A Dual-Plasmid-Based CRISPR/Cas9-Mediated Strategy Enables Targeted Editing of pH Regulatory Gene <i>pacC</i> in a Clinical Isolate of <i>Trichophyton rubrum</i>

by Sanchita Sanchaya Dey, Sivaprakash Ramalingam, Bhupesh Taneja
Published 2022-11-01

The CRISPR/Cas9 System for Targeted Genome Engineering in Free-Living Fungi: Advances and Opportunities for Lichenized Fungi

by Karthik Shanmugam, Karthik Shanmugam, Sivaprakash Ramalingam, Gayathri Venkataraman, G. N. Hariharan
Published 2019-02-01

Generation and characterization of induced pluripotent stem cell line (IGIBi001-A) from a sickle cell anemia patient with homozygous β-globin mutation

by Nupur Bhargava, Shashank Jaitly, Sangam Giri Goswami, Suman Jain, Debojyoti Chakraborty, Sivaprakash Ramalingam
Published 2019-08-01

The mitochondrial gene-CMPK2 functions as a rheostat for macrophage homeostasis

by Prabhakar Arumugam, Prabhakar Arumugam, Meghna Chauhan, Meghna Chauhan, Thejaswitha Rajeev, Rahul Chakraborty, Rahul Chakraborty, Kanika Bisht, Kanika Bisht, Mahima Madan, Mahima Madan, Deepthi Shankaran, Deepthi Shankaran, Sivaprakash Ramalingam, Sivaprakash Ramalingam, Sheetal Gandotra, Sheetal Gandotra, Vivek Rao, Vivek Rao
Published 2022-11-01

Generation of an induced pluripotent stem cell line IGIBi18-A from an Indian patient with Rubinstein Taybi Syndrome

by Shweta Verma, Sujit Dalabehera, Ranjeet Maurya, Dayanidhi Singh, Bhavana Prasher, Rajesh Pandey, Sharmila Bapat, Sivaprakash Ramalingam, Chetana Sachidanandan
Published 2024-08-01

Establishment and characterization of induced pluripotent stem cell line (IGIBi002-A) from a β-thalassemia patient with IVS1-5 mutation by non-integrating reprogramming approach

by Priya Thakur, Nupur Bhargava, Shashank Jaitly, Pragya Gupta, Saurabh Kumar Bhattacharya, G. Padma, Saroja Kondaveeti, Suman Jain, Sivaprakash Ramalingam
Published 2021-01-01

A Simple, Cost-Effective, and Extraction-Free Molecular Diagnostic Test for Sickle Cell Disease Using a Noninvasive Buccal Swab Specimen for a Limited-Resource Setting

by Priya Thakur, Pragya Gupta, Nupur Bhargava, Rajat Soni, Narendra Varma Gottumukkala, Sangam Giri Goswami, Gaurav Kharya, Vinodh Saravanakumar, Padma Gunda, Suman Jain, Jasmita Dass, Mukul Aggarwal, Sivaprakash Ramalingam
Published 2022-07-01

Scalable noninvasive amplicon-based precision sequencing (SNAPseq) for genetic diagnosis and screening of β-thalassemia and sickle cell disease using a next-generation sequencing p...

by Pragya Gupta, Pragya Gupta, V. R. Arvinden, V. R. Arvinden, Priya Thakur, Priya Thakur, Rahul C. Bhoyar, Vinodh Saravanakumar, Narendra Varma Gottumukkala, Sangam Giri Goswami, Sangam Giri Goswami, Mehwish Nafiz, Mehwish Nafiz, Aditya Ramdas Iyer, Aditya Ramdas Iyer, Harie Vignesh, Rajat Soni, Nupur Bhargava, Padma Gunda, Suman Jain, Vivek Gupta, Sridhar Sivasubbu, Sridhar Sivasubbu, Vinod Scaria, Vinod Scaria, Sivaprakash Ramalingam, Sivaprakash Ramalingam
Published 2023-12-01

A conserved SNP variation in the pre-miR396c flanking region in Oryza sativa indica landraces correlates with mature miRNA abundance

by Deepa Jaganathan, Raja Rajakani, Dadakhalandar Doddamani, Divya Saravanan, Shalini Pulipati, Vivek Hari Sundar G, Gothandapani Sellamuthu, Shilpha Jayabalan, Kumkum Kumari, Pavithra Parthasarathy, Punitha S., Sivaprakash Ramalingam, Padubidri V. Shivaprasad, Gayatri Venkataraman
Published 2023-02-01

Development of pathophysiologically relevant models of sickle cell disease and β-thalassemia for therapeutic studies

by Pragya Gupta, Sangam Giri Goswami, Geeta Kumari, Vinodh Saravanakumar, Nupur Bhargava, Akhila Balakrishna Rai, Praveen Singh, Rahul C. Bhoyar, V. R. Arvinden, Padma Gunda, Suman Jain, Vanya Kadla Narayana, Sayali C. Deolankar, T. S. Keshava Prasad, Vivek T. Natarajan, Vinod Scaria, Shailja Singh, Sivaprakash Ramalingam
Published 2024-02-01

Targeting PfProhibitin 2-Hu-Hsp70A1A complex as a unique approach towards malaria vaccine development

by Manisha Marothia, Ankita Behl, Preeti Maurya, Monika Saini, Rumaisha Shoaib, Swati Garg, Geeta Kumari, Shreeja Biswas, Akshay Munjal, Sakshi Anand, Amandeep Kaur Kahlon, Pragya Gupta, Saurav Biswas, Bidhan Goswami, Haider Thaer Abdulhameed Almuqdadi, Ipsita Pal Bhowmick, Maxim Shevtsov, Sivaprakash Ramalingam, Anand Ranganathan, Shailja Singh
Published 2024-06-01

Genetic epidemiology of autoinflammatory disease variants in Indian population from 1029 whole genomes

by Abhinav Jain, Rahul C. Bhoyar, Kavita Pandhare, Anushree Mishra, Disha Sharma, Mohamed Imran, Vigneshwar Senthivel, Mohit Kumar Divakar, Mercy Rophina, Bani Jolly, Arushi Batra, Sumit Sharma, Sanjay Siwach, Arun G. Jadhao, Nikhil V. Palande, Ganga Nath Jha, Nishat Ashrafi, Prashant Kumar Mishra, Vidhya A.K., Suman Jain, Debasis Dash, Nachimuthu Senthil Kumar, Andrew Vanlallawma, Ranjan Jyoti Sarma, Lalchhandama Chhakchhuak, Shantaraman Kalyanaraman, Radha Mahadevan, Sunitha Kandasamy, Pabitha B. M, Raskin Erusan Rajagopal, Ezhil Ramya J., Nirmala Devi P., Anjali Bajaj, Vishu Gupta, Samatha Mathew, Sangam Goswami, Mohit Mangla, Savinitha Prakash, Kandarp Joshi, Meyakumla, Sreedevi S., Devarshi Gajjar, Ronibala Soraisham, Rohit Yadav, Yumnam Silla Devi, Aayush Gupta, Mitali Mukerji, Sivaprakash Ramalingam, Binukumar B. K., Vinod Scaria, Sridhar Sivasubbu
Published 2021-12-01