The activation thresholds and inactivation kinetics of poking-evoked PIEZO1 and PIEZO2 currents are sensitive to subtle variations in mechanical stimulation parameters

by Nadja Zeitzschel, Stefan G. Lechner
Published 2024-12-01

Intrinsically disordered intracellular domains control key features of the mechanically-gated ion channel PIEZO2

by Clement Verkest, Irina Schaefer, Timo A. Nees, Na Wang, Juri M. Jegelka, Francisco J. Taberner, Stefan G. Lechner
Published 2022-03-01

Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons

by Pratibha Narayanan, Meike Hütte, Galina Kudryasheva, Francisco J Taberner, Stefan G Lechner, Florian Rehfeldt, David Gomez-Varela, Manuela Schmidt
Published 2018-03-01

TTX-Resistant Sodium Channels Functionally Separate Silent From Polymodal C-nociceptors

by Robin Jonas, Vincenzo Prato, Stefan G. Lechner, Gerbrand Groen, Otilia Obreja, Fiona Werland, Roman Rukwied, Andreas Klusch, Marlen Petersen, Richard W. Carr, Martin Schmelz
Published 2020-02-01

Functional and Molecular Characterization of Mechanoinsensitive “Silent” Nociceptors

by Vincenzo Prato, Francisco J. Taberner, James R.F. Hockley, Gerard Callejo, Alice Arcourt, Bassim Tazir, Leonie Hammer, Paulina Schad, Paul A. Heppenstall, Ewan S. Smith, Stefan G. Lechner
Published 2017-12-01

A genetic basis for mechanosensory traits in humans.

by Henning Frenzel, Jörg Bohlender, Katrin Pinsker, Bärbel Wohlleben, Jens Tank, Stefan G Lechner, Daniela Schiska, Teresa Jaijo, Franz Rüschendorf, Kathrin Saar, Jens Jordan, José M Millán, Manfred Gross, Gary R Lewin
Published 2012-01-01

Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons

by Rahul Dhandapani, Cynthia Mary Arokiaraj, Francisco J. Taberner, Paola Pacifico, Sruthi Raja, Linda Nocchi, Carla Portulano, Federica Franciosa, Mariano Maffei, Ahmad Fawzi Hussain, Fernanda de Castro Reis, Luc Reymond, Emerald Perlas, Simone Garcovich, Stefan Barth, Kai Johnsson, Stefan G. Lechner, Paul A. Heppenstall
Published 2018-04-01

Role of TMEM100 in mechanically insensitive nociceptor un-silencing

by Timo A. Nees, Na Wang, Pavel Adamek, Nadja Zeitzschel, Clement Verkest, Carmen La Porta, Irina Schaefer, Julie Virnich, Selin Balkaya, Vincenzo Prato, Chiara Morelli, Valerie Begay, Young Jae Lee, Anke Tappe-Theodor, Gary R. Lewin, Paul A. Heppenstall, Francisco J. Taberner, Stefan G. Lechner
Published 2023-04-01