Kim, Pamela Villalobos, Junya Fujimoto, Sandra Schmid, Ralph J. Deberardinis, Ignacio Wistuba, John Heymach, Ralf Kittler, Ralf Kittler, Ralf Kittler, Esra A. Akbay, Bruce Posner, Yuzhuo Wang, Stephen Lam, Steven A. Kliewer, Steven A. Kliewer, David J. Mangelsdorf, David J. Mangelsdorf, John D. Minna, John D. Minna, John D. Minna, John D. Minna
Published 2023-03-01