The candidate genes <it>TAF5L, TCF7, PDCD1</it>, <it>IL6 </it>and <it>ICAM1 </it>cannot be excluded from having effects in type 1 diabetes

by Vella Adrian, Zeitels Lauren R, Masters Jennifer, Godfrey Lisa M, Downes Kate, Payne Felicity, Bailey Rebecca, Smyth Deborah J, Cooper Jason D, Walker Neil M, Todd John A
Published 2007-11-01

Investigating the utility of combining Φ29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray™ genotyping

by Smink Luc J, Lam Alex C, Smith Anne, Twells Rebecca CJ, Sebastian Meera, Smyth Deborah J, Nutland Sarah, Barratt Bryan J, Rance Helen E, Pask Rebecca, Walker Neil M, Todd John A
Published 2004-07-01

Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes

by Smink Luc J, Walker Neil M, Burren Oliver, Lam Alex C, Healy Barry C, Nutland Sarah, Bailey Rebecca, Smyth Deborah J, Cooper Jason D, Lowe Christopher E, Taniguchi Hidenori, Wicker Linda S, Todd John A
Published 2006-04-01

Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases

by Walker Neil M, Nutland Sarah, Lam Alex C, Dahlman Ingrid, Vella Adrian, Hulme John S, Cooper Jason D, Lowe Christopher E, Holland Kieran, Bailey Rebecca, Maier Lisa M, Payne Felicity, Howson Joanna MM, Smyth Deborah J, Twells Rebecca CJ, Todd John A
Published 2006-03-01

Development of an integrated genome informatics, data management and workflow infrastructure: A toolbox for the study of complex disease genetics

by Burren Oliver S, Healy Barry C, Lam Alex C, Schuilenburg Helen, Dolman Geoffrey E, Everett Vincent H, Laneri Davide, Nutland Sarah, Rance Helen E, Payne Felicity, Smyth Deborah, Lowe Chris, Barratt Bryan J, Twells Rebecca CJ, Rainbow Daniel B, Wicker Linda S, Todd John A, Walker Neil M, Smink Luc J
Published 2004-01-01

Sequencing and association analysis of the type 1 diabetes – linked region on chromosome 10p12-q11

by Barratt Bryan J, Twells Rebecca, Smith Anne, Walker Neil M, Nutland Sarah, Stevens Helen, Burren Oliver, Lam Alex, Godfrey Lisa, Masters Jennifer, Payne Felicity, Lowe Christopher E, Bailey Rebecca, Smyth Deborah, Smink Luc J, Nejentsev Sergey, Wright Charmain, French Lisa, Chen Yuan, Deloukas Panagiotis, Rogers Jane, Dunham Ian, Todd John A
Published 2007-05-01

Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes

by Savage David A, Ionescu-Tîrgovişte Constantin, Guja Cristian, Rønningen Kjersti S, Undlien Dag E, Nutland Sarah, Walker Neil, Chamberlain Giselle, Hunter Kara M, Moule Carolyn, Fraser Heather, Smink Luc J, Hulme John, Lowe Christopher, Pask Rebecca, Cooper Jason D, Payne Felicity, Vella Adrian, Smyth Deborah J, Maier Lisa M, Strachan David P, Peterson Laurence B, Todd John A, Wicker Linda S, Twells Rebecca C
Published 2005-02-01

How are companies and workers preparing for the workforce of the future? /

by Smyth, Deborah W., Richter, Ralph A. (Ralph Arthur), 1963-, National Institute of Standards and Technology (U.S.)
Published 2000

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

by Rainbow, Daniel B, Yang, Xin, Burren, Oliver, Pekalski, Marcin L, Smyth, Deborah J, Klarqvist, Marcus DR, Penkett, Christopher J, Brugger, Kim, Martin, Howard, Todd, John A, Wallace, Chris, Wicker, Linda S
Published 2015

Development of an integrated genome informatics, data management and workflow infrastructure: a toolbox for the study of complex disease genetics.

