Pulmonary Arterial Hypertension: Iron Matters

by Latha Ramakrishnan, Sofia L. Pedersen, Quezia K. Toe, Gregory J. Quinlan, Stephen J. Wort
Published 2018-05-01

miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.

by Martin Connolly, Benjamin E Garfield, Alexi Crosby, Nick W Morrell, Stephen J Wort, Paul R Kemp
Published 2020-01-01

The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.

by Louise S Harrington, Laura Moreno, Anna Reed, Stephen J Wort, Béatrice Desvergne, Christopher Garland, Lan Zhao, Jane A Mitchell
Published 2010-03-01

Outcome of cardiac surgery in patients with congenital heart disease in England between 1997 and 2015.

by Aleksander Kempny, Konstantinos Dimopoulos, Anselm Uebing, Gerhard-Paul Diller, Ulrich Rosendahl, George Belitsis, Michael A Gatzoulis, Stephen J Wort
Published 2017-01-01

Pulmonary hypertension in the setting of interstitial lung disease: Approach to management and treatment. A consensus statement from the Pulmonary Vascular Research Institute's Inn...

by Oksana A. Shlobin, Eric Shen, Stephen J. Wort, Lucilla Piccari, John A. Scandurra, Paul M. Hassoun, Sylvia M. Nikkho, Steven D. Nathan
Published 2024-01-01

Exercise ventilatory reserve predicts survival in adult congenital heart disease associated pulmonary arterial hypertension with Eisenmenger physiology

by Chinthaka B. Samaranayake, Ruth McNiven, Aleksander Kempny, Carl Harries, Laura C. Price, Michael Gatzoulis, Konstantinos Dimopoulos, Stephen J. Wort, Colm McCabe
Published 2022-03-01

BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.

by John E S Park, Dongmin Shao, Paul D Upton, Patricia Desouza, Ian M Adcock, Rachel J Davies, Nicholas W Morrell, Mark J D Griffiths, Stephen J Wort
Published 2012-01-01

Correction: BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production.

by John E. S. Park, Dongmin Shao, Paul D. Upton, Patricia deSouza, Ian M. Adcock, Rachel J. Davies, Nicholas W. Morrell, Mark J. D. Griffiths, Stephen J. Wort
Published 2013-01-01

Rescue therapy with thrombolysis in patients with severe COVID-19-associated acute respiratory distress syndrome

by Laura C. Price, Benjamin Garfield, Caroline Bleakley, Archie G.M. Keeling, Charles Mcfadyen, Colm McCabe, Carole A. Ridge, Stephen J. Wort, Susanna Price, Deepa J. Arachchillage
Published 2020-12-01

miR‐424‐5p reduces ribosomal RNA and protein synthesis in muscle wasting

by Martin Connolly, Richard Paul, Roser Farre‐Garros, Samantha A. Natanek, Susannah Bloch, Jen Lee, Jose P. Lorenzo, Harnish Patel, Cyrus Cooper, Avan A. Sayer, Stephen J. Wort, Mark Griffiths, Michael I. Polkey, Paul R. Kemp
Published 2018-04-01

Sendaway capillary NT-proBNP in pulmonary hypertension

by Eleanor Morris, Stephen J Wort, Martin K Johnson, James L Lordan, Daniel S Knight, Chloe Roddis, Charlotte Durrington, Harrison D Stubbs, John Cannon, Emily Knightbridge, Wendy Gin-Sing, Fiona Massey, Ruta Virsinskaite, Eleanor Sear, Joy Apple-Pinguel
Published 2024-03-01

Positioning imatinib for pulmonary arterial hypertension: A phase I/II design comprising dose finding and single-arm efficacy

by Martin R. Wilkins, Mikel A. Mckie, Martin Law, Andreas A. Roussakis, Lars Harbaum, Colin Church, J Gerry Coghlan, Robin Condliffe, Luke S Howard, David G Kiely, Jim Lordan, Alexander Rothman, Jay Suntharalingam, Mark Toshner, Stephen J Wort, Sofía S. Villar
Published 2021-10-01

Clinical significance of pulmonary hypertension in interstitial lung disease: A consensus statement from the Pulmonary Vascular Research Institute's innovative drug development ini...

by Sylvia M. Nikkho, Manuel J. Richter, Eric Shen, Steven H. Abman, Katerina Antoniou, Jonathan Chung, Peter Fernandes, Paul Hassoun, Howard M. Lazarus, Horst Olschewski, Lucilla Piccari, Mitchell Psotka, Rajan Saggar, Oksana A. Shlobin, Norman Stockbridge, Patrizio Vitulo, Carmine Dario Vizza, Stephen J. Wort, Steven D. Nathan
Published 2022-07-01

Pulmonary hemodynamics and transplant‐free survival in sarcoidosis‐associated pulmonary hypertension: Results from an international registry

by Shameek K. Gayen, Robert P. Baughman, Steven D. Nathan, Athol U. Wells, Vasilis Kouranos, Esam H. Alhamad, Daniel A. Culver, Joseph Barney, Eva M. Carmoma, Francis C. Cordova, Marloes Huitema, Mary Beth Scholand, Marlies Wijsenbeek, Sivagini Ganesh, Surinder S. Birring, Laura C. Price, Stephen J. Wort, Oksana A. Shlobin, Rohit Gupta
Published 2023-10-01

Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension

by Anna Ulrich, Yukyee Wu, Harmen Draisma, John Wharton, Emilia M. Swietlik, Inês Cebola, Eleni Vasilaki, Zhanna Balkhiyarova, Marjo-Riitta Jarvelin, Juha Auvinen, Karl-Heinz Herzig, J. Gerry Coghlan, James Lordan, Colin Church, Luke S. Howard, Joanna Pepke-Zaba, Mark Toshner, Stephen J. Wort, David G. Kiely, Robin Condliffe, Allan Lawrie, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes
Published 2024-01-01

Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI)

by David G. Kiely, David L. Levin, Paul M. Hassoun, Dunbar Ivy, Pei-Ni Jone, Jumaa Bwika, Steven M. Kawut, Jim Lordan, Angela Lungu, Jeremy A. Mazurek, Shahin Moledina, Horst Olschewski, Andrew J. Peacock, G.D. Puri, Farbod N. Rahaghi, Michal Schafer, Mark Schiebler, Nicholas Screaton, Merryn Tawhai, Edwin J.R. van Beek, Anton Vonk-Noordegraaf, Rebecca Vandepool, Stephen J. Wort, Lan Zhao, Jim M. Wild, Jens Vogel-Claussen, Andrew J. Swift
Published 2019-09-01

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

by Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M. Salmon, Mark Southwood, Rajiv D. Machado, Jennifer M. Martin, Carmen M. Treacy, Katherine Yates, Louise C. Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala Aldred, Harm J. Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A. Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J. Simon R. Gibbs, Barbara Girerd, Arjan C. Houweling, Luke Howard, Marc Humbert, David G. Kiely, Gabor Kovacs, Robert V. MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J. Peacock, Joanna Pepke-Zaba, Inga Prokopenko, Christopher J. Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan F. Stein, Jay Suntharalingam, Emilia M. Swietlik, Mark R. Toshner, David A. van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J. Wort, Willem H. Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D. Upton, Martin R. Wilkins, Richard C. Trembath, Nicholas W. Morrell
Published 2018-04-01