MicroRNAs in Neuroinflammation: Implications in Disease Pathogenesis, Biomarker Discovery and Therapeutic Applications

by Jessy A. Slota, Stephanie A. Booth
Published 2019-04-01

Neurons and Astrocytes Elicit Brain Region Specific Transcriptional Responses to Prion Disease in the Murine CA1 and Thalamus

by Jessy A. Slota, Jessy A. Slota, Sarah J. Medina, Kathy L. Frost, Stephanie A. Booth, Stephanie A. Booth
Published 2022-05-01

Application of “omics” to Prion Biomarker Discovery

by Rhiannon L. C. H. Huzarewich, Christine G. Siemens, Stephanie A. Booth
Published 2010-01-01

Application of DNA Array Technology for Diagnostic Microbiology

by Stephanie A Booth, Michael A Drebot, Graham A Tipples, Lai King Ng
Published 2000-01-01

Differentiated cultures of an immortalized human neural progenitor cell line do not replicate prions despite PrPC overexpression

by Jessy A. Slota, Xinzhu Wang, Diana Lusansky, Sarah J. Medina, Stephanie A. Booth
Published 2023-12-01

Exposure Risk of Chronic Wasting Disease in Humans

by Satish K. Nemani, Jennifer L. Myskiw, Lise Lamoureux, Stephanie A. Booth, Valerie L. Sim
Published 2020-12-01

A miRNA signature of prion induced neurodegeneration.

by Reuben Saba, Chelsey D Goodman, Rhiannon L C H Huzarewich, Catherine Robertson, Stephanie A Booth
Published 2008-01-01

Dysregulation of neuroprotective astrocytes, a spectrum of microglial activation states, and altered hippocampal neurogenesis are revealed by single-cell RNA sequencing in prion di...

by Jessy A. Slota, Babu V. Sajesh, Kathy F. Frost, Sarah J. Medina, Stephanie A. Booth
Published 2022-11-01

MicroRNA-16 targets mRNA involved in neurite extension and branching in hippocampal neurons during presymptomatic prion disease

by Kristyn Burak, Lise Lamoureux, Amrit Boese, Anna Majer, Reuben Saba, Yulian Niu, Kathy Frost, Stephanie A. Booth
Published 2018-04-01

Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis.

by Anna Majer, Kyle A Caligiuri, Kamilla K Gale, Yulian Niu, Clark S Phillipson, Timothy F Booth, Stephanie A Booth
Published 2017-01-01

MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state.

by Reuben Saba, Shantel Gushue, Rhiannon L C H Huzarewich, Kathy Manguiat, Sarah Medina, Catherine Robertson, Stephanie A Booth
Published 2012-01-01

Correction: Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis.

by Anna Majer, Kyle A Caligiuri, Kamilla K Gale, Yulian Niu, Clark S Phillipson, Timothy F Booth, Stephanie A Booth
Published 2017-01-01

The cell type resolved mouse transcriptome in neuron-enriched brain tissues from the hippocampus and cerebellum during prion disease

by Anna Majer, Sarah J. Medina, Debra Sorensen, Matthew J. Martin, Kathy L. Frost, Clark Phillipson, Kathy Manguiat, Stephanie A. Booth
Published 2019-01-01

Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice.

by Anna Majer, Sarah J Medina, Yulian Niu, Bernard Abrenica, Kathy J Manguiat, Kathy L Frost, Clark S Philipson, Debra L Sorensen, Stephanie A Booth
Published 2012-01-01

SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus.

by Kulbhushan Sharma, Sara Åkerström, Anuj Kumar Sharma, Vincent T K Chow, Shumein Teow, Bernard Abrenica, Stephanie A Booth, Timothy F Booth, Ali Mirazimi, Sunil K Lal
Published 2011-01-01

Non-Productive Infection of Glial Cells with SARS-CoV-2 in Hamster Organotypic Cerebellar Slice Cultures

by Lise Lamoureux, Babu Sajesh, Jessy A. Slota, Sarah J. Medina, Matthew Mayor, Kathy L. Frost, Bryce Warner, Kathy Manguiat, Heidi Wood, Darwyn Kobasa, Stephanie A. Booth
Published 2022-06-01

Identification of circulating microRNA signatures as potential biomarkers in the serum of elk infected with chronic wasting disease

by Jessy A. Slota, Sarah J. Medina, Megan Klassen, Damian Gorski, Christine M. Mesa, Catherine Robertson, Gordon Mitchell, Michael B. Coulthart, Sandra Pritzkow, Claudio Soto, Stephanie A. Booth
Published 2019-12-01

A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice

by Laura P. van Lieshout, Jakob M. Domm, Tara N. Rindler, Kathy L. Frost, Debra L. Sorensen, Sarah J. Medina, Stephanie A. Booth, James P. Bridges, Sarah K. Wootton
Published 2018-06-01

Downregulation of circulating miR 802‐5p and miR 194‐5p and upregulation of brain MEF2C along breast cancer brain metastasization

by Marta Sereno, János Haskó, Kinga Molnár, Sarah J. Medina, Zita Reisz, Rui Malhó, Mafalda Videira, László Tiszlavicz, Stephanie A. Booth, Imola Wilhelm, István A. Krizbai, Maria Alexandra Brito
Published 2020-03-01

Generation and Characterization of a SARS-CoV-2-Susceptible Mouse Model Using Adeno-Associated Virus (AAV6.2FF)-Mediated Respiratory Delivery of the Human ACE2 Gene

by Nikesh Tailor, Bryce M. Warner, Bryan D. Griffin, Kevin Tierney, Estella Moffat, Kathy Frost, Robert Vendramelli, Anders Leung, Marnie Willman, Sylvia P. Thomas, Yanlong Pei, Stephanie A. Booth, Carissa Embury-Hyatt, Sarah K. Wootton, Darwyn Kobasa
Published 2022-12-01