Fighting the Host Reaction to SARS-COv-2 in Critically Ill Patients: The Possible Contribution of Off-Label Drugs

by Stefania Scala, Roberto Pacelli
Published 2020-05-01

CXCR4 and CXCR7 Signaling Pathways: A Focus on the Cross-Talk Between Cancer Cells and Tumor Microenvironment

by Sara Santagata, Caterina Ieranò, Anna Maria Trotta, Anna Capiluongo, Federica Auletta, Giuseppe Guardascione, Stefania Scala
Published 2021-04-01

Prognostic Significance of CXCR4 in Colorectal Cancer: An Updated Meta-Analysis and Critical Appraisal

by Alessandro Ottaiano, Mariachiara Santorsola, Paola Del Prete, Francesco Perri, Stefania Scala, Michele Caraglia, Guglielmo Nasti
Published 2021-06-01

New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM

by Stefania Scala, Crescenzo D’Alterio, Samantha Milanesi, Alessandra Castagna, Roberta Carriero, Floriana Maria Farina, Massimo Locati, Elena Monica Borroni
Published 2020-04-01

Unexpected tumor reduction in metastatic colorectal cancer patients during SARS-Cov-2 infection

by Alessandro Ottaiano, Stefania Scala, Crescenzo D’Alterio, Annamaria Trotta, Annamaria Bello, Giuseppina Rea, Carmine Picone, Mariachiara Santorsola, Antonella Petrillo, Guglielmo Nasti
Published 2021-04-01

Tumour biomarkers: homeostasis as a novel prognostic indicator

by Michela Falco, Giuseppe Palma, Domenica Rea, Davide De Biase, Stefania Scala, Massimiliano D'Aiuto, Gaetano Facchini, Sisto Perdonà, Antonio Barbieri, Claudio Arra
Published 2016-01-01

Conformational Ensembles Explored Dynamically from Disordered Peptides Targeting Chemokine Receptor CXCR4

by Marian Vincenzi, Susan Costantini, Stefania Scala, Diego Tesauro, Antonella Accardo, Marilisa Leone, Giovanni Colonna, Jean Guillon, Luigi Portella, Anna Maria Trotta, Luisa Ronga, Filomena Rossi
Published 2015-05-01

IRF-8 Controls Melanoma Progression by Regulating the Cross Talk between Cancer and Immune Cells within the Tumor Microenvironment

by Fabrizio Mattei, Giovanna Schiavoni, Paola Sestili, Francesca Spadaro, Alessandra Fragale, Antonella Sistigu, Valeria Lucarini, Massimo Spada, Massimo Sanchez, Stefania Scala, Angela Battistini, Filippo Belardelli, Lucia Gabriele
Published 2012-12-01

A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors

by Sara Santagata, Luigi Portella, Maria Napolitano, Adelaide Greco, Crescenzo D’Alterio, Maria Vittoria Barone, Antonio Luciano, Matteo Gramanzini, Luigi Auletta, Claudio Arra, Antonella Zannetti, Stefania Scala
Published 2017-05-01

Effect of Octreotide Long-Acting Release on Tregs and MDSC Cells in Neuroendocrine Tumour Patients: A Pivotal Prospective Study

by Claudia von Arx, Giuseppina Rea, Maria Napolitano, Alessandro Ottaiano, Fabiana Tatangelo, Francesco Izzo, Antonella Petrillo, Ottavia Clemente, Antonella Di Sarno, Gerardo Botti, Stefania Scala, Salvatore Tafuto
Published 2020-08-01

Variability in Immunohistochemical Detection of Programmed Death Ligand 1 (PD-L1) in Cancer Tissue Types

by Giosuè Scognamiglio, Anna De Chiara, Maurizio Di Bonito, Fabiana Tatangelo, Nunzia Simona Losito, Annamaria Anniciello, Rossella De Cecio, Crescenzo D’Alterio, Stefania Scala, Monica Cantile, Gerardo Botti
Published 2016-05-01

CXCR4-CXCL12-CXCR7 and PD-1/PD-L1 in Pancreatic Cancer: CXCL12 Predicts Survival of Radically Resected Patients

by Crescenzo D’Alterio, Alessandro Giardino, Giosuè Scognamiglio, Giovanni Butturini, Luigi Portella, Giuseppe Guardascione, Isabella Frigerio, Marco Montella, Stefano Gobbo, Guido Martignoni, Vincenzo Napolitano, Ferdinando De Vita, Fabiana Tatangelo, Renato Franco, Stefania Scala
Published 2022-10-01

