Systematic analysis of disease‐specific immunological signatures in patients with febrile illness from Saudi Arabia

by Yiu‐Wing Kam, Mohamed Yousif Ahmed, Siti Naqiah Amrun, Bernett Lee, Tarik Refaie, Kamla Elgizouli, Siew‐Wai Fong, Laurent Renia, Lisa FP Ng
Published 2020-01-01

Safety and potential efficacy of cyclooxygenase‐2 inhibitors in coronavirus disease 2019

by Sean Wei Xiang Ong, Wilnard Yeong Tze Tan, Yi‐Hao Chan, Siew‐Wai Fong, Laurent Renia, Lisa FP Ng, Yee‐Sin Leo, David Chien Lye, Barnaby Edward Young
Published 2020-01-01

Myeloperoxidase inhibition may protect against endothelial glycocalyx shedding induced by COVID-19 plasma

by Andrew Teo, Louisa L. Y. Chan, Christine Cheung, Po Ying Chia, Sean Wei Xiang Ong, Siew Wai Fong, Lisa F. P. Ng, Laurent Renia, David Chien Lye, Barnaby Edward Young, Tsin Wen Yeo
Published 2023-05-01

Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir

by Yi-Hao Chan, Yi-Hao Chan, Barnaby E. Young, Barnaby E. Young, Barnaby E. Young, Siew-Wai Fong, Siew-Wai Fong, Ying Ding, Yun Shan Goh, Yun Shan Goh, Rhonda Sin-Ling Chee, Rhonda Sin-Ling Chee, Seow-Yen Tan, Shirin Kalimuddin, Shirin Kalimuddin, Paul A. Tambyah, Yee-Sin Leo, Yee-Sin Leo, Yee-Sin Leo, Yee-Sin Leo, Yee-Sin Leo, Lisa F. P. Ng, Lisa F. P. Ng, Lisa F. P. Ng, Lisa F. P. Ng, David Chien Lye, David Chien Lye, David Chien Lye, David Chien Lye, Laurent Renia, Laurent Renia
Published 2021-06-01

Associations of viral ribonucleic acid (RNA) shedding patterns with clinical illness and immune responses in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) infection...

by Pei Hua Lee, Woo Chiao Tay, Stephanie Sutjipto, Siew‐Wai Fong, Sean Wei Xiang Ong, Wycliff Enli Wei, Yi‐Hao Chan, Li Min Ling, Barnaby E Young, Matthias Paul HS Toh, Laurent Renia, Lisa FP Ng, Yee‐Sin Leo, David C Lye, Tau Hong Lee
Published 2020-01-01

Crosstalk between CD64+MHCII+ macrophages and CD4+ T cells drives joint pathology during chikungunya

by Fok-Moon Lum, Yi-Hao Chan, Teck-Hui Teo, Etienne Becht, Siti Naqiah Amrun, Karen WW Teng, Siddesh V Hartimath, Nicholas KW Yeo, Wearn-Xin Yee, Nicholas Ang, Anthony M Torres-Ruesta, Siew-Wai Fong, Julian L Goggi, Evan W Newell, Laurent Renia, Guillaume Carissimo, Lisa FP Ng
Published 2024-02-01

Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation

by Florence WJ Chioh, Siew-Wai Fong, Barnaby E Young, Kan-Xing Wu, Anthony Siau, Shuba Krishnan, Yi-Hao Chan, Guillaume Carissimo, Louis LY Teo, Fei Gao, Ru San Tan, Liang Zhong, Angela S Koh, Seow-Yen Tan, Paul A Tambyah, Laurent Renia, Lisa FP Ng, David C Lye, Christine Cheung
Published 2021-03-01

Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore

by Bei Wang, Yun Shan Goh, Tessa Prince, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Pei Xiang Hor, Chiew Yee Loh, Siew Wai Fong, Catherine Hartley, Seow-Yen Tan, Barnaby Edward Young, Yee-Sin Leo, David C. Lye, Sebastian Maurer-Stroh, Lisa F. P. Ng, Julian A. Hiscox, Laurent Renia, Cheng-I Wang
Published 2021-10-01

Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals

by Jackwee Lim, Kia Joo Puan, Liang Wei Wang, Karen Wei Weng Teng, Chiew Yee Loh, Kim Peng Tan, Guillaume Carissimo, Guillaume Carissimo, Yi-Hao Chan, Yi-Hao Chan, Chek Meng Poh, Chek Meng Poh, Cheryl Yi-Pin Lee, Cheryl Yi-Pin Lee, Siew-Wai Fong, Siew-Wai Fong, Siew-Wai Fong, Nicholas Kim-Wah Yeo, Nicholas Kim-Wah Yeo, Rhonda Sin-Ling Chee, Rhonda Sin-Ling Chee, Siti Naqiah Amrun, Siti Naqiah Amrun, Zi Wei Chang, Zi Wei Chang, Matthew Zirui Tay, Matthew Zirui Tay, Anthony Torres-Ruesta, Anthony Torres-Ruesta, Anthony Torres-Ruesta, Norman Leo Fernandez, Wilson How, Anand Kumar Andiappan, Wendy Lee, Kaibo Duan, Seow-Yen Tan, Gabriel Yan, Shirin Kalimuddin, Shirin Kalimuddin, David Chien Lye, David Chien Lye, David Chien Lye, David Chien Lye, Yee-Sin Leo, Yee-Sin Leo, Yee-Sin Leo, Yee-Sin Leo, Yee-Sin Leo, Sean W. X. Ong, Sean W. X. Ong, Barnaby E. Young, Barnaby E. Young, Barnaby E. Young, Laurent Renia, Laurent Renia, Lisa F. P. Ng, Lisa F. P. Ng, Lisa F. P. Ng, Lisa F. P. Ng, Bernett Lee, Olaf Rötzschke
Published 2021-11-01

Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity

by Quy Xiao Xuan Lin, Deepa Rajagopalan, Akshamal M. Gamage, Le Min Tan, Prasanna Nori Venkatesh, Wharton O. Y. Chan, Dilip Kumar, Ragini Agrawal, Yao Chen, Siew-Wai Fong, Amit Singh, Louisa J. Sun, Seow-Yen Tan, Louis Yi Ann Chai, Jyoti Somani, Bernett Lee, Laurent Renia, Lisa F P Ng, Kollengode Ramanathan, Lin-Fa Wang, Barnaby Young, David Lye, Amit Singhal, Shyam Prabhakar
Published 2024-01-01

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

by Guillaume Carissimo, Weili Xu, Immanuel Kwok, Mohammad Yazid Abdad, Yi-Hao Chan, Siew-Wai Fong, Kia Joo Puan, Cheryl Yi-Pin Lee, Nicholas Kim-Wah Yeo, Siti Naqiah Amrun, Rhonda Sin-Ling Chee, Wilson How, Stephrene Chan, Bingwen Eugene Fan, Anand Kumar Andiappan, Bernett Lee, Olaf Rötzschke, Barnaby Edward Young, Yee-Sin Leo, David Chien Lye, Laurent Renia, Lai Guan Ng, Anis Larbi, Lisa FP Ng
Published 2020-10-01

Human neutralising antibodies elicited by SARS‐CoV‐2 non‐D614G variants offer cross‐protection against the SARS‐CoV‐2 D614G variant

by Cheryl Yi‐Pin Lee, Siti Naqiah Amrun, Rhonda Sin‐Ling Chee, Yun Shan Goh, Tze‐Minn Mak, Sophie Octavia, Nicholas Kim‐Wah Yeo, Zi Wei Chang, Matthew Zirui Tay, Anthony Torres‐Ruesta, Guillaume Carissimo, Chek Meng Poh, Siew‐Wai Fong, Wang Bei, Sandy Lee, Barnaby Edward Young, Seow‐Yen Tan, Yee‐Sin Leo, David C Lye, Raymond TP Lin, Sebastien Maurer‐Stroh, Bernett Lee, Cheng‐I Wang, Laurent Renia, Lisa FP Ng
Published 2021-01-01

Asymptomatic COVID‐19: disease tolerance with efficient anti‐viral immunity against SARS‐CoV‐2

by Yi‐Hao Chan, Siew‐Wai Fong, Chek‐Meng Poh, Guillaume Carissimo, Nicholas Kim‐Wah Yeo, Siti Naqiah Amrun, Yun Shan Goh, Jackwee Lim, Weili Xu, Rhonda Sin‐Ling Chee, Anthony Torres‐Ruesta, Cheryl Yi‐Pin Lee, Matthew Zirui Tay, Zi Wei Chang, Wen‐Hsin Lee, Bei Wang, Seow‐Yen Tan, Shirin Kalimuddin, Barnaby Edward Young, Yee‐Sin Leo, Cheng‐I Wang, Bernett Lee, Olaf Rötzschke, David Chien Lye, Laurent Renia, Lisa F P Ng
Published 2021-06-01

Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

by Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Bernett Lee, Siew-Wai Fong, Barnaby Edward Young, Rhonda Sin-Ling Chee, Nicholas Kim-Wah Yeo, Anthony Torres-Ruesta, Guillaume Carissimo, Chek Meng Poh, Zi Wei Chang, Matthew Zirui Tay, Yi-Hao Chan, Mark I-Cheng Chen, Jenny Guek-Hong Low, Paul A. Tambyah, Shirin Kalimuddin, Surinder Pada, Seow-Yen Tan, Louisa Jin Sun, Yee-Sin Leo, David C. Lye, Laurent Renia, Lisa F.P. Ng
Published 2020-08-01

Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study

by Barnaby E Young, Wycliffe E Wei, Siew-Wai Fong, Tze-Minn Mak, Danielle E Anderson, Yi-Hao Chan, Rachael Pung, Cheryl SY Heng, Li Wei Ang, Adrian Kang Eng Zheng, Bernett Lee, Shirin Kalimuddin, Surinder Pada, Paul A Tambyah, Purnima Parthasarathy, Seow Yen Tan, Louisa Sun, Gavin JD Smith, Raymond Tzer Pin Lin, Yee-Sin Leo, Laurent Renia, Lin-Fa Wang, Lisa FP Ng, Sebastian Maurer-Stroh, David Chien Lye, Vernon J Lee
Published 2021-04-01

Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients

by Chek Meng Poh, Guillaume Carissimo, Bei Wang, Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Rhonda Sin-Ling Chee, Siew-Wai Fong, Nicholas Kim-Wah Yeo, Wen-Hsin Lee, Anthony Torres-Ruesta, Yee-Sin Leo, Mark I-Cheng Chen, Seow-Yen Tan, Louis Yi Ann Chai, Shirin Kalimuddin, Shirley Seah Gek Kheng, Siew-Yee Thien, Barnaby Edward Young, David C. Lye, Brendon John Hanson, Cheng-I Wang, Laurent Renia, Lisa F. P. Ng
Published 2020-06-01

Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

by Yun Shan Goh, Siew-Wai Fong, Matthew Zirui Tay, Angeline Rouers, Zi Wei Chang, Jean-Marc Chavatte, Pei Xiang Hor, Chiew Yee Loh, Yuling Huang, Yong Jie Tan, Bei Wang, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Raphael Tze Chuen Lee, Georgina Lim, NCID Study Group, COVID-Study Group, Sebastian Maurer-Stroh, Cheng-I Wang, Yee‐Sin Leo, Raymond T. P. Lin, Meng Chon Lam, David C. Lye, Barnaby Edward Young, Lisa F. P. Ng, Laurent Renia
Published 2023-11-01

Author Correction: Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta w...

by Yun Shan Goh, Siew-Wai Fong, Matthew Zirui Tay, Angeline Rouers, Zi Wei Chang, Jean-Marc Chavatte, Pei Xiang Hor, Chiew Yee Loh, Yuling Huang, Yong Jie Tan, Bei Wang, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Raphael Tze Chuen Lee, Georgina Lim, NCID Study Group, COVID-Study Group, Sebastian Maurer-Stroh, Cheng-I Wang, Yee‐Sin Leo, Raymond T. P. Lin, Meng Chon Lam, David C. Lye, Barnaby Edward Young, Lisa F. P. Ng, Laurent Renia
Published 2024-01-01

Resistance of SARS-CoV-2 Delta variant to neutralization by BNT162b2-elicited antibodies in Asians

by Bei Wang, Yun Shan Goh, Siew-Wai Fong, Barnaby Edward Young, Eve Zi Xian Ngoh, Jean-Marc Chavatte, Siti Nazihah Mohd Salleh, Nicholas Kim-Wah Yeo, Siti Naqiah Amrun, Pei Xiang Hor, Chiew Yee Loh, Chia Yin Lee, Yi-Hao Chan, Zi Wei Chang, Matthew Zirui Tay, Angeline Rouers, Anthony Torres-Ruesta, Guillaume Carissimo, Mun Kuen Soh, Raphael Tze Chuen Lee, Yani Xu, Surinder Pada, Raymond Tzer Pin Lin, Yee-Sin Leo, David C. Lye, Sebastian Maurer-Stroh, Lisa F.P. Ng, Laurent Renia, Cheng-I Wang
Published 2021-10-01

Decreased memory B cell frequencies in COVID‐19 delta variant vaccine breakthrough infection

by Matthew Zirui Tay, Angeline Rouers, Siew‐Wai Fong, Yun Shan Goh, Yi‐Hao Chan, Zi Wei Chang, Weili Xu, Chee Wah Tan, Wan Ni Chia, Anthony Torres‐Ruesta, Siti Naqiah Amrun, Yuling Huang, Pei Xiang Hor, Chiew Yee Loh, Nicholas Kim‐Wah Yeo, Bei Wang, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Jean‐Marc Chavatte, Alicia Jieling Lim, Sebastian Maurer‐Stroh, Lin‐Fa Wang, Raymond Valentine Tzer Pin Lin, Cheng‐I Wang, Seow‐Yen Tan, Barnaby Edward Young, Yee‐Sin Leo, David C Lye, Laurent Renia, Lisa FP Ng
Published 2022-03-01