by Burren, Oliver S, Healy, Barry C, Lam, Alex C, Schuilenburg, Helen, Dolman, Geoffrey E, Everett, Vincent H, Laneri, Davide, Nutland, Sarah, Rance, Helen E, Payne, Felicity, Smyth, Deborah, Lowe, Chris, Barratt, Bryan J, Twells, Rebecca CJ, Rainbow, Daniel B, Wicker, Linda S, Todd, John A, Walker, Neil M, Smink, Luc J
Published 2012

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

by Yang, Jennie HM, Cutler, Antony J, Ferreira, Ricardo C, Reading, James L, Cooper, Nicholas J, Wallace, Chris, Clarke, Pamela, Smyth, Deborah J, Boyce, Christopher S, Gao, Guo-Jian, Todd, John A, Wicker, Linda S, Tree, Timothy IM
Published 2015

Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes.

by Taniguchi, Hidenori, Lowe, Christopher E, Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Nutland, Sarah, Healy, Barry C, Lam, Alex C, Burren, Oliver, Walker, Neil M, Smink, Luc J, Wicker, Linda S, Todd, John A
Published 2011

An allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetes.

by Swafford, Austin D-E, Howson, Joanna MM, Davison, Lucy J, Wallace, Chris, Smyth, Deborah J, Schuilenburg, Helen, Maisuria-Armer, Meeta, Mistry, Trupti, Lenardo, Michael J, Todd, John A
Published 2021

A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.

by Evangelou, Marina, Smyth, Deborah J, Fortune, Mary D, Burren, Oliver S, Walker, Neil M, Guo, Hui, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick, Rich, Stephen S, Todd, John A, Wallace, Chris
Published 2014

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

by Cutler, Antony J, Oliveira, Joao, Ferreira, Ricardo C, Challis, Ben, Walker, Neil M, Caddy, Sarah, Lu, Jia, Stevens, Helen E, Smyth, Deborah J, Pekalski, Marcin L, Kennet, Jane, Hunter, Kara MD, Goodfellow, Ian, Wicker, Linda S, Todd, John A, Waldron-Lynch, Frank
Published 2018

The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes.

by Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Payne, Felicity, Downes, Kate, Godfrey, Lisa M, Masters, Jennifer, Zeitels, Lauren R, Vella, Adrian, Walker, Neil M, Todd, John A
Published 2011

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

by Smyth, Deborah J., Walker, Neil M., Stevens, Helen, Burren, Oliver S., Wallace, Chris, Greissl, Christopher, Ramos-Lopez, Elizabeth, Hyppönen, Elina, Dunger, David B., Spector, Timothy D., Ouwehand, Willem H., Badenhoop, Klaus, Cooper, Jason D., Wang, Thomas Jue-Fuu, Todd, John A.
Published 2013

Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes.

by Maier, Lisa M, Smyth, Deborah J, Vella, Adrian, Payne, Felicity, Cooper, Jason D, Pask, Rebecca, Lowe, Christopher, Hulme, John, Smink, Luc J, Fraser, Heather, Moule, Carolyn, Hunter, Kara M, Chamberlain, Giselle, Walker, Neil, Nutland, Sarah, Undlien, Dag E, Rønningen, Kjersti S, Guja, Cristian, Ionescu-Tîrgoviste, Constantin, Savage, David A, Strachan, David P, Peterson, Laurence B, Todd, John A, Wicker, Linda S, Twells, Rebecca C
Published 2011

IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

by Ferreira, Ricardo C, Simons, Henry Z, Thompson, Whitney S, Cutler, Antony J, Dopico, Xaquin Castro, Smyth, Deborah J, Mashar, Meghavi, Schuilenburg, Helen, Walker, Neil M, Dunger, David B, Wallace, Chris, Todd, John A, Wicker, Linda S, Pekalski, Marcin L
Published 2015

Widespread seasonal gene expression reveals annual differences in human immunity and physiology.

by Dopico, Xaquin Castro, Evangelou, Marina, Ferreira, Ricardo C, Guo, Hui, Pekalski, Marcin L, Smyth, Deborah J, Cooper, Nicholas, Burren, Oliver S, Fulford, Anthony J, Hennig, Branwen J, Prentice, Andrew M, Ziegler, Anette-G, Bonifacio, Ezio, Wallace, Chris, Todd, John A
Published 2015