Tailoring the Structure of Cell Penetrating DNA and RNA Binding Nucleopeptides

by Stefano Tomassi, Caterina Ieranò, Alessandra Del Bene, Antonia D’Aniello, Maria Napolitano, Giuseppina Rea, Federica Auletta, Luigi Portella, Anna Capiluongo, Vincenzo Mazzarella, Rosita Russo, Angela Chambery, Stefania Scala, Salvatore Di Maro, Anna Messere
Published 2022-07-01

Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity

by Anna Maria Trotta, Sara Santagata, Serena Zanotta, Crescenzo D’Alterio, Maria Napolitano, Giuseppina Rea, Rosa Camerlingo, Fabio Esposito, Elvira Lamantia, Annamaria Anniciello, Giovanni Botti, Nicola Longo, Gerardo Botti, Sandro Pignata, Sisto Perdonà, Stefania Scala
Published 2018-12-01

PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells

by Federica Liotti, Narender Kumar, Nella Prevete, Maria Marotta, Daniela Sorriento, Caterina Ieranò, Andrea Ronchi, Federica Zito Marino, Sonia Moretti, Renato Colella, Efiso Puxeddu, Simona Paladino, Yoshihito Kano, Michael Ohh, Stefania Scala, Rosa Marina Melillo
Published 2021-01-01

Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases.

by Luigi Portella, Rosamaria Vitale, Stefania De Luca, Crescenzo D'Alterio, Caterina Ieranò, Maria Napolitano, Anna Riccio, Maria Neve Polimeno, Luca Monfregola, Antonio Barbieri, Antonio Luciano, Andrea Ciarmiello, Claudio Arra, Giuseppe Castello, Pietro Amodeo, Stefania Scala
Published 2013-01-01

CXCR4 Inhibition Counteracts Immunosuppressive Properties of Metastatic NSCLC Stem Cells

by Orazio Fortunato, Dimas Carolina Belisario, Mara Compagno, Francesca Giovinazzo, Cristiano Bracci, Cristiano Bracci, Ugo Pastorino, Alberto Horenstein, Alberto Horenstein, Fabio Malavasi, Fabio Malavasi, Riccardo Ferracini, Stefania Scala, Gabriella Sozzi, Luca Roz, Ilaria Roato, Giulia Bertolini
Published 2020-10-01

Study of Ras Mutations’ Prognostic Value in Metastatic Colorectal Cancer: STORIA Analysis

by Alessandro Ottaiano, Nicola Normanno, Sergio Facchini, Antonino Cassata, Anna Nappi, Carmela Romano, Lucrezia Silvestro, Alfonso De Stefano, Anna Maria Rachiglio, Cristin Roma, Monica R. Maiello, Stefania Scala, Paolo Delrio, Fabiana Tatangelo, Annabella Di Mauro, Gerardo Botti, Antonio Avallone, Guglielmo Nasti
Published 2020-07-01

Targeting CXCR4 potentiates anti-PD-1 efficacy modifying the tumor microenvironment and inhibiting neoplastic PD-1

by Crescenzo D’Alterio, Maria Buoncervello, Caterina Ieranò, Maria Napolitano, Luigi Portella, Giuseppina Rea, Antonio Barbieri, Antonio Luciano, Giosuè Scognamiglio, Fabiana Tatangelo, Anna Maria Anniciello, Mario Monaco, Ernesta Cavalcanti, Piera Maiolino, Giulia Romagnoli, Claudio Arra, Gerardo Botti, Lucia Gabriele, Stefania Scala
Published 2019-10-01

New CXCR4 Antagonist Peptide R (Pep R) Improves Standard Therapy in Colorectal Cancer

by Crescenzo D’Alterio, Antonella Zannetti, Anna Maria Trotta, Caterina Ieranò, Maria Napolitano, Giuseppina Rea, Adelaide Greco, Piera Maiolino, Sandra Albanese, Giosuè Scognamiglio, Fabiana Tatangelo, Salvatore Tafuto, Luigi Portella, Sara Santagata, Guglielmo Nasti, Alessandro Ottaiano, Roberto Pacelli, Paolo Delrio, Gerardo Botti, Stefania Scala
Published 2020-07-01